(Q38741833)

English

Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance

scientific article published on 10 October 2016

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

multiple drug resistance

1 reference

based on heuristic

inferred from title

cancer-associated fibroblast

1 reference

based on heuristic

inferred from title

author name string

T Yu

1

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Europe PubMed Central

PubMed publication ID

6 September 2017

G Yang

2

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Europe PubMed Central

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6 September 2017

Y Hou

3

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Europe PubMed Central

PubMed publication ID

6 September 2017

X Tang

4

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

C Wu

5

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

X-A Wu

6

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

L Guo

7

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Q Zhu

8

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

H Luo

9

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Y-E Du

10

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

S Wen

11

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

L Xu

12

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

J Yin

13

1 reference

Europe PubMed Central

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6 September 2017

G Tu

14

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

M Liu

15

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Europe PubMed Central

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6 September 2017

language of work or name

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publication date

10 October 2016

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Europe PubMed Central

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6 September 2017

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Europe PubMed Central

PubMed publication ID

6 September 2017

36

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PubMed publication ID

6 September 2017

15

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Europe PubMed Central

PubMed publication ID

6 September 2017

2131-2145

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Europe PubMed Central

PubMed publication ID

6 September 2017

https://scigraph.springernature.com/pub.10.1038/onc.2016.370

0 references

Breast cancer in China

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Basement membranes: structure, assembly and role in tumour angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Regulation of in situ to invasive breast carcinoma transition

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Fibroblasts in cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Estrogen carcinogenesis in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

GPER mediates activation of HIF1α/VEGF signaling by estrogens

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

GPR30 regulates the EGFR-Akt cascade and predicts lower survival in patients with ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Inhibition of GPR30 by estriol prevents growth stimulation of triple-negative breast cancer cells by 17β-estradiol

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Virtual and biomolecular screening converge on a selective agonist for GPR30.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

In vivo effects of a GPR30 antagonist

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Role of GPR30 in the mechanisms of tamoxifen resistance in breast cancer MCF-7 cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs).

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

On the Origin of Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Nuclear export: DNA-binding domains find a surprising partner

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Hormone-dependent nuclear export of estradiol receptor and DNA synthesis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Shear stress causes nuclear localization of endothelial glucocorticoid receptor and expression from the GRE promoter

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Transcriptional regulation by the phosphorylation-dependent factor CREB

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

ZBTB2 increases PDK4 expression by transcriptional repression of RelA/p65

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Lactate dehydrogenase B: a metabolic marker of response to neoadjuvant chemotherapy in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Diagnostic and prognostic value of (18)F-FDG PET/CT for axillary lymph node staging in patients with breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

The reverse Warburg effect: glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Bisphenol A at low nanomolar doses confers chemoresistance in estrogen receptor-alpha-positive and -negative breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Estrogenic gper signaling regulates mir144 expression in cancer cells and cancer-associated fibroblasts (cafs)

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

G-protein-coupled receptor 30/adenylyl cyclase/protein kinase A pathway is involved in estradiol 17ß-D-glucuronide-induced cholestasis.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Tumor microenvironment-dependent 18F-FDG, 18F-fluorothymidine, and 18F-misonidazole uptake: a pilot study in mouse models of human non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Cancer-associated stroma affects FDG uptake in experimental carcinomas. Implications for FDG-PET delineation of radiotherapy target

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

The reverse Warburg effect and 18F-FDG uptake in non-small cell lung cancer A549 in mice: a pilot study

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Dependence of FDG uptake on tumor microenvironment.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Multiple blocks in the engagement of oxidative phosphorylation in putative ovarian cancer stem cells: implication for maintenance therapy with glycolysis inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Mitochondrial control by DRP1 in brain tumor initiating cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

21 January 2018

Tumor-stroma ratio in the primary tumor is a prognostic factor in early breast cancer patients, especially in triple-negative carcinoma patients

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

31 March 2020

The prognostic significance of tumor-associated stroma in invasive breast carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

31 March 2020

GPER mediates enhanced cell viability and motility via non-genomic signaling induced by 17β-estradiol in triple-negative breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

31 March 2020

Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

31 March 2020

G-protein-coupled estrogen receptor GPR30 and tamoxifen resistance in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

31 March 2020

Power surge: supporting cells "fuel" cancer cell mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FONC.2016.370

31 March 2020

G15 sensitizes epithelial breast cancer cells to doxorubicin by preventing epithelial-mesenchymal transition through inhibition of GPR30.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27721408

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrograde transport of the transmembrane estrogen receptor, G-protein-coupled-receptor-30 (GPR30/GPER) from the plasma membrane towards the nucleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27721408

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/ONC.2016.370

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 September 2017

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