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The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region.
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1 reference
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Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
title
The single-stranded DNA end binding site of p53 coincides with the C-terminal regulatory region
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
author
Galina Selivanova
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Georgy Bakalkin
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
Klas Wiman
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
author name string
V Iotsova
series ordinal
2
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Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
E Kiseleva
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
M Ström
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
R C Grafström
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
language of work or name
English
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publication date
1 September 1996
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
number of pages
8
1 reference
based on heuristic
inferred from page(s)
published in
Nucleic Acids Research
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
volume
24
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
issue
18
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
page(s)
3560-3567
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
cites work
Regulation of specific DNA binding by p53: evidence for a role for O-glycosylation and charged residues at the carboxy-terminus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
mdm2 expression is induced by wild type p53 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
The p53-mdm-2 autoregulatory feedback loop
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
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6 September 2017
WAF1, a potential mediator of p53 tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Human p53 directs DNA strand reassociation and is photolabelled by 8-azido ATP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Cyclin G is a transcriptional target of the p53 tumor suppressor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Allosteric activation of latent p53 tetramers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
p53 oligomerization and DNA looping are linked with transcriptional activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
The C-terminal domain of p53 recognizes DNA damaged by ionizing radiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
[Leu5]enkephalin-encoding sequences are targets for a specific DNA-binding factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Mutations in p53 as potential molecular markers for human breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Participation of p53 protein in the cellular response to DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
A DNA binding domain is contained in the C-terminus of wild type p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Oncogenic forms of p53 inhibit p53-regulated gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
p53 function and dysfunction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Regulation of the specific DNA binding function of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
Definition of a consensus binding site for p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
6 September 2017
p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
14 September 2017
p53: a cell cycle regulator activated by DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
14 September 2017
Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
27 September 2017
p53: at the crossroads of molecular carcinogenesis and risk assessment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
27 September 2017
Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
23 June 2018
Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
23 June 2018
Presence of a potent transcription activating sequence in the p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
23 June 2018
A C-terminal alpha-helix plus basic region motif is the major structural determinant of p53 tetramerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
23 June 2018
Thymocyte apoptosis induced by p53-dependent and independent pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
31 August 2018
p53 domains: identification and characterization of two autonomous DNA-binding regions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
31 August 2018
Small peptides activate the latent sequence-specific DNA binding function of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
31 August 2018
Different forms of p53 detected by monoclonal antibodies in non-dividing and dividing lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146129
retrieved
31 August 2018
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8836183
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High levels of p53 protein in UV-irradiated normal human skin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8836183
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1093/NAR/24.18.3560
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
PMC publication ID
146129
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
PubMed publication ID
8836183
1 reference
stated in
Europe PubMed Central
PMC publication ID
146129
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8836183%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
ResearchGate publication ID
277524962
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