(Q38613789)

4 September 2017

title

Ineffective erythropoiesis and regulation of iron status in iron loading anaemias (English)

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ineffective erythropoiesis

4 September 2017

main subject

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26491866%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Clara Camaschella

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26491866%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

English

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publication date

22 October 2015

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British Journal of Haematology

4 September 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26491866%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

172

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26491866%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26491866%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

512-523

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26491866%20AND%20SRC:MED&resulttype=core&format=json

Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1.

5 June 2020

cites work

1 reference

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

21 January 2018

1 reference

Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel

21 January 2018

1 reference

Congenital dyserythropoietic anemia type II (CDAII) is caused by mutations in the SEC23B gene.

21 January 2018

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The role of Smad signaling in hematopoiesis and translational hematology

21 January 2018

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Hepatocellular carcinoma in thalassaemia: an update of the Italian Registry.

21 January 2018

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Modulators of erythropoiesis: emerging therapies for hemoglobinopathies and disorders of red cell production.

21 January 2018

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Iron control of erythroid development by a novel aconitase-associated regulatory pathway

21 January 2018

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Understanding iron homeostasis through genetic analysis of hemochromatosis and related disorders

21 January 2018

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Hereditary sideroblastic anemias: pathophysiology, diagnosis, and treatment

21 January 2018

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21 January 2018

Treating iron overload.

1 reference

An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin

21 January 2018

1 reference

The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice.

21 January 2018

1 reference

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

21 January 2018

1 reference

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.

21 January 2018

1 reference

Concise review: growth differentiation factor 15 in pathology: a clinical role?

21 January 2018

1 reference

Recent advances in the understanding of iron overload in sideroblastic myelodysplastic syndrome

21 January 2018

1 reference

The serine protease TMPRSS6 is required to sense iron deficiency

21 January 2018

1 reference

An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia

21 January 2018

1 reference

Increased iron loading induces Bmp6 expression in the non-parenchymal cells of the liver independent of the BMP-signaling pathway

21 January 2018

1 reference

Activin receptor antagonists for cancer-related anemia and bone disease

21 January 2018

1 reference

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

21 January 2018

1 reference

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

21 January 2018

1 reference

Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes.

21 January 2018

1 reference

Hematologic responses to deferasirox therapy in transfusion-dependent patients with myelodysplastic syndromes

21 January 2018

1 reference

Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.

21 January 2018

1 reference

β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

21 January 2018

1 reference

Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia

21 January 2018

1 reference

Altered erythropoiesis and iron metabolism in carriers of thalassemia

21 January 2018

1 reference

Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice

21 January 2018

1 reference

JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis

21 January 2018

1 reference

Two to tango: regulation of Mammalian iron metabolism

21 January 2018

1 reference

Natural history of congenital dyserythropoietic anemia type II.

21 January 2018

1 reference

Congenital dyserythropoietic anemias: molecular insights and diagnostic approach

21 January 2018

1 reference

Hepcidin is suppressed by erythropoiesis in hemoglobin E β-thalassemia and β-thalassemia trait.

21 January 2018

1 reference

Molecular liaisons between erythropoiesis and iron metabolism

21 January 2018

1 reference

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

21 January 2018

1 reference

Identification of erythroferrone as an erythroid regulator of iron metabolism

21 January 2018

1 reference

Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia

21 January 2018

1 reference

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

21 January 2018

1 reference

Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function.

21 January 2018

1 reference

Transferrin receptor is necessary for development of erythrocytes and the nervous system

21 January 2018

1 reference

Transferrin therapy ameliorates disease in beta-thalassemic mice.

21 January 2018

1 reference

Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia

21 January 2018

1 reference

Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4.

21 January 2018

1 reference

SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts

21 January 2018

1 reference

HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.

21 January 2018

1 reference

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

21 January 2018

1 reference

Fetal hemoglobin levels and morbidity in untransfused patients with β-thalassemia intermedia.

21 January 2018

1 reference

Serum ferritin level and morbidity risk in transfusion-independent patients with β-thalassemia intermedia: the ORIENT study

21 January 2018

1 reference

Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.

21 January 2018

1 reference

The second transferrin receptor regulates red blood cell production in mice

21 January 2018

1 reference

Hepcidin and β-thalassemia major.

21 January 2018

1 reference

Liver iron concentrations and urinary hepcidin in beta-thalassemia

21 January 2018

1 reference

Suppression of hepcidin during anemia requires erythropoietic activity

21 January 2018

1 reference

Hepcidin in iron overload disorders

21 January 2018

1 reference

Transfusion suppresses erythropoiesis and increases hepcidin in adult patients with β-thalassemia major: a longitudinal study

21 January 2018

1 reference

Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload

21 January 2018

1 reference

Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts

21 January 2018

1 reference

Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis

21 January 2018

1 reference

Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?

21 January 2018

1 reference

Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response

21 January 2018

1 reference

β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies

21 January 2018

1 reference

Hepcidin levels and their determinants in different types of myelodysplastic syndromes

21 January 2018

1 reference

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia

21 January 2018

1 reference

Combination therapy with a Tmprss6 RNAi-therapeutic and the oral iron chelator deferiprone additively diminishes secondary iron overload in a mouse model of β-thalassemia intermedia.

21 January 2018

1 reference

Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.

21 January 2018

1 reference

Myonectin (CTRP15), a novel myokine that links skeletal muscle to systemic lipid homeostasis

21 January 2018

1 reference

Skeletal muscle-derived myonectin activates the mammalian target of rapamycin (mTOR) pathway to suppress autophagy in liver

21 January 2018

1 reference

Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency

21 January 2018

1 reference

High levels of soluble serum hemojuvelin in patients with congenital dyserythropoietic anemia type I.

21 January 2018

1 reference

Impact of iron overload and potential benefit from iron chelation in low-risk myelodysplastic syndrome

21 January 2018

1 reference

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

21 January 2018

1 reference

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB.

21 January 2018

1 reference

Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis

21 January 2018

1 reference

Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia

21 January 2018

1 reference

Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: the OPTIMAL CARE study.

21 January 2018

1 reference

Optimal management of β thalassaemia intermedia.

21 January 2018

1 reference

Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I.

21 January 2018

1 reference

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

21 January 2018

1 reference

The definition and epidemiology of non-transfusion-dependent thalassemia

21 January 2018

1 reference

Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway

21 January 2018

1 reference

Low intracellular iron increases the stability of matriptase-2.

21 January 2018

1 reference

Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.

21 January 2018

1 reference

Serum hepcidin measured with an improved ELISA correlates with parameters of iron metabolism in patients with myelodysplastic syndrome

21 January 2018

1 reference

How I treat transfusional iron overload

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/BJH.13820

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26491866%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference