(Q38690434)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Teresa L Mastracci

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Crystal L Wilcox

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Casandra Panea

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Jeffrey A Golden

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Catherine Lee May

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Lori Sussel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

11 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

Developmental Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

359

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

1-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

Pancreas organogenesis: from bud to plexus to gland

11 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Influence and timing of arrival of murine neural crest on pancreatic beta cell development and maturation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Transcriptional control of acinar development and homeostasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Vagal control of pancreatic ß-cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Vertebrate endoderm development and organ formation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Identification of Arx transcriptional targets in the developing basal forebrain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Signals from the neural crest regulate beta-cell mass in the pancreas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

An illustrated review of early pancreas development in the mouse.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Opposing actions of Arx and Pax4 in endocrine pancreas development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Developmental biology of gastrin and somatostatin cells in the antropyloric mucosa of the stomach

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Notch signalling controls pancreatic cell differentiation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

NeuroD1 in the endocrine pancreas: localization and dual function as an activator and repressor.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Notochord repression of endodermal Sonic hedgehog permits pancreas development

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

The midgestational human fetal pancreas contains cells coexpressing islet hormones

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Epithelial dynamics of pancreatic branching morphogenesis

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Neural crest stem cells increase beta cell proliferation and improve islet function in co-transplanted murine pancreatic islets.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Genetic determinants of pancreatic epsilon-cell development.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Early mouse endoderm is patterned by soluble factors from adjacent germ layers.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Notochord to endoderm signaling is required for pancreas development.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3192309

Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3

31 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.08.001

Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.08.001

Development of the endocrine pancreas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.08.001

Pancreatic-duodenal homeobox 1 -role in gastric endocrine patterning

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.08.001

Ultrastructural studies of the ontogeny of fetal human and porcine endocrine pancreas, with special reference to colocalization of the four major islet hormones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.08.001

Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2011.08.001

Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21856296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21856296

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.YDBIO.2011.08.001

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21856296%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

21856296

1 reference