(Q38550900)

4 September 2017

1 reference

title

A mechanistic review of silica-induced inhalation toxicity (English)

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4 September 2017

Hajime Kawasaki

1

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4 September 2017

publication date

21 July 2015

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4 September 2017

published in

Inhalation Toxicology

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4 September 2017

volume

27

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4 September 2017

issue

8

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4 September 2017

page(s)

363-377

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Innate immunity and adjuvants

4 September 2017

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Silica and its antagonistic effects on transforming growth factor-beta in lung fibroblast extracellular matrix production

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Mediators of chronic obstructive pulmonary disease

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Silica suppresses Toll-like receptor ligand-induced dendritic cell activation

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Innate immune processes are sufficient for driving silicosis in mice.

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Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages

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G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent

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Macrophage deactivation by interleukin 10

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Transforming growth factor beta in tissue fibrosis

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Neutrophil granules: a library of innate immunity proteins

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Subchronic endotoxin inhalation causes persistent airway disease

21 January 2018

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RETRACTED: Innate immune activation by inhaled lipopolysaccharide, independent of oxidative stress, exacerbates silica-induced pulmonary fibrosis in mice

21 January 2018

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The Nalp3 inflammasome is essential for the development of silicosis

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Silicosis and coal workers' pneumoconiosis

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Effect of inhaled crystalline silica in a rat model: time course of pulmonary reactions

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Antifibrotic effect of interferon gamma in silicosis model of rat.

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Pneumoconiosis: comparison of imaging and pathologic findings.

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Activation of murine macrophages by silica particles in vitro is a process independent of silica-induced cell death

21 January 2018

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T cell contributions to the different phases of granuloma formation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Occupational exposures and autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Interleukin-12 is not essential for silicosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Role of interferon-gamma in the development of murine bronchus-associated lymphoid tissues induced by silica in vivo

21 January 2018

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Diseases caused by silica: mechanisms of injury and disease development

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Kinetics of the bronchoalveolar leucocyte response in rats during exposure to equal airborne mass concentrations of quartz, chrysotile asbestos, or titanium dioxide

21 January 2018

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Asbestos-stimulated tumour necrosis factor release from alveolar macrophages depends on fibre length and opsonization.

21 January 2018

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

21 January 2018

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Pulmonary response to silica or titanium dioxide: inflammatory cells, alveolar macrophage-derived cytokines, and histopathology

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

TNFalpha and MIP-2: role in particle-induced inflammation and regulation by oxidative stress

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Interleukin-6 as a key player in systemic inflammation and joint destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Redox signaling in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

House dust endotoxin and allergic sensitization in children

21 January 2018

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21 January 2018

Chemokines and disease

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Metropolitan home living conditions associated with indoor endotoxin levels

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Does vitreous silica contradict the toxicity of the crystalline silica paradigm?

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Type I Interferon Signaling Contributes to Chronic Inflammation in a Murine Model of Silicosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Alternative activation of macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Silica-induced apoptosis in murine macrophage: involvement of tumor necrosis factor-alpha and nuclear factor-kappaB activation.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The inflammasome: an integrated view

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

APC-derived cytokines and T cell polarization in autoimmune inflammation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Recognition and plasma clearance of endotoxin by scavenger receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Interleukin-6 and the acute phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Biological and clinical aspects of interleukin 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Determinants of house dust, endotoxin, and β-(1→3)-D-glucan in homes of Danish children.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Role of mitochondria in silica-induced apoptosis of alveolar macrophages: inhibition of apoptosis by rhodamine 6G and N-acetyl-L-cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Immunoglobulin responses to experimental silicosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Role of Interleukin-10 in the Lung Response to Silica in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Small molecule inhibitors of RORγt: targeting Th17 cells and other applications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Endotoxin levels in homes and classrooms of Dutch school children and respiratory health.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Grain dust and endotoxin inhalation challenges produce similar inflammatory responses in normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The bedding of laboratory animals as a source of airborne contaminants.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The WASH approach: fighting waterborne diseases in emergency situations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Nitric oxide up-regulates DNA-binding activity of nuclear factor-kB in macrophages stimulated with silica and inflammatory stimulants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The roles of TLRs, RLRs and NLRs in pathogen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Classification and natural history of the idiopathic interstitial pneumonias

