(Q38501757)

3 September 2017

title

Variations in aggrecan localization and gene expression patterns characterize increasing stages of human intervertebral disk degeneration (English)

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3 September 2017

Helen E Gruber

1

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3 September 2017

Gretchen L Hoelscher

2

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3 September 2017

Jane A Ingram

3

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3 September 2017

Synthia Bethea

4

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3 September 2017

Natalia Zinchenko

5

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3 September 2017

Edward N Hanley

6

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3 September 2017

publication date

12 June 2011

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Experimental and Molecular Pathology

3 September 2017

published in

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3 September 2017

volume

91

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3 September 2017

issue

2

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3 September 2017

page(s)

534-539

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Normoxic stabilization of HIF-1alpha drives glycolytic metabolism and regulates aggrecan gene expression in nucleus pulposus cells of the rat intervertebral disk

3 September 2017

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PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc

7 January 2021

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Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc

7 January 2021

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Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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A comparative analysis of the differential spatial and temporal distributions of the large (aggrecan, versican) and small (decorin, biglycan, fibromodulin) proteoglycans of the intervertebral disc

7 January 2021

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Aggrecan, versican and type VI collagen are components of annular translamellar crossbridges in the intervertebral disc.

7 January 2021

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Aggrecanases and aggrecanase-generated fragments in the human intervertebral disc at early and advanced stages of disc degeneration

7 January 2021

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Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degeneration

7 January 2021

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Is degenerative disk disease genetically determined?

7 January 2021

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Identifying differentially expressed genes using false discovery rate controlling procedures

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Aggrecan turnover in human intervertebral disc as determined by the racemization of aspartic acid

7 January 2021

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7 January 2021

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Association Between the Aggrecan Gene Variable Number of Tandem Repeats Polymorphism and Intervertebral Disc Degeneration

7 January 2021

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Aggrecan degradation in human intervertebral disc and articular cartilage

7 January 2021

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TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc

7 January 2021

1 reference

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The occurrence of anular tears and their relation to lifetime back pain history: a cadaveric study using barium sulfate discography.

7 January 2021

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Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing

7 January 2021

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Dwarfism and age-associated spinal degeneration of heterozygote cmd mice defective in aggrecan

7 January 2021

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Advanced glycation end-products downregulating intervertebral disc cell production of proteoglycans in vitro.

7 January 2021

1 reference

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10.1016/J.YEXMP.2011.06.001

7 January 2021

Identifiers

DOI

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3 September 2017

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