(Q38732752)

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Therapeutic Effects of FGF23 c-tail Fc in a Murine Preclinical Model of X-Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption

scientific article published on 10 June 2017

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

Therapeutic Effects of FGF23 c-tail Fc in a Murine Preclinical Model of X-Linked Hypophosphatemia Via the Selective Modulation of Phosphate Reabsorption (English)

1 reference

Europe PubMed Central

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5 September 2017

Moosa Mohammadi

20

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5 September 2017

author name string

Kristen Johnson

1

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5 September 2017

Kymberly Levine

2

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5 September 2017

Joseph Sergi

3

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5 September 2017

Jean Chamoun

4

1 reference

Europe PubMed Central

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5 September 2017

Rachel Roach

5

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5 September 2017

Jacqueline Vekich

6

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Europe PubMed Central

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5 September 2017

Mike Favis

7

1 reference

Europe PubMed Central

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5 September 2017

Mark Horn

8

1 reference

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5 September 2017

Xianjun Cao

9

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Europe PubMed Central

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5 September 2017

Brian Miller

10

1 reference

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5 September 2017

William Snyder

11

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5 September 2017

Dikran Aivazian

12

1 reference

Europe PubMed Central

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5 September 2017

William Reagan

13

1 reference

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5 September 2017

Edwin Berryman

14

1 reference

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5 September 2017

Jennifer Colangelo

15

1 reference

Europe PubMed Central

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5 September 2017

Victoria Markiewicz

16

1 reference

Europe PubMed Central

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5 September 2017

Cedo M Bagi

17

1 reference

Europe PubMed Central

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5 September 2017

Thomas P Brown

18

1 reference

Europe PubMed Central

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5 September 2017

Anthony Coyle

19

1 reference

Europe PubMed Central

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5 September 2017

Jeanne Magram

21

1 reference

Europe PubMed Central

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5 September 2017

publication date

10 June 2017

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

Journal of Bone and Mineral Research

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

Pharmacological inhibition of fibroblast growth factor (FGF) receptor signaling ameliorates FGF23-mediated hypophosphatemic rickets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Conversion of a paracrine fibroblast growth factor into an endocrine fibroblast growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Regulation of serum 1,25(OH)2 vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

A clinician's guide to X-linked hypophosphatemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Regulation of phosphate homeostasis by PTH, vitamin D, and FGF23.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Therapeutic effects of anti-FGF23 antibodies in hypophosphatemic rickets/osteomalacia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Klotho converts canonical FGF receptor into a specific receptor for FGF23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Pathogenic role of Fgf23 in Hyp mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Regulation of fibroblast growth factor-23 signaling by klotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Homozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Abnormal vitamin D metabolism in the X-linked hypophosphatemic mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Serum 1,25-dihydroxyvitamin D concentration in hypophosphatemic vitamin D-resistant rickets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5816679

31 August 2018

Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.3197

21 January 2018

Identifiers

10.1002/JBMR.3197

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 September 2017

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