(Q3879131)

http://www.ebi.ac.uk/interpro/protein/Q13794

1 reference

13 November 2019

1 reference

13 November 2019

7 references

8 April 2019

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Noxa is necessary for hydrogen peroxide-induced caspase-dependent cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Noxa/Bcl-2 protein interactions contribute to bortezomib resistance in human lymphoid cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

mitochondrial outer membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

5 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13794&geneProductId=UniProtKB:Q13794

27 March 2018

BOK and NOXA are essential mediators of p53-dependent apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13794&geneProductId=UniProtKB:Q13794

27 March 2018

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13794&geneProductId=UniProtKB:Q13794

27 March 2018

The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13794&geneProductId=UniProtKB:Q13794

27 March 2018

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13794&geneProductId=UniProtKB:Q13794

1 reference

8 April 2019

Noxa in colorectal cancer: a study on DNA, mRNA and protein expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

BOK and NOXA are essential mediators of p53-dependent apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

IBA

biological process

1 reference

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

1 reference

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

cellular response to glucose starvation

1 reference

8 April 2019

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

IMP

1 reference

8 April 2019

The unfolded protein response: integrating stress signals through the stress sensor IRE1α

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of glucose metabolic process

1 reference

8 April 2019

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

reactive oxygen species metabolic process

1 reference

8 April 2019

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

cellular response to DNA damage stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

IEA

1 reference

8 April 2019

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

regulation of mitochondrial membrane permeability

1 reference

8 April 2019

The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

defense response to virus

1 reference

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of protein oligomerization

1 reference

8 April 2019

Differential contribution of Puma and Noxa in dual regulation of p53-mediated apoptotic pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of release of cytochrome c from mitochondria

5 references

8 April 2019

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Involvement of Noxa in cellular apoptotic responses to interferon, double-stranded RNA, and virus infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

proteasomal protein catabolic process

1 reference

8 April 2019

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

activation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

cellular response to hypoxia

IEA

release of cytochrome c from mitochondria

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

intrinsic apoptotic signaling pathway

IEA

1 reference

8 April 2019

The Molecular Mechanism of Noxa-induced Mitochondrial Dysfunction in p53-Mediated Cell Death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

3 references

regulation of apoptotic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

negative regulation of mitochondrial membrane potential

1 reference

8 April 2019

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of apoptotic process

ISS

3 references

8 April 2019

Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

8 April 2019

The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of DNA damage response, signal transduction by p53 class mediator

1 reference

8 April 2019

BOK and NOXA are essential mediators of p53-dependent apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

intrinsic apoptotic signaling pathway by p53 class mediator

IMP

1 reference

8 April 2019

BOK and NOXA are essential mediators of p53-dependent apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794

positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13794