(Q38495363)

English

Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation

scientific article published on 17 March 2009

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

1 reference

based on heuristic

inferred from title

Parkinson's disease

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author name string

Minho Moon

1

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Hyo Geun Kim

2

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Europe PubMed Central

PubMed publication ID

3 September 2017

Lakkyong Hwang

3

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Europe PubMed Central

PubMed publication ID

3 September 2017

Ji-Hyung Seo

4

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Europe PubMed Central

PubMed publication ID

3 September 2017

Sehee Kim

5

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Europe PubMed Central

PubMed publication ID

3 September 2017

Sunyoung Hwang

6

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Soonyong Kim

7

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Dahm Lee

8

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Hyunju Chung

9

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Myung Sook Oh

10

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Kyung-Tae Lee

11

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Seungjoon Park

12

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

publication date

17 March 2009

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Europe PubMed Central

PubMed publication ID

3 September 2017

Neurotoxicity Research

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Europe PubMed Central

PubMed publication ID

3 September 2017

15

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Europe PubMed Central

PubMed publication ID

3 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

332-347

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12640-009-9037-X

21 January 2018

Ghrelin antagonizes MPTP-induced neurotoxicity to the dopaminergic neurons in mouse substantia nigra

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin: structure and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenic role of glial cells in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of redox factor-1 negatively regulates NO synthesis and apoptosis in LPS-stimulated RAW 264.7 macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Art and artifice in the science of histology. 1933.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin protects cortical neuron against focal ischemia/reperfusion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin amplifies dopamine signaling by cross talk involving formation of growth hormone secretagogue receptor/dopamine receptor subtype 1 heterodimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatography/tandem mass spectrometric assay for the simultaneous measurement of dopamine, norepinephrine, 5-hydroxytryptamine and cocaine in biological samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of microglia in the central nervous system's immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular pathology of Parkinson's disease: astrocytes, microglia and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical pathophysiology of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothalamic/pituitary-axis of the spontaneous dwarf rat: autofeedback regulation of growth hormone (GH) includes suppression of GH releasing-hormone receptor messenger ribonucleic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effect of vasoactive intestinal peptide (VIP) in a mouse model of Parkinson's disease by blocking microglial activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental models of Parkinson's disease: insights from many models

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide inhibitors of caspase-3-like proteases attenuate 1-methyl-4-phenylpyridinum-induced toxicity of cultured fetal rat mesencephalic dopamine neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal MPTP binding in parkinsonian substantial nigra: evidence for extraneuronal toxin conversion in human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkinson's disease: current and future challenges

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin-induced growth hormone secretion in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of inducible nitric oxide synthase protects against MPTP toxicity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

17Beta-estradiol reduces nitrotyrosine immunoreactivity and increases SOD1 and SOD2 immunoreactivity in nigral neurons in male mice following MPTP insult

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines and the nervous system. I: Expression and recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3 beta and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygen-glucose deprivation-induced apoptosis in primary rat cortical neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia: Intrinsic immuneffector cell of the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midbrain dopaminergic neurons in the mouse: computer-assisted mapping

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial and metabolic toxicity of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Etiology and pathogenesis of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia as mediators of inflammatory and degenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of MPTP toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of glial cells in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatography/tandem mass spectrometry assay for the determination of 1-methyl-4-phenyl pyridinium (MPP+) in brain tissue homogenates

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia: a sensor for pathological events in the CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fasting-induced changes in the hypothalamic-pituitary-GH axis in the absence of GH expression: lessons from the spontaneous dwarf rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nonpeptidyl growth hormone secretagogue

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of ghrelin receptor mRNA in the rat and the mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method

1 reference

https://pubmed.ncbi.nlm.nih.gov/19384567

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12640-009-9037-X

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 September 2017

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