(Q38429571)

English

A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial.

scientific article published on 26 October 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

phase II clinical trial

0 references

0 references

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Christopher W Lee

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Karl Bélanger

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Sanjay C Rao

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Teresa M Petrella

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Richard G Tozer

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Lori Wood

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Kerry J Savage

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Elizabeth A Eisenhauer

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Nancy Wainman

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Lesley Seymour

11

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

publication date

26 October 2007

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

26

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

249-255

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17962907%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

https://scigraph.springernature.com/pub.10.1007/s10637-007-9097-9

0 references

Drug resistance in melanoma: mechanisms, apoptosis, and new potential therapeutic targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Palliative therapy of disseminated malignant melanoma: a systematic review of 41 randomised clinical trials.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One-sample multiple testing procedure for phase II clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor activity of a kinesin inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular dissection of the inhibitor binding pocket of mitotic kinesin Eg5 reveals mutants that confer resistance to antimitotic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of docetaxel in patients with advanced cutaneous malignant melanoma previously untreated with chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II study of taxol in patients with malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis and melanoma chemoresistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of paclitaxel and carboplatin for malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis regulation in tetraploid cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Update results of vindesine as a single agent in the therapy of advanced malignant melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of docetaxel (Taxotere) in patients with metastatic melanoma previously untreated with cytotoxic chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vindesine in patients with metastatic malignant melanoma: a Southwest Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17962907

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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