(Q38497862)

3 September 2017

title

AT-rich islands in genomic DNA as a novel target for AT-specific DNA-reactive antitumor drugs (English)

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3 September 2017

Woynarowski JM

1

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3 September 2017

Trevino AV

2

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3 September 2017

Rodriguez KA

3

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3 September 2017

Hardies SC

4

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3 September 2017

Benham CJ

5

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3 September 2017

language of work or name

English

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publication date

3 August 2001

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Journal of Biological Chemistry

3 September 2017

published in

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3 September 2017

volume

276

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3 September 2017

issue

44

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3 September 2017

page(s)

40555-40566

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DNA sequence specificity of antitumor agents. Oncogenes as possible targets for cancer therapy

3 September 2017

cites work

1 reference

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Mapping of DNA alkylation sites induced by adozelesin and bizelesin in human cells by ligation-mediated polymerase chain reaction.

21 January 2018

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In vitro and in vivo DNA bonding by the CC-1065 analog U-73975

21 January 2018

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Induction of AT-specific DNA-interstrand crosslinks by bizelesin in genomic and simian virus 40 DNA.

21 January 2018

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Effects of bizelesin (U-77779), a bifunctional alkylating minor groove agent, on genomic and simian virus 40 DNA.

21 January 2018

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Tallimustine in advanced previously untreated colorectal cancer, a phase II study

21 January 2018

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Phase I trial of Adozelesin using the treatment schedule of daily x5 every 3 weeks

21 January 2018

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Phase I study of adozelesin administered by 24-hour continuous intravenous infusion

21 January 2018

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21 January 2018

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21 January 2018

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A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and in vitro amplification of DNA

21 January 2018

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Exact method for numerically analyzing a model of local denaturation in superhelically stressed DNA

21 January 2018

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Sites of predicted stress-induced DNA duplex destabilization occur preferentially at regulatory loci

21 January 2018

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Stress-induced duplex DNA destabilization in scaffold/matrix attachment regions

21 January 2018

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Biological significance of unwinding capability of nuclear matrix-associating DNAs

21 January 2018

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Sequence dependence of DNA conformational flexibility

21 January 2018

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21 January 2018

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Mathematical model to predict regions of chromatin attachment to the nuclear matrix

21 January 2018

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Identification of domains mediating transcription activation, repression, and inhibition in the paired-related homeobox protein, Prx2 (S8).

21 January 2018

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Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

21 January 2018

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Variant mapping of the Apo(B) AT rich minisatellite. Dependence on nucleotide sequence of the copy number variations. Instability of the non-canonical alleles

21 January 2018

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Fragile sites and minisatellite repeat instability

21 January 2018

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A new rare distamycin A-inducible fragile site, fra(11) (p15.1), found in two acute nonlymphocytic leukemia (ANLL) patients with t(7;11)(p15-p13;p15).

21 January 2018

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Heritable fragile sites and cancer: fra(16)(q22) in lymphocytes of an acute nonlymphocytic leukemia patient with inv(16)(p13q22).

21 January 2018

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Association between DNA cleavage during apoptosis and regions of chromatin replication

21 January 2018

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Analysis of the chicken DNA fragments that contain structural sites of attachment to the nuclear matrix: DNA-matrix interactions and replication

21 January 2018

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Heterogeneity of eukaryotic replicons, replicon clusters, and replication foci

21 January 2018

1 reference

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Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Solution conformation of a bizelesin A-tract duplex adduct: DNA-DNA cross-linking of an A-tract straightens out bent DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Effects of bizelesin (U-77,779), a bifunctional alkylating minor groove binder, on replication of genomic and simian virus 40 DNA in BSC-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3' hypervariable region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Mechanisms of DNA sequence selective alkylation of guanine-N7 positions by nitrogen mustards

21 January 2018

1 reference

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Tallimustine lesions in cellular DNA are AT sequence-specific but not region-specific

21 January 2018

1 reference

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Interlaboratory validation of a new assay for DNA-protein crosslinks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Region-specific DNA damage by AT-specific DNA-reactive drugs is predicted by drug binding specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Energetics of the strand separation transition in superhelical DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Duplex destabilization in superhelical DNA is predicted to occur at specific transcriptional regulatory regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Fragile sites still breaking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

Analysis of telomeric repeats and telomerase activity in human colon carcinoma cells with gene amplification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

DNA damage induced by seven N-nitroso compounds in primary cultures of human and rat kidney cells

21 January 2018

1 reference

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Influence of drug binding on DNA flexibility: a normal mode analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103390200

21 January 2018

Identifiers

DOI

10.1074/JBC.M103390200

1 reference

3 September 2017

1 reference