(Q38478308)

3 September 2017

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title

The dendrimer paradox--high medical expectations but poor clinical translation (English)

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3 September 2017

Sonke Svenson

1

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3 September 2017

language of work or name

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1 June 2015

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3 September 2017

published in

Chemical Society Reviews

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3 September 2017

volume

44

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3 September 2017

issue

12

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3 September 2017

page(s)

4131-4144

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"Cascade"- and "Nonskid-Chain-like" Syntheses of Molecular Cavity Topologies

3 September 2017

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Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives

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21 January 2018

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Dendritic polymer macromolecular carriers for drug delivery

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Liposomal drug delivery systems: from concept to clinical applications

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21 January 2018

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Receptor targeted polymers, dendrimers, liposomes: which nanocarrier is the most efficient for tumor-specific treatment and imaging?

21 January 2018

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A comparison of changes to doxorubicin pharmacokinetics, antitumor activity, and toxicity mediated by PEGylated dendrimer and PEGylated liposome drug delivery systems.

21 January 2018

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Dendrimer, liposomes, carbon nanotubes and PLGA nanoparticles: one platform assessment of drug delivery potential

21 January 2018

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Design considerations for PAMAM dendrimer therapeutics

21 January 2018

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Theranostics: are we there yet?

21 January 2018

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Multivalent polymers for drug delivery and imaging: the challenges of conjugation

21 January 2018

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Dendrimers as biopharmaceuticals: synthesis and properties

21 January 2018

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21 January 2018

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21 January 2018

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Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

21 January 2018

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21 January 2018

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Click dendrimers and triazole-related aspects: catalysts, mechanism, synthesis, and functions. A bridge between dendritic architectures and nanomaterials

21 January 2018

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"Clicking" on/with polymers: a rapidly expanding field for the straightforward preparation of novel macromolecular architectures.

21 January 2018

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Strain-promoted alkyne azide cycloaddition for the functionalization of poly(amide)-based dendrons and dendrimers.

21 January 2018

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Cu-free click cycloaddition reactions in chemical biology

21 January 2018

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Reactions under the click chemistry philosophy employed in supramolecular and mechanostereochemical systems

21 January 2018

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Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

21 January 2018

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Accelerated Growth of Dendrimers via Thiol−Ene and Esterification Reactions

21 January 2018

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Efficient and accelerated growth of multifunctional dendrimers using orthogonal thiol-ene and SN2 reactions.

21 January 2018

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Synthesis of nanoparticle-cored dendrimers by convergent dendritic functionalization of monolayer-protected nanoparticles

21 January 2018

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Design of polymeric nanoparticles for biomedical delivery applications

21 January 2018

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Development of self-immolative dendrimers for drug delivery and sensing

21 January 2018

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Degradable self-assembling dendrons for gene delivery: experimental and theoretical insights into the barriers to cellular uptake

21 January 2018

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Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to biomedically relevant lectins.

21 January 2018

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Toward the next-generation drug delivery vehicle: synthesis of a dendrimer with four orthogonally reactive groups

21 January 2018

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Design, synthesis and biological assessment of a triazine dendrimer with approximately 16 Paclitaxel groups and 8 PEG groups.

21 January 2018

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Construction of a well-defined multifunctional dendrimer for theranostics

21 January 2018

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Janus-type dendrimer-like poly(ethylene oxide)s

21 January 2018

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Designing macromolecules for therapeutic applications: polyester dendrimer-poly(ethylene oxide) "bow-tie" hybrids with tunable molecular weight and architecture

21 January 2018

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Amphiphilic cationic carbosilane-PEG dendrimers: synthesis and applications in gene therapy.

21 January 2018

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Bifunctional dendrimers: from robust synthesis and accelerated one-pot postfunctionalization strategy to potential applications

21 January 2018

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The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

21 January 2018

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The lower-generation polypropylenimine dendrimers are effective gene-transfer agents.

21 January 2018

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Facile access to internally functionalized dendrimers through efficient and orthogonal click reactions.

21 January 2018

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Shape effects of filaments versus spherical particles in flow and drug delivery

21 January 2018

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The effects of polymeric nanostructure shape on drug delivery

21 January 2018

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Filamentous, mixed micelles of triblock copolymers enhance tumor localization of indocyanine green in a murine xenograft model

21 January 2018

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Dendron-mediated self-assembly, disassembly, and self-organization of complex systems

21 January 2018

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An expeditious multigram-scale synthesis of lysine dendrigraft (DGL) polymers by aqueous N-carboxyanhydride polycondensation

21 January 2018

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In vitro transfection mediated by dendrigraft poly(L-lysines): the effect of structure and molecule size.

21 January 2018

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A leptin derived 30-amino-acid peptide modified pegylated poly-L-lysine dendrigraft for brain targeted gene delivery

21 January 2018

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Stealth polymeric vesicles via metal-free click coupling

21 January 2018

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Drug-induced morphology switch in drug delivery systems based on poly(2-oxazoline)s.

21 January 2018

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Thiol−Ene Click Functionalization and Subsequent Polymerization of 2-Oxazoline Monomers

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Hyperbranched polymers: Phase behavior and new applications in the field of chemical engineering

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Hyperbranched polymers: from synthesis to applications

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Dendritic polyglycerols for biomedical applications

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Biofunctional nanosystems based on dendritic polymers

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Hyperbranched polyglycerols as trimodal imaging agents: design, biocompatibility, and tumor uptake.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Development of enzymatically cleavable prodrugs derived from dendritic polyglycerol

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Dendronized polymers—building a new bridge from molecules to nanoscopic objects

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Polymer therapeutics: Top 10 selling pharmaceuticals - what next?

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

AB3 building blocks for the synthesis of polyester dendrimers

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

Hyperbranched polydendrons: a new controlled macromolecular architecture with self-assembly in water and organic solvents

21 January 2018

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https://api.crossref.org/works/10.1039%2FC5CS00288E

21 January 2018

Identifiers

DOI

10.1039/C5CS00288E

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3 September 2017

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