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Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
title
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
main subject
mitochondrion
1 reference
based on heuristic
inferred from title
author
Maureen Murphy
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
author name string
J I-Ju Leu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Patrick Dumont
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Michael Hafey
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Donna L George
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
publication date
11 April 2004
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
published in
Nature Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
volume
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
page(s)
443-450
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
cites work
Mechanisms of p53-dependent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Live or let die: the cell's response to p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 has a direct apoptogenic role at the mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is p53 polymorphism maintained by natural selection?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Bcl2 family: regulators of the cellular life-or-death switch
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
VDAC2 inhibits BAK activation and mitochondrial apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transactivation-deficient mouse model provides insights into Trp53 regulation and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation and subfractionation of mitochondria from animal cells and tissue culture lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCB1123
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NCB1123
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Dimensions Publication ID
1044505901
0 references
PubMed publication ID
15077116
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15077116
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15077116%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
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