(Q38786109)

English

Berberine activates Nrf2 nuclear translocation and inhibits apoptosis induced by high glucose in renal tubular epithelial cells through a phosphatidylinositol 3-kinase/Akt-dependent mechanism

scientific article published on 15 March 2016

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scholarly article

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Europe PubMed Central

6 September 2017

Berberine activates Nrf2 nuclear translocation and inhibits apoptosis induced by high glucose in renal tubular epithelial cells through a phosphatidylinositol 3-kinase/Akt-dependent mechanism (English)

1 reference

Europe PubMed Central

6 September 2017

author name string

Xiuli Zhang

1

1 reference

Europe PubMed Central

6 September 2017

Dan Liang

2

1 reference

Europe PubMed Central

6 September 2017

Xu Lian

3

1 reference

Europe PubMed Central

6 September 2017

Yan Jiang

4

1 reference

Europe PubMed Central

6 September 2017

Hui He

5

1 reference

Europe PubMed Central

6 September 2017

Wei Liang

6

1 reference

Europe PubMed Central

6 September 2017

Yue Zhao

7

1 reference

Europe PubMed Central

6 September 2017

Zhi-Hong Chi

8

1 reference

Europe PubMed Central

6 September 2017

publication date

15 March 2016

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Europe PubMed Central

6 September 2017

1 reference

Europe PubMed Central

6 September 2017

21

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Europe PubMed Central

6 September 2017

6

1 reference

Europe PubMed Central

6 September 2017

721-736

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Europe PubMed Central

6 September 2017

https://scigraph.springernature.com/pub.10.1007/s10495-016-1234-5

0 references

Inhibition of Src kinase blocks high glucose-induced EGFR transactivation and collagen synthesis in mesangial cells and prevents diabetic nephropathy in mice.

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Diabetes and renal tubular cell apoptosis

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Taurine prevents apoptosis induced by high ambient glucose in human tubule renal cells.

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BASP1 promotes apoptosis in diabetic nephropathy.

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Peroxiredoxin 1 inhibits the oxidative stress induced apoptosis in renal tubulointerstitial fibrosis

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Oxidative stress mediates apoptotic changes induced by hyperglycemia in human tubular kidney cells.

1 reference

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Apoptosis induced by oxalate in human renal tubular epithelial HK-2 cells

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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The tuberin/mTOR pathway promotes apoptosis of tubular epithelial cells in diabetes

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Role of reactive oxygen species in TGF-beta1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells.

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Augmenter of liver regeneration plays a protective role against hydrogen peroxide-induced oxidative stress in renal proximal tubule cells

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Molecular role of catalase on oxidative stress-induced Ca(2+) signaling and TRP cation channel activation in nervous system

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Role of oxidative stress and Ca²⁺ signaling on molecular pathways of neuropathic pain in diabetes: focus on TRP channels

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Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathway.

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An important role of Nrf2-ARE pathway in the cellular defense mechanism

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Morin mitigates acetaminophen-induced liver injury by potentiating Nrf2 regulated survival mechanism through molecular intervention in PHLPP2-Akt-Gsk3β axis.

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Mechanistic studies of the Nrf2-Keap1 signaling pathway

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The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy

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The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

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A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

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Role of the Nrf2-heme oxygenase-1 pathway in silver nanoparticle-mediated cytotoxicity

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Pharmacological and clinical aspects of heme oxygenase

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Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression

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Ameliorative effect of berberine on renal damage in rats with diabetes induced by high-fat diet and streptozotocin.

1 reference

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21 January 2018

Effects of berberine on matrix accumulation and NF-kappa B signal pathway in alloxan-induced diabetic mice with renal injury

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Renoprotective effects of berberine and its possible molecular mechanisms in combination of high-fat diet and low-dose streptozotocin-induced diabetic rats.

1 reference

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21 January 2018

Berberine protects human renal proximal tubular cells from hypoxia/reoxygenation injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways

1 reference

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Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase.

1 reference

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21 January 2018

Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth.

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21 January 2018

A method for the quantitative recovery of protein in dilute solution in the presence of detergents and lipids

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Cellular response to oxidative stress: signaling for suicide and survival

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Alpha1-adrenergic receptor stimulation induces the expression of receptor activator of nuclear factor kappaB ligand gene via protein kinase C and extracellular signal-regulated kinase pathways in MC3T3-E1 osteoblast-like cells

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Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway.

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21 January 2018

Modulation of renal tubular cell survival: where is the evidence?

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Cell apoptosis induced by zinc deficiency in osteoblastic MC3T3-E1 cells via a mitochondrial-mediated pathway

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Bax-induced cell death of Arabidopsis is meditated through reactive oxygen-dependent and -independent processes

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Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis

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Bcl-2-modifying factor induces renal proximal tubular cell apoptosis in diabetic mice

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Role of contrast media on oxidative stress, Ca(2+) signaling and apoptosis in kidney

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Berberine activates Nrf2 nuclear translocation and protects against oxidative damage via a phosphatidylinositol 3-kinase/Akt-dependent mechanism in NSC34 motor neuron-like cells

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Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy

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A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

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Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury

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21 January 2018

Identifiers

10.1007/S10495-016-1234-5

1 reference

Europe PubMed Central

6 September 2017

1 reference

Europe PubMed Central

6 September 2017

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