(Q38687254)

5 September 2017

1 reference

title

Binding of plasminogen activators to fibrin: characterization and pharmacological consequences (English)

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5 September 2017

1 reference

Fears R

1

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PMC publication ID

1138828

5 September 2017

language of work or name

English

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publication date

1 July 1989

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5 September 2017

12

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inferred from page(s)

published in

Biochemical Journal

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5 September 2017

261

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5 September 2017

2

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5 September 2017

313-324

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Kinetics of the activation of plasminogen by human tissue plasminogen activator. Role of fibrin

5 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Secondary-site binding of Glu-plasmin, Lys-plasmin and miniplasmin to fibrin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Tissue-type plasminogen activator increases the binding of glu-plasminogen to clots

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

A randomised dose ranging study of recombinant tissue plasminogen activator in acute myocardial infarction.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Thrombolysis in Myocardial Infarction (TIMI) Trial--phase I: hemorrhagic manifestations and changes in plasma fibrinogen and the fibrinolytic system in patients treated with recombinant tissue plasminogen activator and streptokinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Binding of tissue plasminogen activator to cultured human endothelial cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Antibody-enhanced thrombolysis: targeting of tissue plasminogen activator in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Autonomous functions of structural domains on human tissue-type plasminogen activator

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Localization of the binding site of tissue-type plasminogen activator to fibrin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Involvement of finger domain and kringle 2 domain of tissue-type plasminogen activator in fibrin binding and stimulation of activity by fibrin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Complementary modes of action of tissue-type plasminogen activator and pro-urokinase by which their synergistic effect on clot lysis may be explained

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Interaction of one-chain and two-chain tissue plasminogen activator with intact and plasmin-degraded fibrin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Activation of plasminogen by pro-urokinase. I. Mechanism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Second-generation plasminogen activators

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Thrombolytic therapy: current status (1).

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Reperfusion therapy of acute myocardial infarction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Differences in the binding to fibrin of native plasminogen and plasminogen modified by proteolytic degradation influence of ω-aminocarboxylic acids

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

The mechanism of clot dissolution by plasmin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Structural Aspects of the Fibrinogen to Fibrin Conversion

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

On the biological significance of the specific interaction between fibrin, plasminogen and antiplasmin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Variants of human tissue-type plasminogen activator that lack specific structural domains of the heavy chain.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

The AH-site of plasminogen and two C-terminal fragments. A weak lysine-binding site preferring ligands not carrying a free carboxylate function

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Effects of human fibrinogen and its cleavage products on activation of human plasminogen by streptokinase.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Kinetic studies on the interaction of streptokinase and other plasminogen activators with plasminogen and fibrin

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Expression in E. coli of finger-domain lacking tissue-type plasminogen activator with high fibrin affinity

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Clinical effects and kinetic properties of intravenous APSAC--anisoylated plasminogen-streptokinase activator complex (BRL 26921) in acute myocardial infarction

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Conjugation to an antifibrin monoclonal antibody enhances the fibrinolytic potency of tissue plasminogen activator in vitro

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Structure-function analysis with tissue-type plasminogen activator. Effect of deletion of NH2-terminal domains on its biochemical and biological properties

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

The interaction of streptokinase.plasminogen activator complex, tissue-type plasminogen activator, urokinase and their acylated derivatives with fibrin and cyanogen bromide digest of fibrinogen. Relationship to fibrinolytic potency in vitro

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Variants of human tissue-type plasminogen activator. Fibrin binding, fibrinolytic, and fibrinogenolytic characterization of genetic variants lacking the fibronectin finger-like and/or the epidermal growth factor domains.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

A covalent molecular weight approximately 92,000 hybrid plasminogen activator derived from human plasmin fibrin-binding and tissue plasminogen activator catalytic domains

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

The effect of polymerised fibrin on the catalytic activities of one-chain tissue-type plasminogen activator as revealed by an analogue resistant to plasmin cleavage.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Thrombospondin-plasminogen interactions: modulation of plasmin generation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Characterization of a fusion protein consisting of amino acids 1 to 263 of tissue-type plasminogen activator and amino acids 144 to 411 of urokinase-type plasminogen activator.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Interaction of heparin with plasminogen activators and plasminogen: effects on the activation of plasminogen

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets: effects on surface proteins and platelet aggregation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Covalent molecular weight approximately 92 000 hybrid plasminogen activator derived from human plasmin amino-terminal and urokinase carboxyl-terminal domains

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Fibrin and plasminogen structures essential to stimulation of plasmin formation by tissue-type plasminogen activator.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Zymogen-activation kinetics. Modulatory effects of trans-4-(aminomethyl)cyclohexane-1-carboxylic acid and poly-D-lysine on plasminogen activation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Kinetic studies on the effect of heparin and fibrin on plasminogen activators

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Differences in the binding to fibrin of urokinase and tissue plasminogen activator

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138828

Morphology of bovine fibrinogen monomers and fibrin oligomers

31 August 2018

1 reference

12 December 2020

Quantitative characterization of the binding of plasminogen to intact fibrin clots, lysine-sepharose, and fibrin cleaved by plasmin

1 reference

12 December 2020

Identification of a site in fibrin(ogen) which is involved in the acceleration of plasminogen activation by tissue-type plasminogen activator

1 reference

12 December 2020

Characterization of a recombinant fusion protein of the finger domain of tissue-type plasminogen activator with a truncated single chain urokinase-type plasminogen activator

1 reference

12 December 2020

Plasminogen activation by tissue plasminogen activator in the presence of stimulating CNBr fragment FCB-2 of fibrinogen is a two-phase reaction. Kinetic analysis of the initial phase of slow plasmin formation

