(Q38615385)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497526%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

The multiple facets of FcRn in immunity (English)

1 reference

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28 February 2020

4

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28 February 2020

author name string

Nigel M Stapleton

series ordinal

1

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28 February 2020

Helga K Einarsdóttir

series ordinal

2

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28 February 2020

Annette M Stemerding

series ordinal

3

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28 February 2020

publication date

1 November 2015

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28 February 2020

published in

Immunological Reviews

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28 February 2020

volume

268

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28 February 2020

issue

1

1 reference

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28 February 2020

page(s)

253-268

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497526%20AND%20SRC:MED&resulttype=core&format=json

Antibody production by single cells

28 February 2020

cites work

1 reference

Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

21 January 2018

1 reference

Receptors for aggregated IgG on mouse lymphocytes: their presence on thymocytes, thymus-derived, and bone marrow-derived lymphocytes

21 January 2018

1 reference

Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils

21 January 2018

1 reference

Purificaton of a functional mouse Fc receptor through the use of a monoclonal antibody

21 January 2018

1 reference

A complementary DNA clone for a macrophage-lymphocyte Fc receptor

21 January 2018

1 reference

The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones

21 January 2018

1 reference

FcgammaRIV: a novel FcR with distinct IgG subclass specificity

21 January 2018

1 reference

Phagocytosis of microbes: complexity in action

21 January 2018

1 reference

The transmission of immunity from mother to young and the catabolism of immunoglobulins

21 January 2018

1 reference

The protection receptor for IgG catabolism is the beta2-microglobulin-containing neonatal intestinal transport receptor

21 January 2018

1 reference

An IgG-transporting Fc receptor expressed in the syncytiotrophoblast of human placenta

21 January 2018

1 reference

An Fc receptor structurally related to MHC class I antigens

21 January 2018

1 reference

The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan

21 January 2018

1 reference

Perspective-- FcRn transports albumin: relevance to immunology and medicine

21 January 2018

1 reference

Receptor-mediated immunoglobulin G transport across mucosal barriers in adult life: functional expression of FcRn in the mammalian lung

21 January 2018

1 reference

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria

21 January 2018

1 reference

21 January 2018

1 reference

A variable number of tandem repeats polymorphism influences the transcriptional activity of the neonatal Fc receptor alpha-chain promoter.

21 January 2018

1 reference

The Role of FcRn in Antigen Presentation

21 January 2018

1 reference

Dependence of antibody-mediated presentation of antigen on FcRn

21 January 2018

1 reference

N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.

21 January 2018

1 reference

Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line

21 January 2018

1 reference

Crystal structure and immunoglobulin G binding properties of the human major histocompatibility complex-related Fc receptor(,)

21 January 2018

1 reference

Albumin binding to FcRn: distinct from the FcRn-IgG interaction.

21 January 2018

1 reference

The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin.

21 January 2018

1 reference

Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies

21 January 2018

1 reference

A passionate kiss, then run: exocytosis and recycling of IgG by FcRn.

21 January 2018

1 reference

Expression and crystallization of a soluble and functional form of an Fc receptor related to class I histocompatibility molecules

21 January 2018

1 reference

Crystal structure of the complex of rat neonatal Fc receptor with Fc

21 January 2018

1 reference

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

21 January 2018

1 reference

The heavy chain of neonatal Fc receptor for IgG is sequestered in endoplasmic reticulum by forming oligomers in the absence of beta2-microglobulin association

21 January 2018

1 reference

Membrane-anchored human FcRn can oligomerize in the absence of IgG.

21 January 2018

1 reference

Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential

21 January 2018

1 reference

Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

21 January 2018

1 reference

An intracellular traffic jam: Fc receptor-mediated transport of immunoglobulin G

21 January 2018

1 reference

FcRn-mediated antibody transport across epithelial cells revealed by electron tomography

21 January 2018

1 reference

Bidirectional transepithelial IgG transport by a strongly polarized basolateral membrane Fcgamma-receptor.

21 January 2018

1 reference

Tryptophan- and dileucine-based endocytosis signals in the neonatal Fc receptor

21 January 2018

1 reference

A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus

21 January 2018

1 reference

The MHC class I related Fc receptor, FcRn, is expressed in the epithelial cells of the human mammary gland.

21 January 2018

1 reference

Human neonatal Fc receptor mediates transport of IgG into luminal secretions for delivery of antigens to mucosal dendritic cells.