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Transient expression of IL-1beta induces acute lung injury and chronic repair leading to pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Induction of interleukin-1 and interleukin-8 mRNAs and proteins by TGF beta 1 in rat lung alveolar epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Transforming growth factor-beta suppresses interferon-gamma-induced toxoplasmastatic activity in murine macrophages by inhibition of tumour necrosis factor-alpha production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Tobacco smoking increases dramatically air concentrations of endotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Pulmonary response of rats exposed to titanium dioxide (TiO2) by inhalation for two years.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The TNF and TNF receptor superfamilies: integrating mammalian biology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The chemokine system in diverse forms of macrophage activation and polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Health hazards due to the inhalation of amorphous silica

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Interferons and autoimmune disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Dose-response relationship to inhaled endotoxin in normal subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Epidemiology of environmental exposures and human autoimmune diseases: findings from a National Institute of Environmental Health Sciences Expert Panel Workshop

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Systemic macrophage stimulation in rats with silicosis: enhanced release of tumor necrosis factor-alpha from alveolar and peritoneal macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Enhanced release of prostaglandin E2 from macrophages of rats with silicosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

From granuloma to fibrosis in interstitial lung diseases: molecular and cellular interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Possible mechanisms to explain dust overloading of the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Exploring the full spectrum of macrophage activation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription

21 January 2018

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Crystalline and amorphous silica differentially regulate the cyclooxygenase-prostaglandin pathway in pulmonary fibroblasts: implications for pulmonary fibrosis

21 January 2018

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The biological functions of T helper 17 cell effector cytokines in inflammation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

p38 and Src-ERK1/2 pathways regulate crystalline silica-induced chemokine release in pulmonary epithelial cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Are cats and dogs the major source of endotoxin in homes?

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Predictors of airborne endotoxin in the home

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Macrophage class A scavenger receptor-mediated phagocytosis of Escherichia coli: role of cell heterogeneity, microbial strain, and culture conditions in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Time course of pulmonary response of rats to inhalation of crystalline silica: histological results and biochemical indices of damage, lipidosis, and fibrosis

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Time course of pulmonary response of rats to inhalation of crystalline silica: NF-kappa B activation, inflammation, cytokine production, and damage

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Progression of lung inflammation and damage in rats after cessation of silica inhalation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Nitric oxide and reactive oxygen species production causes progressive damage in rats after cessation of silica inhalation

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Reactive oxygen and nitrogen species in normal physiological processes

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The sources of inflammatory mediators in the lung after silica exposure

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Endotoxin-stimulated innate immunity: A contributing factor for asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Bronchus associated lymphoid tissue (BALT) in human lung: its distribution in smokers and non-smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Basic pathogenetic mechanisms in silicosis: current understanding

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Cells, mediators and Toll-like receptors in COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Multiple modes of responses to air pollution particulate materials in A549 alveolar type II cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Blood gene expression profiling detects silica exposure and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Reactive oxygen species and silica-induced carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Endocytosis, oxidative stress and IL-8 expression in human lung epithelial cells upon treatment with fine and ultrafine TiO2: role of the specific surface area and of surface methylation of the particles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Enzymes in lung lavage fluid after inhalation exposure to silica dust

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Tregs promote the differentiation of Th17 cells in silica-induced lung fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Diesel exhaust particles induced release of interleukin 6 and 8 by (primed) human bronchial epithelial cells (BEAS 2B) in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Lung epithelial cell (A549) interaction with unopsonized environmental particulates: quantitation of particle-specific binding and IL-8 production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Tumor necrosis factor-alpha induces transforming growth factor-beta1 expression in lung fibroblasts through the extracellular signal-regulated kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Specificity in reactive oxidant signaling: think globally, act locally

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Lung inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Differential binding of inorganic particles to MARCO

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Critical role of MARCO in crystalline silica-induced pulmonary inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Type I interferons (alpha/beta) in immunity and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

The inflammatory response in humans after inhalation of bacterial endotoxin: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Granulomatous inflammation--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Identification and characterization of macrophage inflammatory protein 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Biological effects of ultrafine model particles in human macrophages and epithelial cells in mono- and co-culture

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Role of residual additives in the cytotoxicity and cytokine release caused by polyvinyl chloride particles in pulmonary cell cultures.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Response of alveolar macrophages from inducible nitric oxide synthase knockout or wild-type mice to an in vitro lipopolysaccharide or silica exposure

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Pulmonary inflammation and fibrosis following subacute inhalational exposure to silica: determinants of progression

21 January 2018

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https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

Persistent Depletion of I Kappa B Alpha and Interleukin-8 Expression in Human Pulmonary Epithelial Cells Exposed to Quartz Particles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08958378.2015.1066905

10.3109/08958378.2015.1066905

21 January 2018

Identifiers

DOI

1 reference

4 September 2017

1 reference