(Q38693925)

5 September 2017

Immunology in the liver--from homeostasis to disease (English)

1 reference

5 September 2017

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Felix Heymann

1

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PubMed ID

26758786

5 September 2017

Frank Tacke

series ordinal

2

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PubMed ID

26758786

5 September 2017

language of work or name

English

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publication date

13 January 2016

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Nature Reviews Gastroenterology & Hepatology

5 September 2017

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5 September 2017

13

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5 September 2017

2

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5 September 2017

88-110

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https://scigraph.springernature.com/pub.10.1038/nrgastro.2015.200

5 September 2017

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The complex myeloid network of the liver with diverse functional capacity at steady state and in inflammation

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Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors.

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Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

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A lineage of myeloid cells independent of Myb and hematopoietic stem cells

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Source and characterization of hepatic macrophages in acetaminophen-induced acute liver failure in humans

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Deciphering the transcriptional network of the dendritic cell lineage

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The origin and development of nonlymphoid tissue CD103+ DCs.

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Human liver dendritic cells promote T cell hyporesponsiveness

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Liver inflammation abrogates immunological tolerance induced by Kupffer cells.

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CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens

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Human Kupffer cells secrete IL-10 in response to lipopolysaccharide (LPS) challenge

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Immune surveillance by the liver

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Combination of granulocyte colony-stimulating factor and erythropoietin improves outcomes of patients with decompensated cirrhosis

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Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

21 January 2018

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Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells.

21 January 2018

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The composition of intrahepatic lymphocytes: shaped by selective recruitment?

21 January 2018

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Frequency and phenotype of human circulating and intrahepatic natural killer cell subsets is differentially regulated according to stage of chronic liver disease

21 January 2018

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TLR-dependent cross talk between human Kupffer cells and NK cells

21 January 2018

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Re-examining the origin and function of liver-resident NK cells

21 January 2018

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A committed precursor to innate lymphoid cells

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Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells.

21 January 2018

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Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

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Chemokine receptor CXCR6-dependent hepatic NK T Cell accumulation promotes inflammation and liver fibrosis.

21 January 2018

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Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion

21 January 2018

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NKT cells from normal and tumor-bearing human livers are phenotypically and functionally distinct from murine NKT cells.

21 January 2018

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Antimicrobial activity of mucosal-associated invariant T cells

21 January 2018

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IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Systemic antigen cross-presented by liver sinusoidal endothelial cells induces liver-specific CD8 T-cell retention and tolerization.

21 January 2018

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The regulation of T-cell recruitment to the human liver during acute liver failure.

21 January 2018

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Hepatic T cells and liver tolerance

21 January 2018

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Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism.

21 January 2018

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Ito cells are liver-resident antigen-presenting cells for activating T cell responses

21 January 2018

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Human hepatic stellate cells inhibit T-cell response through B7-H1 pathway

21 January 2018

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Mechanism of T cell tolerance induction by murine hepatic Kupffer cells

21 January 2018

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Inhibition of allogeneic T-cell response by Kupffer cells expressing indoleamine 2,3-dioxygenase

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Induction of cytokine production in naive CD4(+) T cells by antigen-presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis

21 January 2018

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Hepatic stellate cells preferentially induce Foxp3+ regulatory T cells by production of retinoic acid.

21 January 2018

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PD-1/B7-H1 interaction contribute to the spontaneous acceptance of mouse liver allograft

21 January 2018

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Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Intrahepatic murine CD8 T-cell activation associates with a distinct phenotype leading to Bim-dependent death

21 January 2018

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Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatocyte entry leads to degradation of autoreactive CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Alarmins: awaiting a clinical response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

IL-33 and HMGB1 alarmins: sensors of cellular death and their involvement in liver pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Bile acid receptors as targets for drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The Cholesterol Derivative 27-Hydroxycholesterol Reduces Steatohepatitis in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Structural biology of the IL-1 superfamily: key cytokines in the regulation of immune and inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Inflammasomes: mechanism of action, role in disease, and therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The inflammasomes: guardians of the body

