(Q38507467)

English

Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-beta-1b treatment in relapsing remitting MS.

scientific article published on February 2010

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scholarly article

1 reference

Europe PubMed Central

3 September 2017

Long-term genome-wide blood RNA expression profiles yield novel molecular response candidates for IFN-beta-1b treatment in relapsing remitting MS. (English)

1 reference

Europe PubMed Central

3 September 2017

author name string

Robert H Goertsches

1

1 reference

Europe PubMed Central

3 September 2017

Michael Hecker

2

1 reference

Europe PubMed Central

3 September 2017

Dirk Koczan

3

1 reference

Europe PubMed Central

3 September 2017

Pablo Serrano-Fernandez

4

1 reference

Europe PubMed Central

3 September 2017

Steffen Moeller

5

1 reference

Europe PubMed Central

3 September 2017

Hans-Juergen Thiesen

6

1 reference

Europe PubMed Central

3 September 2017

Uwe K Zettl

7

1 reference

Europe PubMed Central

3 September 2017

publication date

1 February 2010

1 reference

Europe PubMed Central

3 September 2017

Pharmacogenomics

1 reference

Europe PubMed Central

3 September 2017

11

1 reference

Europe PubMed Central

3 September 2017

2

1 reference

Europe PubMed Central

3 September 2017

147-161

1 reference

Europe PubMed Central

3 September 2017

The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Toward the development of rational therapies in multiple sclerosis: what is on the horizon?

1 reference

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21 January 2018

Basic and escalating immunomodulatory treatments in multiple sclerosis: current therapeutic recommendations

1 reference

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21 January 2018

Systems biology and its application to the understanding of neurological diseases.

1 reference

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21 January 2018

Systems biology approaches for the study of multiple sclerosis

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Novel interferon-beta-induced gene expression in peripheral blood cells.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Microarray analysis identifies interferon beta-regulated genes in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Genomic effects of IFN-beta in multiple sclerosis patients

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Understanding autoimmune mechanisms in multiple sclerosis using gene expression microarrays: treatment effect and cytokine-related pathways.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Microarray detection of E2F pathway activation and other targets in multiple sclerosis peripheral blood mononuclear cells

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Gene expression profiling of relevant biomarkers for treatment evaluation in multiple sclerosis

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Transcription-based prediction of response to IFNbeta using supervised computational methods

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

A network analysis of the human T-cell activation gene network identifies JAGGED1 as a therapeutic target for autoimmune diseases

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Gene expression profiles reveal homeostatic dynamics during interferon-beta therapy in multiple sclerosis

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Genome-wide network analysis reveals the global properties of IFN-beta immediate transcriptional effects in humans

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

IFN-beta1b induces transient and variable gene expression in relapsing-remitting multiple sclerosis patients independent of neutralizing antibodies or changes in IFN receptor RNA expression.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Biological response genes after single dose administration of interferon beta-1b to healthy male volunteers.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Genomic effects of once-weekly, intramuscular interferon-beta1a treatment after the first dose and on chronic dosing: Relationships to 5-year clinical outcomes in multiple sclerosis patients

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Monitoring of multiple sclerosis immunotherapy: from single candidates to biomarker networks.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Interferons at age 50: past, current and future impact on biomedicine

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Pharmacogenomics of interferon-beta therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Aberrant transcriptional regulatory network in T cells of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Differing immunogenic potentials of interferon beta preparations in multiple sclerosis patients

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Integrative modeling of transcriptional regulation in response to antirheumatic therapy

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

The utility of MAS5 expression summary and detection call algorithms

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Novel definition files for human GeneChips based on GeneAnnot

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

GeneAnnot: comprehensive two-way linking between oligonucleotide array probesets and GeneCards genes.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Gene ontology: tool for the unification of biology

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Using GOstats to test gene lists for GO term association

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Cytoscape: a software environment for integrated models of biomolecular interaction networks

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Biological responsiveness to first injections of interferon-beta in patients with multiple sclerosis.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

A family of fatty acid binding receptors

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Free fatty acid receptors and drug discovery

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Targeting signal transduction as a strategy to treat inflammatory diseases.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Biological markers of interferon-beta therapy: comparison among interferon-stimulated genes MxA, TRAIL and XAF-1.

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Absence of MxA induction by interferon beta in patients with MS reflects complete loss of bioactivity

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Pharmacogenomics of Type I interferon therapy: a survey of response-modifying genes

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Pharmacogenomics of the response to IFN-beta in multiple sclerosis: ramifications from the first genome-wide screen

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

A data integration methodology for systems biology

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Charting protein complexes, signaling pathways, and networks in the immune system

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.152

21 January 2018

Identifiers

10.2217/PGS.09.152

1 reference

Europe PubMed Central

3 September 2017

1 reference

Europe PubMed Central

3 September 2017

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