(Q38544976)

4 September 2017

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title

Adaptive Immunity in Schizophrenia: Functional Implications of T Cells in the Etiology, Course and Treatment (English)

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4 September 2017

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Monojit Debnath

1

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4 September 2017

publication date

11 July 2015

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Journal of Neuroimmune Pharmacology

4 September 2017

published in

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4 September 2017

volume

10

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4 September 2017

issue

4

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4 September 2017

page(s)

610-619

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https://scigraph.springernature.com/pub.10.1007/s11481-015-9626-9

4 September 2017

exact match

0 references

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Role of dopamine in malignant tumor growth

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D1 and D2 dopamine receptor-mediated inhibition of activated normal T cell proliferation is lost in jurkat T leukemic cells

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T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines

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Clinical review: immunomodulatory effects of dopamine in general inflammation

21 January 2018

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Dopamine by itself activates either D2, D3 or D1/D5 dopaminergic receptors in normal human T-cells and triggers the selective secretion of either IL-10, TNFalpha or both.

21 January 2018

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The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes

21 January 2018

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The CD8 T-cell road to immunotherapy of toxoplasmosis

21 January 2018

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Psychiatric disorders in toxoplasma seropositive patients--the CD8 connection

21 January 2018

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Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

D3 dopamine receptor mRNA is elevated in T cells of schizophrenic patients whereas D4 dopamine receptor mRNA is reduced in CD4+ -T cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Increase in dopaminergic, but not serotoninergic, receptors in T-cells as a marker for schizophrenia severity.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Adaptive immunity affects learning behavior in mice.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Increased levels of CD8+ and CD4+ 45RA+ lymphocytes in schizophrenic patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Antipsychotic drugs suppress the AKT/NF-κB pathway and regulate the differentiation of T-cell subsets.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Altered T-cell function in schizophrenia: a cellular model to investigate molecular disease mechanisms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Neuroprogression in schizophrenia: Pathways underpinning clinical staging and therapeutic corollaries

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: associations and functional implications

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Th17 pathway-mediated immunopathogenesis of schizophrenia: mechanisms and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Fetal programming of schizophrenia: select mechanisms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Innate immune response is differentially dysregulated between bipolar disease and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Activation of Th17 cells in drug naïve, first episode schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Neuroinflammation in schizophrenia-related psychosis: a PET study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

An activated set point of T-cell and monocyte inflammatory networks in recent-onset schizophrenia patients involves both pro- and anti-inflammatory forces.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Molecular mechanisms involved in T cell migration across the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Type II collagen induces peripheral tolerance in BALB/c mice via the generation of CD8+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

In vitro-induced cell-mediated immune deviation to encephalitogenic antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The in vivo and in vitro induction of anterior chamber associated immune deviation to myelin antigens in C57BL/6 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The emergence of neurotransmitters as immune modulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The role of genetic variations of immune system regulatory molecules CD28 and CTLA-4 in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Gene expression analysis reveals schizophrenia-associated dysregulation of immune pathways in peripheral blood mononuclear cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Neuroprotective immunity: T cell-derived glutamate endows astrocytes with a neuroprotective phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

γδ T cells as early sensors of tissue damage and mediators of secondary neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Neuroprotective activities of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Dopamine inhibits cytokine release and expression of tyrosine kinases, Lck and Fyn in activated T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Dopamine fails to regulate activation of peripheral blood lymphocytes from multiple sclerosis patients: effects of IFN-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Abnormalities in metabolism and hypothalamic-pituitary-adrenal axis function in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Phenotypic heterogeneity of antigen-specific CD4 T cells under different conditions of antigen persistence and antigen load

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Functional heterogeneity of memory CD4 T cell responses in different conditions of antigen exposure and persistence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Prenatal and postnatal animal models of immune activation: relevance to a range of neurodevelopmental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The role of T helper cells in neuroprotection and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Differential effects on T-cell function following exposure to serum from schizophrenia smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Identification of a molecular profile associated with immune status in first-onset schizophrenia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Immune system disturbances in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The dopamine hypothesis of schizophrenia: version III--the final common pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