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Sterile inflammation in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Histones activate the NLRP3 inflammasome in Kupffer cells during sterile inflammatory liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Intravascular danger signals guide neutrophils to sites of sterile inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Extracellular ATP induces P2X7 receptor activation in mouse Kupffer cells, leading to release of IL-1β, HMGB1, and PGE2, decreased MHC class I expression and necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptors in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Alterations of the human gut microbiome in liver cirrhosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptors as targets in chronic liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

TLR-4 regulates CD8+ T cell trapping in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Cellular-specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptors and liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Tickling the TLR7 to cure viral hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

GS-9620, an oral agonist of Toll-like receptor-7, induces prolonged suppression of hepatitis B virus in chronically infected chimpanzees

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Complement alternative pathway activation in human nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Increased activity of the complement system in the liver of patients with alcoholic hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Differential contributions of C3, C5, and decay-accelerating factor to ethanol-induced fatty liver in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Complement C3 contributes to ethanol-induced liver steatosis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Complement and alcoholic liver disease: role of C1q in the pathogenesis of ethanol-induced liver injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The role of neutrophils in the development of liver diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Roles for chemokines in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Chemokines and mitochondrial products activate neutrophils to amplify organ injury during mouse acute liver failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Intravital imaging of neutrophil recruitment in hepatic ischemia-reperfusion injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Neutrophil-mediated tissue injury in alcoholic hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

IL-17A synergistically enhances bile acid-induced inflammation during obstructive cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Tissue-resident macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Exploring the full spectrum of macrophage activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Cutting Edge: Immunological Consequences and Trafficking of Human Regulatory Macrophages Administered to Renal Transplant Recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Macrophage activation and polarization: nomenclature and experimental guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Role of galectin-3 in classical and alternative macrophage activation in the liver following acetaminophen intoxication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatic allograft-derived Kupffer cells regulate T cell response in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Activation of NLRP3 and AIM2 inflammasomes in Kupffer cells in hepatic ischemia/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

VEGFR1-positive macrophages facilitate liver repair and sinusoidal reconstruction after hepatic ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Macrophages, immunity, and metabolic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The role of Kupffer cells in hepatitis B and hepatitis C virus infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Mobilizing monocytes to cross-present circulating viral antigen in chronic infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatitis C virus core protein subverts the antiviral activities of human Kupffer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Activated macrophages promote hepatitis C virus entry in a tumor necrosis factor-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

IL-1β production through the NLRP3 inflammasome by hepatic macrophages links hepatitis C virus infection with liver inflammation and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CX(3)CR1 and vascular adhesion protein-1-dependent recruitment of CD16(+) monocytes across human liver sinusoidal endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The fractalkine receptor CX₃CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Association of T-zone reticular networks and conduits with ectopic lymphoid tissues in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Lipid accumulation and dendritic cell dysfunction in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Regulation by chemokines of circulating dendritic cell precursors, and the formation of portal tract-associated lymphoid tissue, in a granulomatous liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Invariant NKT cell activation induces neutrophil accumulation and hepatitis: opposite regulation by IL-4 and IFN-γ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Protective role of interleukin-17 in murine NKT cell-driven acute experimental hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

STAT4 knockout mice are more susceptible to concanavalin A-induced T-cell hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Retinoic acid alleviates Con A-induced hepatitis and differentially regulates effector production in NKT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The CXCR3(+)CD56Bright phenotype characterizes a distinct NK cell subset with anti-fibrotic potential that shows dys-regulated activity in hepatitis C

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Natural killer p46High expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CD1 expression and CD1-restricted T cell activity in normal and tumour-bearing human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The biliary epithelium presents antigens to and activates natural killer T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

IL-22 and IL-22 binding protein (IL-22BP) regulate fibrosis and cirrhosis in hepatitis C virus and schistosome infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

NKp46-mediated killing of human and mouse hepatic stellate cells attenuates liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Natural killer cell-dependent anti-fibrotic pathway in liver injury via Toll-like receptor-9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Human mucosal associated invariant T cells detect bacterially infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

MAIT cells detect and efficiently lyse bacterially-infected epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatic interleukin-7 expression regulates T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptor 8 agonist and bacteria trigger potent activation of innate immune cells in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Intrahepatic regulatory T cells in autoimmune hepatitis are associated with treatment response and depleted with current therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

The concanavalin A model of acute hepatitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

A T cell-dependent experimental liver injury in mice inducible by concanavalin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

From immunosuppression to tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Complete differentiation of CD8+ T cells activated locally within the transplanted liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CD4 T cells promote tissue inflammation via CD40 signaling without de novo activation in a murine model of liver ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Direct, help-independent priming of CD8+ T cells by adeno-associated virus-transduced hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Ineffective CD8(+) T-cell immunity to adeno-associated virus can result in prolonged liver injury and fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Platelets mediate cytotoxic T lymphocyte-induced liver damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Immunosurveillance of the liver by intravascular effector CD8(+) T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CD40 activation rescues antiviral CD8⁺ T cells from PD-1-mediated exhaustion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Impaired CD4⁺ T cell stimulation of NK cell anti-fibrotic activity may contribute to accelerated liver fibrosis progression in HIV/HCV patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

γδT cells drive myeloid-derived suppressor cell-mediated CD8+ T cell exhaustion in hepatitis B virus-induced immunotolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Biliary obstruction results in PD-1-dependent liver T cell dysfunction and acute inflammation mediated by Th17 cells and neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Cannabinoid receptor 2 counteracts interleukin-17-induced immune and fibrogenic responses in mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Accelerated and progressive and lethal liver fibrosis in mice that lack interleukin (IL)-10, IL-12p40, and IL-13Rα2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Blockade of PD1 and TIM3 restores innate and adaptive immunity in patients with acute alcoholic hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Gut-derived lipopolysaccharide promotes T-cell-mediated hepatitis in mice through Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Liver fibrosis and repair: immune regulation of wound healing in a solid organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Mechanisms of liver fibrosis resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Scraping fibrosis: expressway to the core of fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatic fibrosis: Concept to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Role of lymphocytes in liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Inhibition of inflammatory CD4 T cell activity by murine liver sinusoidal endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatocyte growth factor favors monocyte differentiation into regulatory interleukin (IL)-10++IL-12low/neg accessory cells with dendritic-cell features

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Macrophage colony-stimulating factor drives cord blood monocyte differentiation into IL-10(high)IL-12absent dendritic cells with tolerogenic potential

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Flt3 Ligand Treatment Reverses Endotoxin Tolerance-Related Immunoparalysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Activating immunity in the liver. I. Liver dendritic cells (but not hepatocytes) are potent activators of IFN-gamma release by liver NKT cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Cross-presentation of oral antigens by liver sinusoidal endothelial cells leads to CD8 T cell tolerance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Protective role of IL-33/ST2 axis in Con A-induced hepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

IL-33--a cytokine which balances on a knife's edge?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Murine liver antigen presenting cells control suppressor activity of CD4+CD25+ regulatory T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Activation of the complement system in human nonalcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Intercellular adhesion molecule 1 (ICAM-1) expression and its role in neutrophil-induced ischemia-reperfusion injury in rat liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1β-induced chronic inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Küpffer cells promote acute rejection via induction of Th17 differentiation in rat liver allografts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Emerging roles of myeloid derived suppressor cells in hepatic inflammation and fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Cyclic adenosine monophosphate-responsive element modulator alpha overexpression impairs function of hepatic myeloid-derived suppressor cells and aggravates immune-mediated hepatitis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Natural killer T cells regulate the homing of chemokine CXC receptor 3-positive regulatory T cells to the liver in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Role of gamma-delta T cells in liver inflammation and fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Interleukin-17 exacerbates hepatic steatosis and inflammation in non-alcoholic fatty liver disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2015.200

10.1038/NRGASTRO.2015.200

31 March 2020

Identifiers

DOI

1 reference

5 September 2017

1 reference

PubMed ID

26758786