(Q38599692)

4 September 2017

Pathology and immune reactivity: understanding multidimensionality in pulmonary tuberculosis (English)

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4 September 2017

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Anca Dorhoi

1

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PubMed ID

26438324

4 September 2017

Stefan H E Kaufmann

series ordinal

2

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4 September 2017

5 October 2015

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Seminars in Immunopathology

4 September 2017

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4 September 2017

38

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4 September 2017

2

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4 September 2017

153-166

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https://scigraph.springernature.com/pub.10.1007/s00281-015-0531-3

4 September 2017

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cites work

CXCR5⁺ T helper cells mediate protective immunity against tuberculosis

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12 December 2020

Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

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12 December 2020

Location of persisting mycobacteria in a Guinea pig model of tuberculosis revealed by r207910.

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12 December 2020

Radiological cavitation, sputum mycobacterial load and treatment response in pulmonary tuberculosis

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12 December 2020

The balance between protective and pathogenic immune responses in the TB-infected lung

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12 December 2020

Interception of host angiogenic signalling limits mycobacterial growth.

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12 December 2020

Animal models of tuberculosis: Guinea pigs

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12 December 2020

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis

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12 December 2020

Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

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12 December 2020

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis.

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12 December 2020

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis.

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12 December 2020

Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice

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12 December 2020

Is tuberculosis a lymphatic disease with a pulmonary portal?

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12 December 2020

Langhans giant cells from M. tuberculosis-induced human granulomas cannot mediate mycobacterial uptake.

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12 December 2020

Mycobacteria target DC-SIGN to suppress dendritic cell function

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12 December 2020

Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases

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12 December 2020

Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis

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12 December 2020

Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas

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12 December 2020

Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium tuberculosis infection

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12 December 2020

Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.

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12 December 2020

Suppressive functions of B cells in infectious diseases

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12 December 2020

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis

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12 December 2020

Increased serum level of vascular endothelial growth factor in pulmonary tuberculosis

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12 December 2020

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

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12 December 2020

CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis

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12 December 2020

Immunopathologic effects of tumor necrosis factor alpha in murine mycobacterial infection are dose dependent

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12 December 2020

The role of the granuloma in expansion and dissemination of early tuberculous infection

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12 December 2020

M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells

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12 December 2020

Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo.

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12 December 2020

Multiscale computational modeling reveals a critical role for TNF-α receptor 1 dynamics in tuberculosis granuloma formation

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12 December 2020

Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines.

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12 December 2020

MMP-1 drives immunopathology in human tuberculosis and transgenic mice.

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12 December 2020

Over-expression of thymosin β4 in granulomatous lung tissue with active pulmonary tuberculosis.

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12 December 2020

Mycobacterium tuberculosis dysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation

1 reference

12 December 2020

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity

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12 December 2020

The Extracellular Matrix Regulates Granuloma Necrosis in Tuberculosis.

1 reference

12 December 2020

Mycobacterium tuberculosis infection of the 'non-classical immune cell'.

1 reference

12 December 2020

Cutting edge: control of Mycobacterium tuberculosis infection by a subset of lung parenchyma-homing CD4 T cells

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12 December 2020

Inoculation dose of Mycobacterium tuberculosis does not influence priming of T cell responses in lymph nodes

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12 December 2020

Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis -induced inflammation and virulence

1 reference

12 December 2020

Neutrophils exacerbate tuberculosis infection in genetically susceptible mice.

1 reference

12 December 2020

Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection

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12 December 2020

Infection of B cell-deficient mice with CDC 1551, a clinical isolate of Mycobacterium tuberculosis: delay in dissemination and development of lung pathology

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12 December 2020

DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells

1 reference

12 December 2020

A humanized mouse model of tuberculosis

1 reference

12 December 2020

NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis

1 reference

12 December 2020

Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti

1 reference

12 December 2020

ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis

1 reference

12 December 2020

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

1 reference

12 December 2020

Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits

1 reference

12 December 2020

Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

1 reference

12 December 2020

Roles of cytotoxic delayed-type hypersensitivity and macrophage-activating cell-mediated immunity in the pathogenesis of tuberculosis

1 reference

12 December 2020

Pathology of postprimary tuberculosis in humans and mice: contradiction of long-held beliefs

1 reference

12 December 2020

ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

1 reference

12 December 2020

Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections

1 reference

12 December 2020

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

1 reference

12 December 2020

Mycobacterium tuberculosis activates the DNA-dependent cytosolic surveillance pathway within macrophages

1 reference

12 December 2020

The relation between CT findings and sputum microbiology studies in active pulmonary tuberculosis.

