(Q38749141)

6 September 2017

Defining the optimal murine models to investigate immune checkpoint blockers and their combination with other immunotherapies (English)

1 reference

6 September 2017

1 reference

1 reference

M F Sanmamed

1

1 reference

6 September 2017

C Chester

series ordinal

2

1 reference

6 September 2017

I Melero

series ordinal

3

1 reference

6 September 2017

H Kohrt

series ordinal

4

1 reference

6 September 2017

23 February 2016

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6 September 2017

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6 September 2017

27

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6 September 2017

7

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6 September 2017

1190-1198

1 reference

Trial watch: phase II and phase III attrition rates 2011-2012.

6 September 2017

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Trial watch: Phase II failures: 2008-2010.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Estimating the cost of new drug development: is it really 802 million dollars?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Analysis of cancer stem cell metastasis in xenograft animal models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Enhancement of antitumor immunity by CTLA-4 blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Inducible expression of B7-H1 (PD-L1) and its selective role in tumor site immune modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

The mighty mouse: genetically engineered mouse models in cancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Cancer modeling in the modern era: progress and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

The power of reversibility regulating gene activities via tetracycline-controlled transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Inducible in vivo genome editing with CRISPR-Cas9

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Expression of tumour-specific antigens underlies cancer immunoediting

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Applications and limitations of genetically modified mouse models in drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Of mice and men: values and liabilities of the athymic nude mouse model in anticancer drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Patient-derived xenograft models: an emerging platform for translational cancer research

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Patient-derived tumour xenografts as models for oncology drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Murine models to evaluate novel and conventional therapeutic strategies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Patient-derived xenografts, the cancer stem cell paradigm, and cancer pathobiology in the 21st century

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Human hemato-lymphoid system mice: current use and future potential for medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

A severe combined immunodeficiency mutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

RAG-1-deficient mice have no mature B and T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2Rγnull Immunodeficient Mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Anti-human CTLA-4 monoclonal antibody promotes T-cell expansion and immunity in a hu-PBL-SCID model: a new method for preclinical screening of costimulatory monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Factors affecting human T cell engraftment, trafficking, and associated xenogeneic graft-vs-host disease in NOD/SCID beta2mnull mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Development and function of human innate immune cells in a humanized mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Human CD4+ effector memory T cells persisting in the microenvironment of lung cancer xenografts are activated by local delivery of IL-12 to proliferate, produce IFN-gamma, and eradicate tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Nivolumab plus ipilimumab in advanced melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Evolving synergistic combinations of targeted immunotherapies to combat cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Combined immunostimulatory monoclonal antibodies extend survival in an aggressive transgenic hepatocellular carcinoma mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Eradication of established tumors in mice by a combination antibody-based therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Organogenesis in a dish: modeling development and disease using organoid technologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

In vivo-like growth of human tumors in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Systems Approaches towards Molecular Profiling of Human Immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

Transfer of a functional human immune system to mice with severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDW041

21 January 2018

Identifiers

DOI

10.1093/ANNONC/MDW041

1 reference

6 September 2017

1 reference