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Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase.
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4750920
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3 March 2020
title
Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase
(English)
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3 March 2020
author
Didier Trouche
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3
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4750920
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3 March 2020
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Aude Grézy
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1
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4750920
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3 March 2020
Martine Chevillard-Briet
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3 March 2020
Fabrice Escaffit
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4
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3 March 2020
publication date
23 December 2015
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3 March 2020
published in
Molecular Biology of the Cell
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4750920
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3 March 2020
volume
27
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3 March 2020
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4
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3 March 2020
page(s)
599-607
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3 March 2020
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Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged Chromatin
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The histone methyltransferase SUV39H1 suppresses embryonal rhabdomyosarcoma formation in zebrafish
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Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability
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The chromatin remodeler p400 ATPase facilitates Rad51-mediated repair of DNA double-strand breaks
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Deacetylation of H4-K16Ac and heterochromatin assembly in senescence
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Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure
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Histone H4 lysine 12 acetylation regulates telomeric heterochromatin plasticity in Saccharomyces cerevisiae
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The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair
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Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2
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6 September 2017
NuA4-dependent acetylation of nucleosomal histones H4 and H2A directly stimulates incorporation of H2A.Z by the SWR1 complex.
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DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions
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6 September 2017
p21 transcription is regulated by differential localization of histone H2A.Z.
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6 September 2017
To die or not to die: a HAT trick
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6 September 2017
Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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6 September 2017
DNA hypomethylation and human diseases.
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6 September 2017
Distinct roles for the essential MYST family HAT Esa1p in transcriptional silencing
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6 September 2017
Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
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6 September 2017
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM
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6 September 2017
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6 September 2017
The highly conserved and multifunctional NuA4 HAT complex
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6 September 2017
HP1 and the dynamics of heterochromatin maintenance
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6 September 2017
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
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6 September 2017
Heterochromatin: silence is golden.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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6 September 2017
Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein
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6 September 2017
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
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6 September 2017
Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases
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6 September 2017
Cancer-associated alteration of pericentromeric heterochromatin may contribute to chromosome instability
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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6 September 2017
Parallel pathways in RAF-induced senescence and conditions for its reversion.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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6 September 2017
A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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14 September 2017
Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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14 September 2017
Tip60 functions as a potential corepressor of KLF4 in regulation of HDC promoter activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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14 September 2017
Role of the histone acetyl transferase Tip60 in the p53 pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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14 September 2017
Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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27 September 2017
Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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23 June 2018
The histone variant composition of centromeres is controlled by the pericentric heterochromatin state during the cell cycle
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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23 June 2018
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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23 June 2018
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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31 August 2018
Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
retrieved
31 August 2018
The p400/Tip60 ratio is critical for colorectal cancer cell proliferation through DNA damage response pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
retrieved
31 August 2018
Acetylation of the p53 DNA-binding domain regulates apoptosis induction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
retrieved
31 August 2018
Cleavage and cytoplasmic relocalization of histone deacetylase 3 are important for apoptosis progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4750920
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31 August 2018
SUMOylation promotes de novo targeting of HP1α to pericentric heterochromatin
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1091%2FMBC.E15-05-0316
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21 January 2018
Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1091%2FMBC.E15-05-0316
retrieved
21 January 2018
Identifiers
DOI
10.1091/MBC.E15-05-0316
1 reference
stated in
Europe PubMed Central
PMC publication ID
4750920
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26700317%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PMC publication ID
4750920
1 reference
stated in
Europe PubMed Central
PMC publication ID
4750920
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26700317%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
PubMed publication ID
26700317
1 reference
stated in
Europe PubMed Central
PMC publication ID
4750920
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26700317%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 March 2020
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