(Q24312998)

2

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L Roberts

3

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T Uziel

4

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D Semizarov

5

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S W Elmore

6

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J D Leverson

7

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L T Lam

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

8

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language of work or name

English

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publication date

21 April 2011

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published in

Oncogene

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volume

30

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page(s)

1963-8

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issue

16

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cites work

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.559

20 April 2017

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.559

New molecularly targeted therapies for lung cancer

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.559

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.559

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2010.559

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

ABT-263: a potent and orally bioavailable Bcl-2 family inhibitor

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Mcl-1 is a potential therapeutic target in multiple types of cancer

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

The expression of Bcl-2 family proteins differs between nonsmall cell lung carcinoma subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Expression of apoptosis regulatory proteins of the Bcl-2 family and p53 in primary resected non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

The Bcl-2 family: roles in cell survival and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

A small molecule pan-Bcl-2 family inhibitor, GX15-070, induces apoptosis and enhances cisplatin-induced apoptosis in non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

The domains of apoptosis: a genomics perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

Myeloid cell factor-1 is a critical survival factor for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.559

21 January 2018

Identifiers

DOI

10.1038/ONC.2010.559

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1033929

1050758800

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1033929

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference