(Q38692105)

5 September 2017

CRISPR-Cas adaptation: insights into the mechanism of action (English)

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5 September 2017

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Gil Amitai

1

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5 September 2017

Rotem Sorek

series ordinal

2

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5 September 2017

language of work or name

English

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publication date

11 January 2016

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Nature Reviews Microbiology

5 September 2017

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5 September 2017

14

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5 September 2017

2

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5 September 2017

67-76

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https://scigraph.springernature.com/pub.10.1038/nrmicro.2015.14

5 September 2017

0 references

cites work

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Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

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Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements

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CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies.

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CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

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Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems

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Sequences spanning the leader-repeat junction mediate CRISPR adaptation to phage in Streptococcus thermophilus

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Proteins and DNA elements essential for the CRISPR adaptation process in Escherichia coli

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An updated evolutionary classification of CRISPR-Cas systems

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Small CRISPR RNAs guide antiviral defense in prokaryotes

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Structure of the CRISPR interference complex CSM reveals key similarities with cascade

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Structure of an RNA silencing complex of the CRISPR-Cas immune system.

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Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

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CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

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Detection and characterization of spacer integration intermediates in type I-E CRISPR-Cas system

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Molecular memory of prior infections activates the CRISPR/Cas adaptive bacterial immunity system

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CRISPR-spacer integration reporter plasmids reveal distinct genuine acquisition specificities among CRISPR-Cas I-E variants of Escherichia coli

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Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information

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Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

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Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity

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High-throughput analysis of type I-E CRISPR/Cas spacer acquisition in E. coli

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Pervasive generation of oppositely oriented spacers during CRISPR adaptation

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DNA motifs determining the efficiency of adaptation into the Escherichia coli CRISPR array

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Intrinsic sequence specificity of the Cas1 integrase directs new spacer acquisition

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Cas9 function and host genome sampling in Type II-A CRISPR-Cas adaptation

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Cas9 specifies functional viral targets during CRISPR-Cas adaptation.

31 March 2020

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The highly dynamic CRISPR1 system of Streptococcus agalactiae controls the diversity of its mobilome.

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The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phages

31 March 2020

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Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process

31 March 2020

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Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms.

31 March 2020

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Inter-viral conflicts that exploit host CRISPR immune systems of Sulfolobus

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Evolution and classification of the CRISPR-Cas systems

31 March 2020

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Comparative genomics of defense systems in archaea and bacteria

31 March 2020

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Foreign DNA capture during CRISPR-Cas adaptive immunity

31 March 2020

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Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems

31 March 2020

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A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair

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Crystal structure of Cas1 from Archaeoglobus fulgidus and characterization of its nucleolytic activity

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Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense

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A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats

31 March 2020

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Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein

31 March 2020

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Structure of a CRISPR-associated protein Cas2 fromDesulfovibrio vulgaris

31 March 2020

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Phage response to CRISPR-encoded resistance in Streptococcus thermophilus

31 March 2020

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Short motif sequences determine the targets of the prokaryotic CRISPR defence system

31 March 2020

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Protospacer recognition motifs: mixed identities and functional diversity

31 March 2020

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Adapting to new threats: the generation of memory by CRISPR-Cas immune systems

31 March 2020

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CRISPR adaptation biases explain preference for acquisition of foreign DNA

31 March 2020

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RecBCD enzyme and the repair of double-stranded DNA breaks

31 March 2020

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Self-targeting by CRISPR: gene regulation or autoimmunity?

31 March 2020

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Manipulating or superseding host recombination functions: a dilemma that shapes phage evolvability.

31 March 2020

1 reference

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Single-strand interruptions in replicating chromosomes cause double-strand breaks

31 March 2020

1 reference

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Rescue of arrested replication forks by homologous recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Engineered proteins detect spontaneous DNA breakage in human and bacterial cells

31 March 2020

1 reference

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The CRISPR associated protein Cas4 Is a 5' to 3' DNA exonuclease with an iron-sulfur cluster

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

The CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis contains a [2Fe-2S] cluster: crystal structure and nuclease activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Experimental definition of a clustered regularly interspaced short palindromic duplicon in Escherichia coli

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

CRISPR interference directs strand specific spacer acquisition

31 March 2020

1 reference

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Mus81-dependent double-strand DNA breaks at in vivo-generated cruciform structures in S. cerevisiae.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Crystal structure of clustered regularly interspaced short palindromic repeats (CRISPR)-associated Csn2 protein revealed Ca2+-dependent double-stranded DNA binding activity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

The basic building blocks and evolution of CRISPR-CAS systems

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Toroidal Structure and DNA Cleavage by the CRISPR-Associated [4Fe-4S] Cluster Containing Cas4 Nuclease SSO0001 from Sulfolobus solfataricus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Two distinct DNA binding modes guide dual roles of a CRISPR-Cas protein complex.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Degenerate target sites mediate rapid primed CRISPR adaptation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Casposons: a new superfamily of self-synthesizing DNA transposons at the origin of prokaryotic CRISPR-Cas immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Evolution of adaptive immunity from transposable elements combined with innate immune systems

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

CRISPR-Cas: evolution of an RNA-based adaptive immunity system in prokaryotes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

Strong bias in the bacterial CRISPR elements that confer immunity to phage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO.2015.14

The junction-resolving enzymes.

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26751509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Campylobacter jejuni acquire new host-derived CRISPR spacers when in association with bacteriophages harboring a CRISPR-like Cas4 protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26751509

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRMICRO.2015.14

1 reference

Dimensions Publication ID

5 September 2017

0 references

1 reference