(Q38363728)

2 September 2017

Specific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain (English)

1 reference

2 September 2017

Thomas Göhler

1

1 reference

2 September 2017

Maurice Reimann

2

1 reference

2 September 2017

Dimitry Cherny

3

1 reference

2 September 2017

Korden Walter

4

1 reference

2 September 2017

Gabriele Warnecke

5

1 reference

2 September 2017

Ella Kim

6

1 reference

2 September 2017

Wolfgang Deppert

7

1 reference

2 September 2017

language of work or name

English

0 references

publication date

8 August 2002

1 reference

Journal of Biological Chemistry

2 September 2017

1 reference

2 September 2017

277

1 reference

2 September 2017

41192-41203

1 reference

2 September 2017

43

1 reference

Definition of a consensus binding site for p53

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Regulation of the specific DNA binding function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Reciprocal interference between the sequence-specific core and nonspecific C-terminal DNA binding domains of p53: implications for regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

A polymorphic microsatellite that mediates induction of PIG3 by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Influence of promoter DNA topology on sequence-specific DNA binding and transactivation by tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Specific mismatch recognition in heteroduplex intermediates by p53 suggests a role in fidelity control of homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Tumor suppressor protein p53 binds preferentially to supercoiled DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Regulation of the specific DNA binding activity of Xenopus laevis p53: evidence for conserved regulation through the carboxy-terminus of the protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Interaction of p53 with its consensus DNA-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Identification and analysis of all components of a gel retardation assay by combination with immunoblotting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

A new preparation method for dark-field electron microscopy of biomacromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Specific recognition of cruciform DNA by nuclear protein HMG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Sequence-specific transcriptional activation is essential for growth suppression by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

High affinity insertion/deletion lesion binding by p53. Evidence for a role of the p53 central domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

The N terminus of p53 regulates its dissociation from DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

How p53 binds DNA as a tetramer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

The dynamic distribution and quantification of DNA cruciforms in eukaryotic nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

DNA cruciforms and the nuclear supporting structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Unusual DNA structures, chromatin and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

In vivo evidence for binding of p53 to consensus binding sites in the p21 and GADD45 genes in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

High mobility group protein-1 (HMG-1) is a unique activator of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Hairpin formation within the human enkephalin enhancer region. 1. Kinetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Secondary structure creates mismatched base pairs required for high-affinity binding of cAMP response element-binding protein to the human enkephalin enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Anti-cruciform DNA affinity purification of active mammalian origins of replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

The human cruciform-binding protein, CBP, is involved in DNA replication and associates in vivo with mammalian replication origins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

p53 accumulates but is functionally impaired when DNA synthesis is blocked

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

The c-fos proto-oncogene is a target for transactivation by the p53 tumor suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

PUMA induces the rapid apoptosis of colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

A model for p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

p53 stimulates transcription from the human transforming growth factor alpha promoter: a potential growth-stimulatory role for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Induction of the growth inhibitor IGF-binding protein 3 by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

The gene encoding p202, an interferon-inducible negative regulator of the p53 tumor suppressor, is a target of p53-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Latent and active p53 are identical in conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

DNA-conformation is an important determinant of sequence-specific DNA binding by tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Analysis of the binding of p53 to DNAs containing mismatched and bulged bases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Human p53 binds Holliday junctions strongly and facilitates their cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

DNA bending due to specific p53 and p53 core domain-DNA interactions visualized by electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Tandem duplication. A novel type of triplet repeat instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Long CTG.CAG repeat sequences markedly stimulate intramolecular recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Inverted repeats, stem-loops, and cruciforms: Significance for initiation of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Direct transactivation of c-Ha-Ras gene by p53: evidence for its involvement in p53 transactivation activity and p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

Synergistic transcriptional activation of the MCK promoter by p53: tetramers link separated DNA response elements by DNA looping

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202344200

21 January 2018

Identifiers

DOI

10.1074/JBC.M202344200

1 reference

2 September 2017

1 reference