(Q38472428)

3 September 2017

title

Seven essential questions on G-quadruplexes (English)

1 reference

3 September 2017

Sebastian L B König

1

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3 September 2017

Amanda C Evans

series ordinal

2

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3 September 2017

Julian L Huppert

series ordinal

3

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3 September 2017

publication date

1 August 2010

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3 September 2017

published in

Biomolecular concepts

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3 September 2017

volume

1

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3 September 2017

issue

2

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3 September 2017

page(s)

197-213

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Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

3 September 2017

cites work

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Helix formation by guanylic acid

21 January 2018

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Kinetics of tetramolecular quadruplexes

21 January 2018

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The selectivity for K+ versus Na+ in DNA quadruplexes is dominated by relative free energies of hydration: a thermodynamic analysis by 1H NMR.

21 January 2018

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Cation-dependent transition between the quadruplex and Watson-Crick hairpin forms of d(CGCG3GCG)

21 January 2018

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https://api.crossref.org/works/10.1515%2FBMC.2010.011

Effect of ions on the polymorphism, effective charge, and stability of human telomeric DNA. Photon correlation spectroscopy and circular dichroism studies.

21 January 2018

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Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes

21 January 2018

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DNA G-quartets in a 1.86 A resolution structure of an Oxytricha nova telomeric protein-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The crystal structure of a parallel-stranded guanine tetraplex at 0.95 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Structure of a G-quadruplex-ligand complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Crystal structure of parallel quadruplexes from human telomeric DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Formation of an interlocked quadruplex dimer by d(GGGT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Two-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Two-repeat Tetrahymena telomeric d(TGGGGTTGGGGT) Sequence interconverts between asymmetric dimeric G-quadruplexes in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The solution structure of d(G(4)T(4)G(3))(2): a bimolecular G-quadruplex with a novel fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

d(G3T4G3) forms an asymmetric diagonally looped dimeric quadruplex with guanosine 5'-syn-syn-anti and 5'-syn-anti-anti N-glycosidic conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Small change in a G-rich sequence, a dramatic change in topology: new dimeric G-quadruplex folding motif with unique loop orientations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Solution structure of the Tetrahymena telomeric repeat d(T2G4)4 G-tetraplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

A double chain reversal loop and two diagonal loops define the architecture of a unimolecular DNA quadruplex containing a pair of stacked G(syn)-G(syn)-G(anti)-G(anti) tetrads flanked by a G-(T-T) Triad and a T-T-T triple

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Quadruplex DNA: sequence, topology and structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Quadruplex structures in nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Loop-length-dependent folding of G-quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Following G-quartet formation by UV-spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Circular dichroism of quadruplex DNAs: applications to structure, cation effects and ligand binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Measured and calculated CD spectra of G-quartets stacked with the same or opposite polarities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Prevalence of quadruplexes in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Bioinformatics approaches to quadruplex sequence location

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Computational approaches to the detection and analysis of sequences with intramolecular G-quadruplex forming potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

21 January 2018

Hunting G-quadruplexes

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Influence of loop size on the stability of intramolecular DNA quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Solution structure of a parallel-stranded G-quadruplex DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The structure of telomeric DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

G-quadruplex DNA structures--variations on a theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Guanine quartet structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Thermodynamics of G-tetraplex formation by telomeric DNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Hybridization of PNA to structured DNA targets: quadruplex invasion and the overhang effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

NMR structure refinement and dynamics of the K+-[d(G3T4G3)]2 quadruplex via particle mesh Ewald molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Cloning and expression of genes for the Oxytricha telomere-binding protein: specific subunit interactions in the telomeric complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The beta subunit of Oxytricha telomere-binding protein promotes G-quartet formation by telomeric DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Predicting and understanding the stability of G-quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Genome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

In vivo veritas: using yeast to probe the biological functions of G-quadruplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

G-quadruplex structures: in vivo evidence and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

G-quadruplexes in promoters throughout the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Direct visualization of G-quadruplexes in DNA using atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

A conserved G4 DNA binding domain in RecQ family helicases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Spectrum of mutational events in the absence of DOG-1/FANCJ in Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Evidence of genome-wide G4 DNA-mediated gene expression in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

G-quadruplexes: the beginning and end of UTRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Inhibition of telomerase by G-quartet DNA structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The relationship of potential G-quadruplex sequences in cis-upstream regions of the human genome to SP1-binding elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Paclitaxel activation of the GADD153 promoter through a cellular injury response element containing an essential Sp1 binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

DNA tetraplex formation in the control region of c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Putative DNA quadruplex formation within the human c-kit oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The human side of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Genome-wide computational and expression analyses reveal G-quadruplex DNA motifs as conserved cis-regulatory elements in human and related species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Highly prevalent putative quadruplex sequence motifs in human DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

G-quadruplex nucleic acids as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Anticancer activity of CX-3543: a direct inhibitor of rRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

A hitchhiker's guide to G-quadruplex ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Structural basis for binding of porphyrin to human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Structural basis of DNA quadruplex recognition by an acridine drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Topology conservation and loop flexibility in quadruplex-drug recognition: crystal structures of inter- and intramolecular telomeric DNA quadruplex-drug complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Fluorescent sensor for monitoring structural changes of G-quadruplexes and detection of potassium ion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Crystal violet-G-quadruplex complexes as fluorescent sensors for homogeneous detection of potassium ion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Reversible electronic nanoswitch based on DNA G-quadruplex conformation: a platform for single-step, reagentless potassium detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

DNA duplex-quadruplex exchange as the basis for a nanomolecular machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

A biomimetic potassium responsive nanochannel: G-quadruplex DNA conformational switching in a synthetic nanopore

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Guanosine hydrogen-bonded scaffolds: a new way to control the bottom-up realisation of well-defined nanoarchitectures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

The sodium ions inside a lipophilic G-quadruplex channel as probed by solid-state (23)Na NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Selection of a Suppressor Mutation That Restores Affinity of an Oligonucleotide Inhibitor for Thrombin Using in Vitro Genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Aptameric enzyme subunit for homogeneous protein sensing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Cancer-selective antiproliferative activity is a general property of some G-rich oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

A tetrameric DNA structure with protonated cytosine.cytosine base pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into an i-motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Centromeric pyrimidine strands fold into an intercalated motif by forming a double hairpin with a novel T:G:G:T tetrad: solution structure of the d(TCCCGTTTCCA) dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Multistranded DNA structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

Targeting telomeres and telomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

RELATIVE STABILITY OF QUADRUPLEXES CONTAINING DIFFERENT NUMBER OF G-TETRADS

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBMC.2010.011

21 January 2018

Identifiers

DOI

10.1515/BMC.2010.011

1 reference

3 September 2017

1 reference