A peripheral marker for schizophrenia: Increased levels of D3 dopamine receptor mRNA in blood lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Cigarette smoking and mortality risk in people with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Inflammation and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Change of dopamine receptor mRNA expression in lymphocyte of schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Dopamine interacts directly with its D3 and D2 receptors on normal human T cells, and activates beta1 integrin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Dopamine and T cells: dopamine receptors and potent effects on T cells, dopamine production in T cells, and abnormalities in the dopaminergic system in T cells in autoimmune, neurological and psychiatric diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

CTLA-4 confers a risk of recurrent schizophrenia, major depressive disorder and bipolar disorder in the Chinese Han population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Identification of the mRNA expression status of the dopamine D2 receptor and dopamine transporter in peripheral blood lymphocytes of schizophrenia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Methylation patterns in whole blood correlate with symptoms in schizophrenia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Maternal Lipopolysaccharide Exposure Promotes Immunological Functional Changes in Adult Offspring CD4+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Microglial activation and chronic neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Preferential development of Th17 cells in offspring of immunostimulated pregnant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Maternal immune stimulation during pregnancy shapes the immunological phenotype of offspring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Lymphocyte subsets in schizophrenic disorders. Relationship with clinical, neuromorphological and treatment variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Flow cytometric analysis of T cell subsets in paired samples of cerebrospinal fluid and peripheral blood from patients with neurological and psychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Developmental neuroinflammation and schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Meta-analysis of lymphocytes in schizophrenia: clinical status and antipsychotic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Cytokines and schizophrenia: Microglia hypothesis of schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Neuroinflammation in schizophrenia especially focused on the role of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Increased frequency of CD8 positive gamma/delta T-lymphocytes (CD8+ gamma/delta+) in unmedicated schizophrenic patients: relation to impairment of the blood-brain barrier and HLA-DPA*02011.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Schizophrenia as an inflammation-mediated dysbalance of glutamatergic neurotransmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Immune System and Schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Neuroinflammation and psychiatric illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Neuroinflammation and white matter pathology in schizophrenia: systematic review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Role of dopamine in the physiology of T-cells and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The dopaminergic system in autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Antipsychotic treatment may alter T-helper (TH) 2 arm cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Excessive extracellular volume reveals a neurodegenerative pattern in schizophrenia onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Immune involvement in schizophrenia and autism: etiology, pathology and animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Possible mechanisms of neurodegeneration in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Stimulation of dopamine receptor D5 expressed on dendritic cells potentiates Th17-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Modulation of T-cell mediated immunity by dopamine receptor d5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Decreased T cellular immune response in schizophrenic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Biological insights from 108 schizophrenia-associated genetic loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Circulating dopamine level, in lung carcinoma patients, inhibits proliferation and cytotoxicity of CD4+ and CD8+ T cells by D1 dopamine receptors: an in vitro analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The immunoregulatory role of dopamine: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

A comprehensive macrophage-T-lymphocyte theory of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The macrophage-T-lymphocyte theory of schizophrenia: Additional evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Variations of nucleus accumbens dopamine and serotonin following systemic interleukin-1, interleukin-2 or interleukin-6 treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Acute schizophrenia is accompanied by reduced T cell and increased B cell immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Microglia activation in recent-onset schizophrenia: a quantitative (R)-[11C]PK11195 positron emission tomography study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The TRIPS (Toll-like receptors in immuno-inflammatory pathogenesis) Hypothesis: a novel postulate to understand schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Decreased levels of dopamine D3 receptor mRNA in schizophrenic and bipolar patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Dopamine selectively induces migration and homing of naive CD8+ T cells via dopamine receptor D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The Th17 pathway and inflammatory diseases of the intestines, lungs, and skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Toxoplasma and schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

