(Q38511971)

English

Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus

scientific article

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scholarly article

1 reference

Europe PubMed Central

3 September 2017

Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus (English)

1 reference

Europe PubMed Central

3 September 2017

Hepatitis B virus

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

bioavailability

1 reference

based on heuristic

inferred from title

author name string

Frick LW

1

1 reference

Europe PubMed Central

3 September 2017

St John L

2

1 reference

Europe PubMed Central

3 September 2017

Taylor LC

3

1 reference

Europe PubMed Central

3 September 2017

Painter GR

4

1 reference

Europe PubMed Central

3 September 2017

Furman PA

5

1 reference

Europe PubMed Central

3 September 2017

Liotta DC

6

1 reference

Europe PubMed Central

3 September 2017

Furfine ES

7

1 reference

Europe PubMed Central

3 September 2017

Nelson DJ

8

1 reference

Europe PubMed Central

3 September 2017

language of work or name

0 references

publication date

1 November 1993

1 reference

Europe PubMed Central

3 September 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

3 September 2017

37

1 reference

Europe PubMed Central

3 September 2017

11

1 reference

Europe PubMed Central

3 September 2017

2285-2292

1 reference

Europe PubMed Central

3 September 2017

Fitting curves to data using nonlinear regression: a practical and nonmathematical review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Pharmacokinetics of 3'-azido-3'-deoxythymidine and its catabolites and interactions with probenecid in rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Two-Drug Combinations of Zidovudine, Didanosine, and Recombinant Interferon- A Inhibit Replication of Zidovudine-Resistant Human Immunodeficiency Virus Type 1 Synergistically In Vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Synergistic inhibition of replication of human immunodeficiency virus type 1, including that of a zidovudine-resistant isolate, by zidovudine and 2',3'-dideoxycytidine in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Evidence for conversion of 5-fluorocytosine to 5-fluorouracil in humans: possible factor in 5-fluorocytosine clinical toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

6 September 2017

Flavin-containing monooxygenases: catalytic mechanism and substrate specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

14 September 2017

Structure-activity relationship of ligands of the pyrimidine nucleoside phosphorylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

14 September 2017

Physiologically Based Pharmacokinetic Modeling: Principles and Applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

14 September 2017

The disposition and metabolism of 2',3'-dideoxycytidine, an in vitro inhibitor of human T-lymphotrophic virus type III infectivity, in mice and monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

An in vitro system for screening anti-hepatitis B virus drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

Disposition in animals of a new anti-HIV agent: 2',3'-didehydro-3'-deoxythymidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

Probenecid enhances central nervous system uptake of 2',3'-dideoxyinosine by inhibiting cerebrospinal fluid efflux.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

Competitive inhibition of zidovudine clearance by probenecid during continuous coadministration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

Simple and Reliable Method for Serial Sampling of Blood from Rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

Similarity of renal glomerular hemodynamics in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

23 June 2018

Dose-ranging pharmacokinetics of zidovudine (azidothymidine) in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192380

31 August 2018

Renal secretion of 3'-azido-3'-deoxythymidine by the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal transepithelial transport of nucleosides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and saturable renal tubular secretion of zidovudine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of zidovudine pharmacokinetics by probenecid in patients with AIDS or AIDS-related complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of probenecid on the renal and nonrenal clearances of zidovudine and its distribution into cerebrospinal fluid in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative pharmacokinetics of 3'-azido-3'-deoxythymidine (AZT) and 3'-azido-2',3'-dideoxyuridine (AZddU) in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of 2',3'-dideoxycytidine in rats: application to interspecies scale-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain and cerebrospinal fluid uptake of zidovudine (AZT) in rats after intravenous injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/8285607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.37.11.2285

1 reference

Europe PubMed Central

3 September 2017

release_4lp6k6nvqngjhgye334id2d3rq

1 reference

https://api.fatcat.wiki/v0/release/4lp6k6nvqngjhgye334id2d3rq

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

3 September 2017

1 reference

Europe PubMed Central

3 September 2017

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