(Q38363610)

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Down-regulation of human type II collagen gene expression by transforming growth factor-beta 1 (TGF-beta 1) in articular chondrocytes involves SP3/SP1 ratio

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 September 2017

Down-regulation of human type II collagen gene expression by transforming growth factor-beta 1 (TGF-beta 1) in articular chondrocytes involves SP3/SP1 ratio (English)

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Europe PubMed Central

PubMed publication ID

2 September 2017

author name string

Christos Chadjichristos

1

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Europe PubMed Central

PubMed publication ID

2 September 2017

Chafik Ghayor

2

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Europe PubMed Central

PubMed publication ID

2 September 2017

Jean-Francois Herrouin

3

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Europe PubMed Central

PubMed publication ID

2 September 2017

Leena Ala-Kokko

4

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

Gunthram Suske

5

1 reference

Europe PubMed Central

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2 September 2017

Jean-Pierre Pujol

6

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Europe PubMed Central

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2 September 2017

Philippe Galéra

7

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Europe PubMed Central

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2 September 2017

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publication date

16 August 2002

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Europe PubMed Central

PubMed publication ID

2 September 2017

number of pages

15

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

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2 September 2017

277

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Europe PubMed Central

PubMed publication ID

2 September 2017

46

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Europe PubMed Central

PubMed publication ID

2 September 2017

43903-43917

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Europe PubMed Central

PubMed publication ID

2 September 2017

Some recent advances in the chemistry and biology of transforming growth factor-beta

1 reference

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21 January 2018

Differential effects of IGF-1 and TGF beta-2 on the assembly of proteoglycans in pericellular and territorial matrix by cultured bovine articular chondrocytes

1 reference

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21 January 2018

Expression of decorin and biglycan by rabbit articular chondrocytes. Effects of cytokines and phenotypic modulation

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21 January 2018

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin

1 reference

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21 January 2018

Smads: transcriptional activators of TGF-beta responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

1 reference

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21 January 2018

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

1 reference

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21 January 2018

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

1 reference

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21 January 2018

Divergence and convergence of TGF-beta/BMP signaling

1 reference

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21 January 2018

Smad4 and FAST-1 in the assembly of activin-responsive factor

1 reference

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21 January 2018

Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-beta -induced physical and functional interactions between smads and Sp1.

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21 January 2018

Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

1 reference

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21 January 2018

Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells

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21 January 2018

Transforming growth factor-beta up-regulates the beta 5 integrin subunit expression via Sp1 and Smad signaling.

1 reference

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21 January 2018

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Smads bind directly to the Jun family of AP-1 transcription factors

1 reference

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21 January 2018

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Smads as transcriptional co-modulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Transcriptional control by the TGF-beta/Smad signaling system

1 reference

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21 January 2018

p38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells

1 reference

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21 January 2018

Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Interleukin-1 and osteoarthritis

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21 January 2018

Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

The control of expression of type II collagen: relevance to cartilage disease

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21 January 2018

Differences in Collagen Metabolism between Normal and Osteoarthritic Human Articular Cartilage

1 reference

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21 January 2018

Regulation of human COL2A1 gene expression in chondrocytes. Identification of C-Krox-responsive elements and modulation by phenotype alteration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

The Sp-family of transcription factors

1 reference

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21 January 2018

Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury

1 reference

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21 January 2018

Synergistic action of transforming growth factor-beta and insulin-like growth factor-I induces expression of type II collagen and aggrecan genes in adult human articular chondrocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Effect of type II collagen in chondrocyte response to TGF-beta 1 regulation

1 reference

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21 January 2018

Dexamethasone inhibition of TGF beta-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Signaling activity of homologous and heterologous transforming growth factor-beta receptor kinase complexes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

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21 January 2018

A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1 reference

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21 January 2018

Preferential expression of alternatively spliced transcript of type II procollagen in the rabbit notochordal remnant and developing fibrocartilages

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Transforming growth factor-beta modulates the expression of osteoblast and chondroblast phenotypes in vitro

1 reference

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21 January 2018

Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

NF-kappaB inhibits expression of the alpha1(I) collagen gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2(I)-collagen (COL1A2) transcription

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

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Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation

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21 January 2018

TGF beta signals through a heteromeric protein kinase receptor complex

1 reference

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21 January 2018

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Sp3 is a transcriptional repressor of transforming growth factor-beta receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene

1 reference

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Effect of Transforming Growth Factor-β on the Insulin-like Growth Factor-I Autocrine/Paracrine Axis in Cultured Rat Articular Chondrocytes

1 reference

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21 January 2018

Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators

1 reference

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21 January 2018

Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor beta-mediated signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Interleukin-1-induced suppression of type II collagen gene transcription involves DNA regulatory elements

1 reference

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Type X collagen synthesis in human osteoarthritic cartilage. Indication of chondrocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

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Sp3 represses the Sp1-mediated transactivation of the human COL2A1 gene in primary and de-differentiated chondrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Transforming growth factor-β1 (TGF-β1) up-regulation of collagen type II in primary cultures of rabbit articular chondrocytes (RAC) involves increased mRNA levels without affecting mRNA stability and procollagen processing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Effect of transforming growth factor-β1 (TGF-β1) on matrix synthesis by monolayer cultures of rabbit articular chondrocytes during the dedifferentiation process

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Transforming growth factor-beta and fibroblast growth factor act synergistically to inhibit collagen II synthesis through a mechanism involving regulatory DNA sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Transrepression of type II collagen by TGF-beta and FGF is protein kinase C dependent and is mediated through regulatory sequences in the promoter and first intron

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

The progeny of rabbit articular chondrocytes synthesize collagen types I and III and type I trimer, but not type II. Verifications by cyanogen bromide peptide analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Human Sp3 transcriptional regulator gene (SP3) maps to chromosome 2q31

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

The inducible production of nitric oxide by articular cell types

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Rabbit Articular Chondrocytes (RAC) Express Distinct Transforming Growth Factor-β Receptor Phenotypes as a Function of Cell Cycle Phases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Transforming growth factor beta stimulates collagen and glycosaminoglycan biosynthesis in cultured rabbit articular chondrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206111200

21 January 2018

Characterization of proteoglycans synthesized by rabbit articular chondrocytes in response to transforming growth factor-beta (TGF-beta)

1 reference

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Truncation of Sp1 transcription factor by myeloblastin in undifferentiated HL60 cells

1 reference

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Regulation of human monoamine oxidase B gene by Sp1 and Sp3.

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21 January 2018

Identifiers

10.1074/JBC.M206111200

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

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