21 January 2018

1 reference

Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor

21 January 2018

1 reference

Nanogold as a specific marker for electron cryotomography

21 January 2018

1 reference

Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor

21 January 2018

1 reference

Structural Insights into Neonatal Fc Receptor-based Recycling Mechanisms

21 January 2018

1 reference

Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung

21 January 2018

1 reference

Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

21 January 2018

1 reference

Reduced elimination of IgG antibodies by engineering the variable region.

21 January 2018

1 reference

Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge

21 January 2018

1 reference

pH-dependent binding engineering reveals an FcRn affinity threshold that governs IgG recycling

21 January 2018

1 reference

Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2-microglobulin gene

21 January 2018

1 reference

Efficiency of immunoglobulin G replacement therapy in common variable immunodeficiency: correlations with clinical phenotype and polymorphism of the neonatal Fc receptor

21 January 2018

1 reference

Influence of FCGRT gene polymorphisms on pharmacokinetics of therapeutic antibodies

21 January 2018

1 reference

Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level

21 January 2018

1 reference

Recognition of the tryptophan-based endocytosis signal in the neonatal Fc Receptor by the mu subunit of adaptor protein-2.

21 January 2018

1 reference

Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

1 reference

Expression of the Fc receptor in the mammary gland during lactation in the marsupial Trichosurus vulpecula (brushtail possum).

21 January 2018

1 reference

Nonvectorial surface transport, endocytosis via a Di-leucine-based motif, and bidirectional transcytosis of chimera encoding the cytosolic tail of rat FcRn expressed in Madin-Darby canine kidney cells

21 January 2018

1 reference

A region from the medium chain adaptor subunit (mu) recognizes leucine- and tyrosine-based sorting signals

21 January 2018

1 reference

Medium chains of adaptor complexes AP-1 and AP-2 recognize leucine-based sorting signals from the invariant chain

21 January 2018

1 reference

A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis

21 January 2018

1 reference

The MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/lysosomal compartments

21 January 2018

1 reference

Linking cargo to vesicle formation: receptor tail interactions with coat proteins.

21 January 2018

1 reference

Ca2+-dependent calmodulin binding to FcRn affects immunoglobulin G transport in the transcytotic pathway

21 January 2018

1 reference

Comparison of the Fc glycosylation of fetal and maternal immunoglobulin G

21 January 2018

1 reference

Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells

21 January 2018

1 reference

H435-containing immunoglobulin G3 allotypes are transported efficiently across the human placenta: implications for alloantibody-mediated diseases of the newborn

21 January 2018

1 reference

Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions.

21 January 2018

1 reference

FcRn in the yolk sac endoderm of mouse is required for IgG transport to fetus

21 January 2018

1 reference

Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine

21 January 2018

1 reference

Antibodies and their receptors: different potential roles in mucosal defense.

21 January 2018

1 reference

Distribution of the IgG Fc receptor, FcRn, in the human fetal intestine

21 January 2018

1 reference

IgG is transported across the mouse yolk sac independently of FcgammaRIIb

21 January 2018

1 reference

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

21 January 2018

1 reference

FcRn: the neonatal Fc receptor comes of age.

21 January 2018

1 reference

There's been a Flaw in Our Thinking

21 January 2018

1 reference

Metabolic properties of IgG subclasses in man

21 January 2018

1 reference

On the perplexingly low rate of transport of IgG2 across the human placenta

21 January 2018

1 reference

Crystal structure at 2.2 A resolution of the MHC-related neonatal Fc receptor.

21 January 2018

1 reference

IgG subclasses and allotypes: from structure to effector functions

21 January 2018

1 reference

Human Gm, Km, and Am allotypes and their molecular characterization: a remarkable demonstration of polymorphism

21 January 2018

1 reference

Biological half-life of normal and truncated human IgG3 in scid mice

21 January 2018

1 reference

Specificity and affinity of human Fcgamma receptors and their polymorphic variants for human IgG subclasses.

21 January 2018

1 reference

An IgG3 switch variant of rituximab mediates enhanced complement-dependent cytotoxicity against tumour cells with low CD20 expression levels.

21 January 2018

1 reference

Crosstalk between human IgG isotypes and murine effector cells

21 January 2018

1 reference

Placental transport of immunoglobulin G.

21 January 2018

1 reference

The recycling and transcytotic pathways for IgG transport by FcRn are distinct and display an inherent polarity

21 January 2018

1 reference

Characterization of basolateral-targeting signals in the neonatal Fc receptor

21 January 2018

1 reference

Analysis of a family of antibodies with different half-lives in mice fails to find a correlation between affinity for FcRn and serum half-life

21 January 2018

1 reference

Human IgG2 antibodies display disulfide-mediated structural isoforms

21 January 2018

1 reference

Structural and functional characterization of disulfide isoforms of the human IgG2 subclass

21 January 2018

1 reference

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

21 January 2018

1 reference

Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia

21 January 2018

1 reference

A prominent lack of IgG1-Fc fucosylation of platelet alloantibodies in pregnancy

21 January 2018

1 reference

Divergent immunoglobulin g subclass activity through selective Fc receptor binding

21 January 2018

1 reference

Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport.

