(Q38441178)

English

Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors-correlation to tumor histopathology and clinical follow-up

scientific article published on 13 August 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors-correlation to tumor histopathology and clinical follow-up (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

author name string

Silke Lassmann

1

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Michael Hennig

2

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Robert Rosenberg

3

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Jörg Nährig

4

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Joachim Schreglmann

5

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Friedemann Krause

6

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Manuela Poignee-Heger

7

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Hjalmar Nekarda

8

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Heinz Höfler

9

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Martin Werner

10

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

13 August 2005

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

International Journal of Colorectal Disease

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

238-247

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Platelet-derived endothelial cell growth factor thymidine phosphorylase in tumour growth and response to therapy

1 reference

https://api.crossref.org/works/10.1007%2FS00384-005-0767-9

21 January 2018

Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS00384-005-0767-9

21 January 2018

Quantitative gene expression analysis in microdissected archival formalin-fixed and paraffin-embedded tumor tissue

1 reference

https://api.crossref.org/works/10.1007%2FS00384-005-0767-9

21 January 2018

Increased thymidylate synthase protein levels are principally associated with proliferation but not cell cycle phase in asynchronous human cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS00384-005-0767-9

21 January 2018

Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases

1 reference

https://api.crossref.org/works/10.1007%2FS00384-005-0767-9

21 January 2018

Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: An immunohistochemical study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenomic dissection of resistance to thymidylate synthase inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphism in the enhancer region of the thymidylate synthase promoter influences the survival of colorectal cancer patients treated with 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term results of single course of adjuvant intraportal chemotherapy for colorectal cancer. Swiss Group for Clinical Cancer Research (SAKK)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between thymidylate synthase expression and survival in colon carcinoma, and determination of appropriate application of 5-fluorouracil by immunohistochemical method

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase activity and thymidylate synthase level are associated with response to 5-fluorouracil in human colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of thymidylate synthase levels in the prognosis and the treatment of patients with colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihydropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of time to recurrence with thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression in stage II and III colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased thymidylate synthase gene expression in liver metastases from colorectal carcinoma: implications for chemotherapeutic options and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High basal level gene expression of thymidine phosphorylase (platelet-derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase expression in colorectal cancer: a prognostic and predictive marker of benefit from adjuvant fluorouracil-based chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of pharmacogenetics and pharmacogenomics in cancer chemotherapy with 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adjuvant chemotherapy for colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants of prognosis and response to therapy in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of thymidine phosphorylase expression in colorectal carcinoma tissues by in situ RT-PCR assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of dihydropyrimidine dehydrogenase in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)- related toxicity compared with controls.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidine phosphorylase activity associated with platelet-derived endothelial cell growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circadian organization of thymidylate synthase activity in normal tissues: a possible basis for 5-fluorouracil chronotherapeutic advantage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphism in the thymidylate synthase promoter enhancer region in colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of CK20 gene and protein expression in colorectal cancer by RT-PCR and immunohistochemistry reveals inter- and intratumour heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combination of dihydropyrimidine dehydrogenase and thymidylate synthase gene expressions in primary tumors as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dihydropyrimidine dehydrogenase activity in normal, inflammatory and tumour tissues of colon and liver in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A systematic overview of chemotherapy effects in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression levels of thymidine phosphorylase and dihydropyrimidine dehydrogenase in various human tumor tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase II study of weekly 24-hour infusion with high-dose fluorouracil with leucovorin in colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activity and expression of thymidine phosphorylase in human solid tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16132996

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00384-005-0767-9

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

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