(Q38782445)

6 September 2017

title

Dihydroartemisinin restricts hepatic stellate cell contraction via an FXR-S1PR2-dependent mechanism (English)

1 reference

6 September 2017

Wenxuan Xu

1

1 reference

6 September 2017

Chunfeng Lu

2

1 reference

6 September 2017

Feng Zhang

3

1 reference

6 September 2017

Jiangjuan Shao

4

1 reference

6 September 2017

Shizhong Zheng

5

1 reference

6 September 2017

publication date

29 March 2016

1 reference

6 September 2017

1 reference

6 September 2017

volume

68

1 reference

6 September 2017

issue

5

1 reference

6 September 2017

page(s)

376-387

1 reference

Pathogenesis of liver fibrosis

6 September 2017

cites work

1 reference

Vascular biology and pathobiology of the liver: Report of a single-topic symposium

21 January 2018

1 reference

Intrahepatic angiogenesis and sinusoidal remodeling in chronic liver disease: new targets for the treatment of portal hypertension?

21 January 2018

1 reference

The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis

21 January 2018

1 reference

Hepatopoietin Cn reduces ethanol-induced hepatoxicity via sphingosine kinase 1 and sphingosine 1-phosphate receptors

21 January 2018

1 reference

Inhibition of endothelin-1-mediated contraction of hepatic stellate cells by FXR ligand

21 January 2018

1 reference

Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats

21 January 2018

1 reference

Sphingosine 1-phosphate enhances portal pressure in isolated perfused liver via S1P2 with Rho activation

21 January 2018

1 reference

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents.

21 January 2018

1 reference

A review of dihydroartemisinin as another gift from traditional Chinese medicine not only for malaria control but also for schistosomiasis control

21 January 2018

1 reference

Tetramethylpyrazine prevents ethanol-induced hepatocyte injury via activation of nuclear factor erythroid 2-related factor 2.

21 January 2018

1 reference

Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition

21 January 2018

1 reference

Curcumin attenuates ethanol-induced hepatic steatosis through modulating Nrf2/FXR signaling in hepatocytes

21 January 2018

1 reference

Tetramethylpyrazine reduces inflammation in liver fibrosis and inhibits inflammatory cytokine expression in hepatic stellate cells by modulating NLRP3 inflammasome pathway

21 January 2018

1 reference

How to prevent varices from bleeding: shades of grey--the case for nonselective beta blockers.

21 January 2018

1 reference

Molecular pathophysiology of portal hypertension.

21 January 2018

1 reference

Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo

21 January 2018

1 reference

Hepatic steatosis exacerbated by endoplasmic reticulum stress-mediated downregulation of FXR in aging mice.

21 January 2018

1 reference

Deletion of IFNγ enhances hepatocarcinogenesis in FXR knockout mice

21 January 2018

1 reference

New insights on the pathogenesis of biliary cirrhosis provided by studies in FXR knockout mice

21 January 2018

1 reference

Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease

21 January 2018

1 reference

Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expression

21 January 2018

1 reference

The FXR agonist obeticholic acid prevents gut barrier dysfunction and bacterial translocation in cholestatic rats.

21 January 2018

1 reference

Linear measurement of cell contraction in a capillary collagen gel system

21 January 2018

1 reference

Induction by latanoprost of collagen gel contraction mediated by human tenon fibroblasts: role of intracellular signaling molecules

21 January 2018

1 reference

Blebbistatin inhibits contraction and accelerates migration in mouse hepatic stellate cells

21 January 2018

1 reference

Transforming growth factor-beta induces contraction of activated hepatic stellate cells

21 January 2018

1 reference

Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2.

21 January 2018

1 reference

Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility.

21 January 2018

1 reference

Essential roles of sphingosine 1-phosphate receptor types 1 and 3 in human hepatic stellate cells motility and activation

21 January 2018

1 reference

Sphingosylphosphorylcholine induces α-smooth muscle actin expression in human lung fibroblasts and fibroblast-mediated gel contraction via S1P2 receptor and Rho/Rho-kinase pathway

21 January 2018

1 reference

Bile acids are nutrient signaling hormones

21 January 2018

1 reference

Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism

21 January 2018

1 reference

Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules

21 January 2018

1 reference

Synthetic FXR agonist GW4064 is a modulator of multiple G protein-coupled receptors

21 January 2018

1 reference

Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways.

21 January 2018

1 reference

Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle

21 January 2018

1 reference

Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin

21 January 2018

1 reference

Myosin phosphatase target subunit 1 (MYPT1) regulates the contraction and relaxation of vascular smooth muscle and maintains blood pressure

21 January 2018

1 reference

Critical illness evokes elevated circulating bile acids related to altered hepatic transporter and nuclear receptor expression

21 January 2018

1 reference

Failing FXR expression in the liver links aging to hepatic steatosis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IUB.1492

1 reference

6 September 2017

1 reference