1 reference

12 December 2020

The FDA Advisory Panel's decision on rt-PA

1 reference

12 December 2020

The binding of plasminogen to fibrin: evidence for plasminogen-bridging

1 reference

12 December 2020

The binding of human plasminogen to fibrin and fibrinogen

1 reference

12 December 2020

A spectrophotometric solid-phase fibrin-tissue plasminogen activator activity assay (SOFIA-tPA) for high-fibrin-affinity tissue plasminogen activators

1 reference

12 December 2020

Induction of a sustained fibrinolytic response by BRL 26921 in vitro

1 reference

12 December 2020

Plasma fibronectin enhances fibrinolytic system in vitro

1 reference

12 December 2020

Resolution of dilated cardiomyopathy after surgical ablation of ventricular tachycardia in a child

1 reference

12 December 2020

Plasminogen and tissue-type plasminogen activator bind to immobilized fibronectin

1 reference

12 December 2020

Coronary thrombolysis: pharmacological considerations with emphasis on tissue-type plasminogen activator (t-PA)

1 reference

12 December 2020

Study on the mechanism of action of heparin and related substances on the fibrinolytic system: relationship between plasminogen activators and heparin

1 reference

12 December 2020

A comparative study of the efficacy and specificity of tissue plasminogen activator and pro-urokinase: demonstration of synergism and of different thresholds of non-selectivity

1 reference

12 December 2020

Binding of plasminogen to cultured human endothelial cells

1 reference

12 December 2020

Fibrin formed in plasma is composed of fibers more massive than those formed from purified fibrinogen

1 reference

12 December 2020

An enhancing effect of poly-lysine on the activation of plasminogen

1 reference

12 December 2020

Characterization of an antibody-urokinase conjugate. A plasminogen activator targeted to fibrin

1 reference

12 December 2020

Lack of interference by heparin with thrombolysis or binding of tissue-type plasminogen activator to thrombi

1 reference

12 December 2020

Thrombolysis, clot selectivity, and kinetics

1 reference

12 December 2020

Systemic thrombolytic therapy of acute myocardial infarction?

1 reference

12 December 2020

High-affinity binding sites for human Glu-plasminogen unveiled by limited plasmic degradation of human fibrin

1 reference

12 December 2020

Fibrinolytic properties of one-chain and two-chain human extrinsic (tissue-type) plasminogen activator

1 reference

12 December 2020

Common evolutionary origin of the fibrin-binding structures of fibronectin and tissue-type plasminogen activator

1 reference

12 December 2020

A critical role of lysine residues in the stimulation of tissue plasminogen activator by denatured proteins and fibrin clots

1 reference

12 December 2020

Functional properties of carbohydrate-depleted tissue plasminogen activator

1 reference

12 December 2020

Slow clearance of acylated, hybrid thrombolytic enzymes

1 reference

12 December 2020

Isolation, identification and pharmacokinetic properties of human tissue-type plasminogen activator species: possible localisation of a clearance recognition site

1 reference

12 December 2020

Fibrinolysis with acyl-enzymes: a new approach to thrombolytic therapy

1 reference

12 December 2020

Influence of cyanogen-bromide-digested fibrinogen on the kinetics of plasminogen activation by urokinase

1 reference

12 December 2020

Functional role of proteolytic cleavage at arginine-275 of human tissue plasminogen activator as assessed by site-directed mutagenesis

1 reference

12 December 2020

Fibrinogen lysine residue A alpha 157 plays a crucial role in the fibrin-induced acceleration of plasminogen activation, catalyzed by tissue-type plasminogen activator

1 reference

12 December 2020

Isolation and preliminary characterisation of active B-chain of recombinant tissue-type plasminogen activator

1 reference

12 December 2020

Initial plasmin-degradation of fibrin as the basis of a positive feed-back mechanism in fibrinolysis

1 reference

12 December 2020

Construction and expression of hybrid plasminogen activators prepared from tissue-type plasminogen activator and urokinase-type plasminogen activator genes

1 reference

12 December 2020

Binding of plasminogen to extracellular matrix

1 reference

12 December 2020

Artificial exon shuffling between tissue-type plasminogen activator (t-PA) and urokinase (u-PA): a comparative study on the fibrinolytic properties of t-PA/u-PA hybrid proteins

1 reference

12 December 2020

The effectiveness of activators in clot lysis, with special reference to fibrinolytic therapy. A new method for determination of preformed clot lysis

1 reference

12 December 2020

The level of extrinsic plasminogen activator (t-PA) during clotting as a determinant of the rate of fibrinolysis; inefficiency of activators added afterwards

1 reference

12 December 2020

Activation of immobilized plasminogen by tissue activator. Multimolecular complex formation

1 reference

12 December 2020

Kinetics of the activation of plasminogen by natural and recombinant tissue-type plasminogen activator

1 reference

12 December 2020

On the composition and function of the carbohydrate moiety of tissue-type plasminogen activator from human melanoma cells

1 reference

12 December 2020

On the interaction of the finger and the kringle-2 domain of tissue-type plasminogen activator with fibrin. Inhibition of kringle-2 binding to fibrin by epsilon-amino caproic acid

1 reference

12 December 2020

The plasmin heavy chain-urokinase conjugate: a specific thrombolytic agent

1 reference

12 December 2020

Binding of tissue-type plasminogen activator to fibrinogen fragments

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2610313

1 reference

5 September 2017

1 reference

PMC publication ID

1138828

5 September 2017

PubMed publication ID

2673218

1 reference

PMC publication ID

1138828