Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34312488)
Watch
English
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
title
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
main subject
mitochondrion
1 reference
based on heuristic
inferred from title
author
Maureen Murphy
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
author name string
J I-Ju Leu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Patrick Dumont
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Michael Hafey
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Donna L George
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
publication date
11 April 2004
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
published in
Nature Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
volume
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
page(s)
443-450
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/ncb1123
0 references
cites work
Mechanisms of p53-dependent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Live or let die: the cell's response to p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 has a direct apoptogenic role at the mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is p53 polymorphism maintained by natural selection?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Bcl2 family: regulators of the cellular life-or-death switch
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
VDAC2 inhibits BAK activation and mitochondrial apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transactivation-deficient mouse model provides insights into Trp53 regulation and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and subfractionation of mitochondria from animal cells and tissue culture lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NCB1123
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Dimensions Publication ID
1044505901
0 references
PubMed publication ID
15077116
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
