(Q38357883)

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Versatile method employing basic techniques of genetic engineering to study the ability of low-molecular-weight compounds to bind covalently with DNA in cell-free systems.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

Versatile method employing basic techniques of genetic engineering to study the ability of low-molecular-weight compounds to bind covalently with DNA in cell-free systems (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

Agnieszka Bartoszek-Pączkowska

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

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Anna Sielenko

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

Magdalena Wesiora

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

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1 February 2003

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18 December 2019

Analytical Biochemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

313

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18 December 2019

1

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18 December 2019

53-59

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18 December 2019

Mechanisms of chemical carcinogenesis

1 reference

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Relationships between DNA adduct formation and carcinogenesis

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Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites

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A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDS

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Future directions in the use of DNA adducts as internal dosimeters for monitoring human exposure to environmental mutagens and carcinogens

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32P-postlabeling analysis of non-radioactive aromatic carcinogen--DNA adducts.

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Standardization and validation of DNA adduct postlabelling methods: report of interlaboratory trials and production of recommended protocols

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Chemical reactivity of monofunctional platinum-DNA adducts

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7 January 2021

Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity

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In vivo formation and persistence of modified nucleosides resulting from alkylating agents

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Reaction of the antitumor antibiotic CC-1065 with DNA: structure of a DNA adduct with DNA sequence specificity

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7 January 2021

In vitro binding of metabolically activated [14C]-Ledakrin, or 1-nitro-9-14C-(3′-dimethylamino-n-propylamino) acridine, a new antitumor and DNA cross-linking agent, to macromolecules of subcellular fractions isolated from rat liver and HeLa cells

1 reference

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7 January 2021

32P-post-labeling analysis of DNA adduct formation by antitumor drug nitracrine (Ledakrin) and other nitroacridines in different biological systems

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7 January 2021

Determination of covalent binding to intact DNA, RNA, and oligonucleotides by intercalating anticancer drugs using high-performance liquid chromatography. Studies with doxorubicin and NADPH cytochrome P-450 reductase

1 reference

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7 January 2021

32P-postlabelling analysis of adducts formed by mitoxantrone and ametantrone with DNA and homopolydeoxyribonucleotides after enzymatic activation.

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The Mechanism of Action of Antitumor Platinum Compounds

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7 January 2021

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10.1016/S0003-2697(02)00564-X

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12576058%20AND%20SRC:MED&resulttype=core&format=json

18 December 2019

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