The effects of Ginkgo biloba extract added to haloperidol on peripheral T cell subsets in drug-free schizophrenia: a double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Th17 cell-mediated neuroinflammation is involved in neurodegeneration of aβ1-42-induced Alzheimer's disease model rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Over-expression of dopamine D2 receptor and inwardly rectifying potassium channel genes in drug-naive schizophrenic peripheral blood lymphocytes as potential diagnostic markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Recent advances in psychoneuroimmunology: Inflammation in psychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11481-015-9626-9

Molecular neurobiology of dopaminergic receptors.

21 January 2018

1 reference

12 December 2020

Eye-mediated induction of specific immune tolerance to encephalitogenic antigens

1 reference

12 December 2020

T-lymphocyte entry into the central nervous system

1 reference

12 December 2020

Lymphocyte subpopulations in peripheral blood from schizophrenic patients

1 reference

12 December 2020

Effects of risperidone on cytokine profile in drug-naïve first-episode psychosis.

1 reference

12 December 2020

Abnormal distributions of T-lymphocyte subsets in the cerebrospinal fluid of patients with acute schizophrenia

1 reference

12 December 2020

T-cell subsets in schizophrenia: a comparison between drug-naive first episode patients and chronic schizophrenic patients

1 reference

12 December 2020

Clozapine inhibits Th1 cell differentiation and causes the suppression of IFN-γ production in peripheral blood mononuclear cells

1 reference

12 December 2020

Elevated Le(y) antigen expression on T-lymphocytes in schizophrenic patients

1 reference

12 December 2020

Lymphocytes in schizophrenic patients under therapy: serological, morphological and cell subset findings

1 reference

12 December 2020

Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study

1 reference

12 December 2020

Neuroprogression in schizophrenia: Pathways and underpinning clinical staging and therapeutic corollaries

1 reference

12 December 2020

Accumulation of macrophages in the CSF of schizophrenic patients during acute psychotic episodes

1 reference

12 December 2020

Is the dopamine D3 receptor mRNA on blood lymphocytes help to for identification and subtyping of schizophrenia?

1 reference

12 December 2020

Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

1 reference

12 December 2020

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

1 reference

12 December 2020

Interactions of innate and adaptive immunity in brain development and function.

1 reference

12 December 2020

Increase in expression of adhesion molecule receptors on T helper cells during antipsychotic treatment and relationship to blood-brain barrier permeability in schizophrenia.

1 reference

12 December 2020

Increased frequency of activated lymphocytes in the cerebrospinal fluid of patients with acute schizophrenia

1 reference

12 December 2020

An analysis of lymphocyte subpopulations in schizophrenic patients

1 reference

12 December 2020

T-lymphocyte subpopulations in schizophrenic patients

1 reference

12 December 2020

T lymphocytes in schizophrenia

1 reference

12 December 2020

Decreased T cell response to mitogen and increased anti-cytoplasmic antibody in drug-free schizophrenic patients

1 reference

12 December 2020

T-cell subsets in acute psychotic schizophrenic patients

1 reference

12 December 2020

Aberrant T cell-mediated immunity in untreated schizophrenic patients: deficient interleukin-2 production

1 reference

12 December 2020

T- and B-lymphocytes in patients with schizophrenia in acute psychotic episode and the course of the treatment

1 reference

12 December 2020

T-cells and psychopathology in schizophrenia: relationship to the outcome of neuroleptic therapy

1 reference

12 December 2020

Dopaminergic regulation of immune cells via D3 dopamine receptor: a pathway mediated by activated T cells

1 reference

12 December 2020

Cellular immunity in schizophrenic patients before and during neuroleptic treatment

1 reference

12 December 2020

10.1007/S11481-015-9626-9

Identifiers

DOI

1 reference

Dimensions Publication ID

4 September 2017

1018906908

0 references

1 reference