21 January 2018

1 reference

Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules.

21 January 2018

1 reference

Endocytosis of hepatitis B immune globulin into hepatocytes inhibits the secretion of hepatitis B virus surface antigen and virions

21 January 2018

1 reference

Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism

21 January 2018

1 reference

21 January 2018

1 reference

Functional Association between the Human Myeloid Immunoglobulin A Fc Receptor (CD89) and FcR [IMAGE] Chain

21 January 2018

1 reference

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

21 January 2018

1 reference

Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages

21 January 2018

1 reference

Activity of human IgG and IgA subclasses in immune defense against Neisseria meningitidis serogroup B.

21 January 2018

1 reference

Chimeric IgA antibodies against HLA class II effectively trigger lymphoma cell killing

21 January 2018

1 reference

21 January 2018

1 reference

Macrophages eliminate circulating tumor cells after monoclonal antibody therapy

21 January 2018

1 reference

Insights into immunoglobulin E receptor signaling from structurally defined ligands

21 January 2018

1 reference

Complement is activated by IgG hexamers assembled at the cell surface

21 January 2018

1 reference

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

21 January 2018

1 reference

How nascent phagosomes mature to become phagolysosomes

21 January 2018

1 reference

Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation.

21 January 2018

1 reference

Early degranulation of human neutrophils: Immunocytochemical studies of surface and intracellular phagocytic events

21 January 2018

1 reference

Localized exocytosis of primary (lysosomal) granules during phagocytosis: role of Ca2+-dependent tyrosine phosphorylation and microtubules

21 January 2018

1 reference

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells

21 January 2018

1 reference

AP-1 and ARF1 control endosomal dynamics at sites of FcR mediated phagocytosis

21 January 2018

1 reference

Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes

21 January 2018

1 reference

Clathrin/AP-2-dependent endocytosis: a novel playground for the pharmacological toolbox?

21 January 2018

1 reference

Tickets to ride: selecting cargo for clathrin-regulated internalization.

21 January 2018

1 reference

Dynamin 2 is required for phagocytosis in macrophages

21 January 2018

1 reference

Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis

21 January 2018

1 reference

ARF1.GTP, tyrosine-based signals, and phosphatidylinositol 4,5-bisphosphate constitute a minimal machinery to recruit the AP-1 clathrin adaptor to membranes

21 January 2018

1 reference

Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis

21 January 2018

1 reference

Natural killer cell signaling pathways

21 January 2018

1 reference

The neonatal FcR-mediated presentation of immune-complexed antigen is associated with endosomal and phagosomal pH and antigen stability in macrophages and dendritic cells.

21 January 2018

1 reference

FcRn overexpression in mice results in potent humoral response against weakly immunogenic antigen.

21 January 2018

1 reference

Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway.

21 January 2018

1 reference

A neonatal Fc receptor-targeted mucosal vaccine strategy effectively induces HIV-1 antigen-specific immunity to genital infection

21 January 2018

1 reference

Intranasal administration of antibody-bound respiratory syncytial virus particles efficiently primes virus-specific immune responses in mice

21 January 2018

1 reference

Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer.

21 January 2018

1 reference

Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand.

21 January 2018

1 reference

Model for the complex between protein G and an antibody Fc fragment in solution.

21 January 2018

1 reference

Characterization of the interaction between the herpes simplex virus type I Fc receptor and immunoglobulin G.

21 January 2018

1 reference

Fcγ Receptor-like Activity of Hepatitis C Virus Core Protein

21 January 2018

1 reference

Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens

21 January 2018

1 reference

A complex between the MHC class I homologue encoded by human cytomegalovirus and beta 2 microglobulin

21 January 2018

1 reference

Feedback regulation by IgG antibodies.

21 January 2018

1 reference

Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding

21 January 2018

1 reference

A Theoretical Model of γ-Globulin Catabolism

21 January 2018

1 reference

The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

21 January 2018

1 reference

1H NMR studies of the Fc region of human IgG1 and IgG3 immunoglobulins: Assignment of histidine resonances in the CH3 domain and identification of IgG3 protein carrying G3m(st) allotypes

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/IMR.12331

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26497526%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference