(Q38442957)

3 September 2017

Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling (English)

1 reference

3 September 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

author name string

Wen-Chin Huang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

Julien Séjourné

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

Amy E Clipperton-Allen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

Damon T Page

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

language of work or name

English

0 references

publication date

1 July 2015

1 reference

3 September 2017

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

volume

35

1 reference

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15 May 2020

issue

28

1 reference

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15 May 2020

page(s)

10252-10267

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describes a project that uses

15 May 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

S-100β protein is upregulated in astrocytes and motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis

1 reference

12 December 2020

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

1 reference

12 December 2020

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

1 reference

12 December 2020

Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia

1 reference

12 December 2020

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

1 reference

12 December 2020

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

1 reference

12 December 2020

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

1 reference

12 December 2020

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

1 reference

12 December 2020

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.

1 reference

12 December 2020

PTEN: a new twist on β-catenin?

1 reference

12 December 2020

PTEN in neural precursor cells: regulation of migration, apoptosis, and proliferation

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12 December 2020

Regulation of cerebral cortical size by control of cell cycle exit in neural precursors

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12 December 2020

Abnormal early brain development in autism

1 reference

12 December 2020

Cortical excitatory neurons and glia, but not GABAergic neurons, are produced in the Emx1-expressing lineage.

1 reference

12 December 2020

Cerebral lobes in autism: early hyperplasia and abnormal age effects

1 reference

12 December 2020

PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.

1 reference

12 December 2020

Anti-human Olig2 antibody as a useful immunohistochemical marker of normal oligodendrocytes and gliomas

1 reference

12 December 2020

1 reference

12 December 2020

Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo

1 reference

12 December 2020

Neuroglial activation and neuroinflammation in the brain of patients with autism

1 reference

12 December 2020

bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.

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12 December 2020

Localized enlargement of the frontal cortex in early autism

1 reference

12 December 2020

Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain.

1 reference

12 December 2020

Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

1 reference

12 December 2020

Nuclear-cytoplasmic partitioning of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) differentially regulates the cell cycle and apoptosis

1 reference

12 December 2020

Magnetic resonance imaging and head circumference study of brain size in autism: birth through age 2 years

1 reference

12 December 2020

Modeling early cortical serotonergic deficits in autism

1 reference

12 December 2020

GSK3 beta mediates suppression of cyclin D2 expression by tumor suppressor PTEN.

1 reference

12 December 2020

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

1 reference

12 December 2020

PTEN, a general negative regulator of cyclin D expression

1 reference

12 December 2020

Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly

1 reference

12 December 2020

Cerebral cortical gray matter overgrowth and functional variation of the serotonin transporter gene in autism.

1 reference

12 December 2020

Mapping Early Brain Development in Autism

1 reference

12 December 2020

CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes

1 reference

12 December 2020

Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior

1 reference

12 December 2020

The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.

1 reference

12 December 2020

The glial nature of embryonic and adult neural stem cells

1 reference

12 December 2020

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

1 reference

12 December 2020

Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism

1 reference

12 December 2020

Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly.

1 reference

12 December 2020

Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism.

1 reference

12 December 2020

A sensitive and bright single-cell resolution live imaging reporter of Wnt/ß-catenin signaling in the mouse.

1 reference

12 December 2020

Transcriptomic analysis of autistic brain reveals convergent molecular pathology

1 reference

12 December 2020

In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics

1 reference

12 December 2020

Neuron number and size in prefrontal cortex of children with autism

1 reference

12 December 2020

Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages

1 reference

12 December 2020

Development and characterization of NEX- Pten, a novel forebrain excitatory neuron-specific knockout mouse.

1 reference

12 December 2020

PTEN signaling in autism spectrum disorders

1 reference

12 December 2020

Wnt/β-catenin signaling and disease

1 reference

12 December 2020

Diagnostic exome sequencing in persons with severe intellectual disability

1 reference

12 December 2020

Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders

1 reference

12 December 2020

Macrocephaly as a clinical indicator of genetic subtypes in autism

1 reference

12 December 2020

Microglial activation in young adults with autism spectrum disorder.

1 reference

12 December 2020

Compared to what? Early brain overgrowth in autism and the perils of population norms

1 reference

12 December 2020

The glial perspective of autism spectrum disorders

1 reference

12 December 2020

Altered glial marker expression in autistic post-mortem prefrontal cortex and cerebellum

1 reference

12 December 2020

Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests

1 reference

12 December 2020

A genotype-first approach to defining the subtypes of a complex disease

1 reference

12 December 2020

A new intellectual disability syndrome caused by CTNNB1 haploinsufficiency

1 reference

12 December 2020

Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism

1 reference

12 December 2020

Overproduction of upper-layer neurons in the neocortex leads to autism-like features in mice.

1 reference

12 December 2020

Delayed maturation of the frontal cortex in childhood autism.

1 reference

12 December 2020

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

12 December 2020

Apoptosis in the developing CNS.

1 reference

12 December 2020

A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

1 reference

12 December 2020

Regional brain enlargement in autism: a magnetic resonance imaging study.

1 reference

12 December 2020

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

12 December 2020

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

12 December 2020

MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines

1 reference

12 December 2020

PTEN mutations in gliomas and glioneuronal tumors.

1 reference

12 December 2020

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

12 December 2020

10.1523/JNEUROSCI.5272-14.2015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6605343&resulttype=core&format=json