(Q38359813)

2 September 2017

title

Bcl-2 controls caspase activation following a p53-dependent cyclin D1-induced death signal (English)

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2 September 2017

M A Christine Pratt

1

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2 September 2017

Min-Ying Niu

series ordinal

2

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2 September 2017

language of work or name

English

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publication date

11 December 2002

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Journal of Biological Chemistry

2 September 2017

published in

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2 September 2017

volume

278

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2 September 2017

issue

16

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2 September 2017

page(s)

14219-14229

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Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

2 September 2017

cites work

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21 January 2018

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Overexpression of cdk4/cyclin D1 induces apoptosis in PC12 cells in the presence of trophic support.

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M209650200

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M209650200

21 January 2018

Bcl-2 family proteins

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https://api.crossref.org/works/10.1074%2FJBC.M209650200

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

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Conformation of the Bax C-terminus regulates subcellular location and cell death

21 January 2018

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Movement of Bax from the cytosol to mitochondria during apoptosis

21 January 2018

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Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

1 reference

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

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IAP family proteins--suppressors of apoptosis

21 January 2018

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An exegesis of IAPs: salvation and surprises from BIR motifs

21 January 2018

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

21 January 2018

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Apoptosis without caspases: an inefficient molecular guillotine?

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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Ectopic expression of cyclin D1 amplifies a retinoic acid-induced mitochondrial death pathway in breast cancer cells

21 January 2018

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Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

21 January 2018

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Mitochondria as the central control point of apoptosis

21 January 2018

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The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

21 January 2018

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Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.

21 January 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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PBP74, a new member of the mammalian 70-kDa heat shock protein family, is a mitochondrial protein

21 January 2018

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Regulation of the G2/M transition by p53.

21 January 2018

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Activation and activities of the p53 tumour suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

Bcl-2 inhibits a Fas-induced conformational change in the Bax N terminus and Bax mitochondrial translocation.

21 January 2018

1 reference

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Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

21 January 2018

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

21 January 2018

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Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

21 January 2018

1 reference

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Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

21 January 2018

1 reference

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Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

21 January 2018

1 reference

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Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release

21 January 2018

1 reference

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Proapoptotic BH3-only Bcl-2 family members induce cytochrome c release, but not mitochondrial membrane potential loss, and do not directly modulate voltage-dependent anion channel activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

21 January 2018

1 reference

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Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

Inhibition of Bak-induced apoptosis by HPV-18 E6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M209650200

21 January 2018

Identifiers

DOI

10.1074/JBC.M209650200

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2 September 2017

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