(Q38619216)

http://europepmc.org/abstract/PMC/5942222

15 June 2018

title

Mutations in the promoter of the telomerase gene TERT contribute to tumorigenesis by a two-step mechanism (English)

1 reference

http://europepmc.org/abstract/PMC/5942222

15 June 2018

author

Xavier Darzacq

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Boris C. Bastian

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Dirk Hockemeyer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Kunitoshi Chiba

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Franziska K Lorbeer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alan Shain

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

David Trombley McSwiggen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Areum Oh

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jekwan Ryu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Eva Schruf

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

17 August 2017

1 reference

http://europepmc.org/abstract/PMC/5942222

15 June 2018

published in

Science

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

6358

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

1416-1420

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

Whole-genome landscapes of major melanoma subtypes.

10 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Telomeres in cancer: tumour suppression and genome instability

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Endogenous Telomerase Reverse Transcriptase N-Terminal Tagging Affects Human Telomerase Function at Telomeres In Vivo

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

TERT Promoter Mutations Enhance Telomerase Activation by Long-Range Chromatin Interactions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

A POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plus

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

TERT promoter mutations in melanoma survival

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

The short and long telomere syndromes: paired paradigms for molecular medicine

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Cancer-associated TERT promoter mutations abrogate telomerase silencing

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Genomic Classification of Cutaneous Melanoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

The effect on melanoma risk of genes previously associated with telomere length

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Highly recurrent TERT promoter mutations in human melanoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

TERT promoter mutations in familial and sporadic melanoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Shorter telomeres associate with a reduced risk of melanoma development

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Genetic engineering of human pluripotent cells using TALE nucleases

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

A prospective study of telomere length and the risk of skin cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

The nature of telomere fusion and a definition of the critical telomere length in human cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

POT1 as a terminal transducer of TRF1 telomere length control

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Pot1, the putative telomere end-binding protein in fission yeast and humans

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Extension of life-span by introduction of telomerase into normal human cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Long telomeres and cancer risk among 95 568 individuals from the general population.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

The Genetic Evolution of Melanoma from Precursor Lesions

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Dynamic multiple-target tracing to probe spatiotemporal cartography of cell membranes.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Telomere dysfunction and the initiation of genome instability.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5942222

Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease

31 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28818973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28818973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28818973

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.AAO0535

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28818973%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

28818973

1 reference