1 reference

12 December 2020

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

1 reference

12 December 2020

Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium

1 reference

12 December 2020

Tuberculosis, pulmonary cavitation, and matrix metalloproteinases.

1 reference

12 December 2020

A new unifying theory of the pathogenesis of tuberculosis

1 reference

12 December 2020

Antibody-independent functions of B cells: a focus on cytokines

1 reference

12 December 2020

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome-dependent processing of IL-1β.

1 reference

12 December 2020

Liquefaction and cavity formation in pulmonary TB: a simple method in rabbit skin to test inhibitors

1 reference

12 December 2020

Mycobacterial glycolipid trehalose 6,6'-dimycolate-induced hypersensitive granulomas: contribution of CD4+ lymphocytes

1 reference

12 December 2020

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

1 reference

12 December 2020

Human lung hydrolases delineate Mycobacterium tuberculosis-macrophage interactions and the capacity to control infection

1 reference

12 December 2020

Impaired antigen-specific CD4(+) T lymphocyte responses in cavitary tuberculosis

1 reference

12 December 2020

Radiologic Responses in Cynomolgus Macaques for Assessing Tuberculosis Chemotherapy Regimens

1 reference

12 December 2020

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

1 reference

12 December 2020

B cells moderate inflammatory progression and enhance bacterial containment upon pulmonary challenge with Mycobacterium tuberculosis

1 reference

12 December 2020

Additional drug resistance in Mycobacterium tuberculosis isolates from resected cavities among patients with multidrug-resistant or extensively drug-resistant pulmonary tuberculosis

1 reference

12 December 2020

Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection

1 reference

12 December 2020

Early events in Mycobacterium tuberculosis infection in cynomolgus macaques

1 reference

12 December 2020

Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms

1 reference

12 December 2020

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

1 reference

12 December 2020

Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule

1 reference

12 December 2020

Pathology of post primary tuberculosis of the lung: an illustrated critical review

1 reference

12 December 2020

Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice

1 reference

12 December 2020

The beta-glucan receptor dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria

1 reference

12 December 2020

The role of the innate immune system in granulomatous disorders

1 reference

12 December 2020

Strains of Mycobacterium tuberculosis from western Maharashtra, India, exhibit a high degree of diversity and strain-specific associations with drug resistance, cavitary disease, and treatment failure

1 reference

12 December 2020

Tumor necrosis factor neutralization results in disseminated disease in acute and latent Mycobacterium tuberculosis infection with normal granuloma structure in a cynomolgus macaque model

1 reference

12 December 2020

Immunopathology of postprimary tuberculosis: increased T-regulatory cells and DEC-205-positive foamy macrophages in cavitary lesions

1 reference

12 December 2020

Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rbeta1 isoform that enhances DC migration

1 reference

12 December 2020

Robert Koch, the Nobel Prize, and the ongoing threat of tuberculosis

1 reference

12 December 2020

Extrapulmonary dissemination of Mycobacterium bovis but not Mycobacterium tuberculosis in a bronchoscopic rabbit model of cavitary tuberculosis

1 reference

12 December 2020

Neutrophil-mediated innate immune resistance to mycobacteria

1 reference

12 December 2020

Cell-to-cell transfer of M. tuberculosis antigens optimizes CD4 T cell priming

1 reference

12 December 2020

Evolution of foamy macrophages in the pulmonary granulomas of experimental tuberculosis models

1 reference

12 December 2020

Host evasion and exploitation schemes of Mycobacterium tuberculosis

1 reference

12 December 2020

AhR sensing of bacterial pigments regulates antibacterial defence.

1 reference

12 December 2020

The behavior of pulmonary tuberculous lesions; a pathological study

1 reference

12 December 2020

Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence

1 reference

12 December 2020

Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo.

1 reference

12 December 2020

Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response

1 reference

12 December 2020

Baseline predictors of sputum culture conversion in pulmonary tuberculosis: importance of cavities, smoking, time to detection and W-Beijing genotype

1 reference

12 December 2020

Local immune responses correlate with presentation and outcome in tuberculosis

1 reference

12 December 2020

Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4 T cells

1 reference

12 December 2020

Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients

1 reference

12 December 2020

Exogenous reinfection in tuberculosis

1 reference

12 December 2020

Clinical and radiographic correlates of primary and reactivation tuberculosis: a molecular epidemiology study

1 reference

12 December 2020

Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent

1 reference

12 December 2020

The time-table of tuberculosis

1 reference

12 December 2020

Novel regimens identified in mice for treatment of latent tuberculosis infection in contacts of patients with multidrug-resistant tuberculosis

1 reference

12 December 2020

S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis

1 reference

12 December 2020

A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis.

1 reference

12 December 2020

Expression of many immunologically important genes in Mycobacterium tuberculosis-infected macrophages is independent of both TLR2 and TLR4 but dependent on IFN-alphabeta receptor and STAT1.

1 reference

12 December 2020

Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci

1 reference

12 December 2020

Granuloma formation and host defense in chronic Mycobacterium tuberculosis infection requires PYCARD/ASC but not NLRP3 or caspase-1.

1 reference

12 December 2020

The formation of the granuloma in tuberculosis infection

1 reference

12 December 2020

Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

1 reference

12 December 2020

Arginase-1 expression in granulomas of tuberculosis patients.

1 reference

12 December 2020

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

1 reference

12 December 2020

The key role of exudative lesions and their encapsulation: lessons learned from the pathology of human pulmonary tuberculosis

1 reference

12 December 2020

Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection

1 reference

12 December 2020

Cell wall lipids from Mycobacterium bovis BCG are inflammatory when inoculated within a gel matrix: characterization of a new model of the granulomatous response to mycobacterial components.

1 reference

12 December 2020

Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis.

1 reference

12 December 2020

Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas

1 reference

12 December 2020

Lung-residing myeloid-derived suppressors display dual functionality in murine pulmonary tuberculosis

1 reference

12 December 2020

Adventures within the speckled band: heterogeneity, angiogenesis, and balanced inflammation in the tuberculous granuloma.

1 reference

12 December 2020

The immune response in tuberculosis

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12 December 2020

iNKT cell production of GM-CSF controls Mycobacterium tuberculosis.

1 reference

12 December 2020

Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis

1 reference

12 December 2020

Induced sputum MMP-1, -3 & -8 concentrations during treatment of tuberculosis

1 reference

12 December 2020

Lung remodeling in pulmonary tuberculosis

1 reference

12 December 2020

γδ T cells cross-link innate and adaptive immunity in Mycobacterium tuberculosis infection.

1 reference

12 December 2020

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

1 reference

12 December 2020

A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis

1 reference

12 December 2020

Contact investigation for tuberculosis: a systematic review and meta-analysis.

1 reference

12 December 2020

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

1 reference

12 December 2020

Differences in mannose receptor-mediated uptake of lipoarabinomannan from virulent and attenuated strains of Mycobacterium tuberculosis by human macrophages

1 reference

12 December 2020

Mycobacterium tuberculosis: success through dormancy

1 reference

12 December 2020

Macrophage phagocytosis of virulent but not attenuated strains of Mycobacterium tuberculosis is mediated by mannose receptors in addition to complement receptors

1 reference

12 December 2020

NALP3 is not necessary for early protection against experimental tuberculosis.

1 reference

12 December 2020

Platelets direct monocyte differentiation into epithelioid-like multinucleated giant foam cells with suppressive capacity upon mycobacterial stimulation

1 reference

12 December 2020

Noninvasive pulmonary [18F]-2-fluoro-deoxy-D-glucose positron emission tomography correlates with bactericidal activity of tuberculosis drug treatment

1 reference

12 December 2020

Exogenous reinfection and pulmonary tuberculosis a study of the pathology

1 reference

12 December 2020

Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

1 reference

12 December 2020

Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection

1 reference

12 December 2020

Profiling early lung immune responses in the mouse model of tuberculosis

1 reference

12 December 2020

Rifapentine and isoniazid once a week versus rifampicin and isoniazid twice a week for treatment of drug-susceptible pulmonary tuberculosis in HIV-negative patients: a randomised clinical trial

1 reference

12 December 2020

The cellular immune response to Mycobacterium tuberculosis infection in the guinea pig.

1 reference

12 December 2020

Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization

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12 December 2020

Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses

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12 December 2020

Dissemination of Mycobacterium tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity.

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12 December 2020

Human tuberculous granulomas induce peripheral lymphoid follicle-like structures to orchestrate local host defence in the lung.

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12 December 2020

Versatile myeloid cell subsets contribute to tuberculosis-associated inflammation

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12 December 2020

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

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12 December 2020

Trehalose 6,6'-dimycolate (cord factor) of Mycobacterium tuberculosis induces foreign-body- and hypersensitivity-type granulomas in mice

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12 December 2020

Increased frequency of myeloid-derived suppressor cells during active tuberculosis and after recent mycobacterium tuberculosis infection suppresses T-cell function

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12 December 2020

Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas.

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12 December 2020

Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

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12 December 2020

Mathematical modeling of tuberculosis bacillary counts and cellular populations in the organs of infected mice.

1 reference

12 December 2020

Response of cultured macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes

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12 December 2020

Dectin-2 is a direct receptor for mannose-capped lipoarabinomannan of mycobacteria

1 reference

12 December 2020

Procollagen III N-terminal propeptide and desmosine are released by matrix destruction in pulmonary tuberculosis

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12 December 2020

Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection

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12 December 2020

Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death

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12 December 2020

Differential organization of the local immune response in patients with active cavitary tuberculosis or with nonprogressive tuberculoma.

1 reference

12 December 2020

Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity

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12 December 2020

Double-phase 18F-FDG PET-CT for determination of pulmonary tuberculoma activity

1 reference

12 December 2020

Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery

1 reference

12 December 2020

Allele-specific induction of IL-1β expression by C/EBPβ and PU.1 contributes to increased tuberculosis susceptibility

1 reference

12 December 2020

MicroRNA-223 controls susceptibility to tuberculosis by regulating lung neutrophil recruitment

1 reference

12 December 2020

A matrix metalloproteinase inhibitor promotes granuloma formation during the early phase of Mycobacterium tuberculosis pulmonary infection

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12 December 2020

Local immune responses in human tuberculosis: learning from the site of infection

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12 December 2020

Macrophages play a dual role during pulmonary tuberculosis in mice

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12 December 2020

Characterization of the tuberculous granuloma in murine and human lungs: cellular composition and relative tissue oxygen tension

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12 December 2020

Bacillary replication and macrophage necrosis are determinants of neutrophil recruitment in tuberculosis

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12 December 2020

Tuberculosis and granuloma formation in patients receiving anti-TNF therapy

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12 December 2020

Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas

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12 December 2020

Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes

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12 December 2020

Trehalose 6,6'-dimycolate and lipid in the pathogenesis of caseating granulomas of tuberculosis in mice.

1 reference

12 December 2020

Neutrophil granules in health and disease

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12 December 2020

Mycobacterium tuberculosis keto-mycolic acid and macrophage nuclear receptor TR4 modulate foamy biogenesis in granulomas: a case of a heterologous and noncanonical ligand-receptor pair

1 reference

12 December 2020

Essential yet limited role for CCR2⁺ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming

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12 December 2020

Mycobacterium tuberculosis up-regulates matrix metalloproteinase-1 secretion from human airway epithelial cells via a p38 MAPK switch

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12 December 2020

Cell-autonomous effector mechanisms against mycobacterium tuberculosis

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12 December 2020

Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo

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12 December 2020

Mycobacterial lipomannan induces granuloma macrophage fusion via a TLR2-dependent, ADAM9- and beta1 integrin-mediated pathway

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12 December 2020

Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice

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12 December 2020

Cattle as a model for development of vaccines against human tuberculosis.

1 reference

12 December 2020

10.1007/S00281-015-0531-3

Identifiers

DOI

1 reference

PubMed ID

26438324

Dimensions Publication ID

4 September 2017

0 references

1 reference

PubMed ID

26438324