(Q38421684)

2 September 2017

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title

The functional role of peroxiredoxin 3 in reactive oxygen species, apoptosis, and chemoresistance of cancer cells (English)

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2 September 2017

reactive oxygen species

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Lianqin Li

1

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PubMed ID

25875582

2 September 2017

Ai-Qun Yu

series ordinal

2

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2 September 2017

21 January 2015

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Journal of Cancer Research and Clinical Oncology

2 September 2017

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2 September 2017

141

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2 September 2017

12

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2 September 2017

2071-2077

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https://scigraph.springernature.com/pub.10.1007/s00432-015-1916-3

2 September 2017

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21 January 2018

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Differential expression of peroxiredoxins in prostate cancer: consistent upregulation of PRDX3 and PRDX4

21 January 2018

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21 January 2018

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21 January 2018

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Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes

21 January 2018

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Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin

21 January 2018

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Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria

21 January 2018

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Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine

21 January 2018

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c-Myc enhances colon cancer cell-mediated angiogenesis through the regulation of HIF-1α.

21 January 2018

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FOXO3A regulates peroxiredoxin III expression in human cardiac fibroblasts

21 January 2018

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The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation

21 January 2018

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Oxidation of mitochondrial peroxiredoxin 3 during the initiation of receptor-mediated apoptosis

21 January 2018

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Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells

21 January 2018

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Silencing of peroxiredoxin 3 and peroxiredoxin 5 reveals the role of mitochondrial peroxiredoxins in the protection of human neuroblastoma SH-SY5Y cells toward MPP+

21 January 2018

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Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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MicroRNA-23b downregulates peroxiredoxin III in human prostate cancer

21 January 2018

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Human T cell cyclophilin18 binds to thiol-specific antioxidant protein Aop1 and stimulates its activity

21 January 2018

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FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function

21 January 2018

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Expression of peroxiredoxin 1, 2, 3, and 6 genes in cancer cells during drug resistance formation.

21 January 2018

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Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology

21 January 2018

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Nuclear factor E2-related factor 2 dependent overexpression of sulfiredoxin and peroxiredoxin III in human lung cancer.

21 January 2018

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Cyclophilin a binds to peroxiredoxins and activates its peroxidase activity

21 January 2018

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MiR-383 is downregulated in medulloblastoma and targets peroxiredoxin 3 (PRDX3).

21 January 2018

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Anti-apoptotic role of peroxiredoxin III in cervical cancer cells.

21 January 2018

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RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains

21 January 2018

1 reference

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The role of enoyl-CoA hydratase short chain 1 and peroxiredoxin 3 in PP2-induced apoptosis in human breast cancer MCF-7 cells

21 January 2018

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The biological activity of auranofin: implications for novel treatment of diseases

21 January 2018

1 reference

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Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

The mitochondrial thioredoxin system

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Quercetin induces the expression of peroxiredoxins 3 and 5 via the Nrf2/NRF1 transcription pathway

21 January 2018

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Pag, a putative tumor suppressor, interacts with the Myc Box II domain of c-Myc and selectively alters its biological function and target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Sulfiredoxin Translocation into Mitochondria Plays a Crucial Role in Reducing Hyperoxidized Peroxiredoxin III.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Downregulation of c-MYC protein levels contributes to cancer cell survival under dual deficiency of oxygen and glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Expression of peroxiredoxin and thioredoxin in human lung cancer and paired normal lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Regulation of reactive oxygen species by p53: implications for nitric oxide-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

The mitochondrial antioxidant defence system and its response to oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

The antioxidant function of the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Physiological roles of mitochondrial reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Nonredundant antioxidant defense by multiple two-cysteine peroxiredoxins in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Abrin triggers cell death by inactivating a thiol-specific antioxidant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Hydrogen peroxide induces apoptosis in HeLa cells through mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Mitochondrial peroxiredoxin III is a potential target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Plumbagin induces reactive oxygen species, which mediate apoptosis in human cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Peroxiredoxin overexpression in MCF-7 breast cancer cells and regulation by cell proliferation and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Mammalian antioxidant protein complements alkylhydroperoxide reductase (ahpC) mutation in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Downregulation of the c-MYC target gene, peroxiredoxin III, contributes to arsenic trioxide-induced apoptosis in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Peroxiredoxin III protein expression is associated with platinum resistance in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Peroxiredoxin 3 is resistant to oxidation-induced apoptosis of Hep-3b cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

SP-22 is a thioredoxin-dependent peroxide reductase in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Reduction of cysteine sulfinic acid by sulfiredoxin is specific to 2-cys peroxiredoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Transcriptional up-regulation of FoxM1 in response to hypoxia is mediated by HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Cloning of a housekeeping-type gene (MER5) preferentially expressed in murine erythroleukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Peroxiredoxins, a novel target in cancer radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Abrin and Ricin: New Anti-tumour Substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-015-1916-3

Overexpression of mitochondrial thioredoxin reductase and peroxiredoxin III in hepatocellular carcinomas

21 January 2018

1 reference

12 December 2020

Peroxiredoxin 3 is a novel marker for cell proliferation in cervical cancer

1 reference

12 December 2020

Expression and prognostic significance of human peroxiredoxin isoforms in endometrial cancer

1 reference

12 December 2020

Peroxiredoxins in colorectal neoplasms

1 reference

12 December 2020

Upregulation of peroxiredeoxin III in the hippocampus of acute immobilization stress model rats and the Foxo3a-dependent expression in PC12 cells

1 reference

12 December 2020

Detection and identification of peroxiredoxin 3 as a biomarker in hepatocellular carcinoma by a proteomic approach

1 reference

12 December 2020

Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma

1 reference

12 December 2020

Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis

1 reference

12 December 2020

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

1 reference

12 December 2020

Identification of c-myc responsive genes using rat cDNA microarray.

1 reference

12 December 2020

siRNA targeting of PRDX3 enhances cisplatin‑induced apoptosis in ovarian cancer cells through the suppression of the NF‑κB signaling pathway

1 reference

12 December 2020

Silencing the Peroxiredoxin III gene inhibits cell proliferation in breast cancer.

1 reference

12 December 2020

Expression of human peroxiredoxin isoforms in response to cervical carcinogenesis

1 reference

12 December 2020

Peroxiredoxin proteins protect MCF-7 breast cancer cells from doxorubicin-induced toxicity

1 reference

12 December 2020

Peroxiredoxins in breast carcinoma.

1 reference

12 December 2020

Overexpression of peroxiredoxin in human breast cancer

1 reference

12 December 2020

Antioxidant function of the mitochondrial protein SP-22 in the cardiovascular system

1 reference

12 December 2020

10.1007/S00432-015-1916-3

Identifiers

DOI

1 reference

2 September 2017

1 reference

PubMed ID

25875582