(Q38813807)

6 September 2017

title

N-Alkyl-, 1-C-Alkyl-, and 5-C-Alkyl-1,5-dideoxy-1,5-imino-(L)-ribitols as Galactosidase Inhibitors (English)

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6 September 2017

Sophie Front

1

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6 September 2017

Estelle Gallienne

2

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6 September 2017

Julie Charollais-Thoenig

3

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6 September 2017

Stéphane Demotz

4

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6 September 2017

Olivier R Martin

5

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6 September 2017

publication date

8 December 2015

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6 September 2017

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6 September 2017

volume

11

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6 September 2017

issue

1

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6 September 2017

page(s)

133-141

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Sphingolipid lysosomal storage disorders

6 September 2017

cites work

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Enzyme replacement for lysosomal diseases

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Phenotype, diagnosis, and treatment of Gaucher's disease

21 January 2018

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The role of the iminosugar N-butyldeoxynojirimycin (miglustat) in the management of type I (non-neuronopathic) Gaucher disease: a position statement

21 January 2018

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Active-site-specific chaperone therapy for Fabry disease. Yin and Yang of enzyme inhibitors

21 January 2018

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Pharmacological chaperones as therapeutics for lysosomal storage diseases

21 January 2018

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Pharmacological Chaperone Therapy: Preclinical Development, Clinical Translation, and Prospects for the Treatment of Lysosomal Storage Disorders

21 January 2018

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Substrate reduction therapy

21 January 2018

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Pharmacological chaperone therapy for Fabry disease

21 January 2018

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A Phase 2 study of migalastat hydrochloride in females with Fabry disease: selection of population, safety and pharmacodynamic effects.

21 January 2018

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Glucosylceramide mimics: highly potent GCase inhibitors and selective pharmacological chaperones for mutations associated with types 1 and 2 Gaucher disease.

21 January 2018

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Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency.

21 January 2018

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A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.

21 January 2018

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DLHex-DGJ, a novel derivative of 1-deoxygalactonojirimycin with pharmacological chaperone activity in human G(M1)-gangliosidosis fibroblasts

21 January 2018

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Recent Insights into Inhibition, Structure, and Mechanism of Configuration-Retaining Glycosidases.

21 January 2018

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Azasugar inhibitors as pharmacological chaperones for Krabbe disease

21 January 2018

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1-Aza-sugars from D-glucose. Preparation of 1-deoxy-5-dehydroxymethyl-nojirimycin, its analogues and evaluation of glycosidase inhibitory activity

21 January 2018

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Aza-Claisen rearrangement of 2-C-hydroxymethyl glycals as a versatile strategy towards synthesis of isofagomine and related biologically important azasugars.

21 January 2018

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A new route to diverse 1-azasugars from N-Boc-5-hydroxy-3-piperidene as a common building block

21 January 2018

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Efficient and chemoselective alkylation of amines/amino acids using alcohols as alkylating reagents under mild conditions.

21 January 2018

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Synthesis of 1,5-dideoxy-1,5-iminoribitol C-glycosides through a nitrone-olefin cycloaddition domino strategy: identification of pharmacological chaperones of mutant human lysosomal β-galactosidase.

21 January 2018

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A novel human model of the neurodegenerative disease GM1 gangliosidosis using induced pluripotent stem cells demonstrates inflammasome activation

21 January 2018

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Evaluation of N-nonyl-deoxygalactonojirimycin as a pharmacological chaperone for human GM1 gangliosidosis leads to identification of a feline model suitable for testing enzyme enhancement therapy

21 January 2018

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Design and synthesis of highly potent and selective pharmacological chaperones for the treatment of Gaucher's disease

21 January 2018

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7 January 2021

Iminosugar-based galactoside mimics as inhibitors of galactocerebrosidase: SAR studies and comparison with other lysosomal galactosidases

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500485

7 January 2021

Deoxyiminoalditols from aldonolactones--V. Preparation of the four stereoisomers of 1,5-dideoxy-1,5-iminopentitols. Evaluation of these iminopentitols and three 1,5-dideoxy-1,5-iminoheptitols as glycosidase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500485

7 January 2021

Double Reductive Amination and Selective Strecker Reaction of a D-Lyxaric Aldehyde: Synthesis of Diversely Functionalized 3,4,5-Trihydroxypiperidines

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201500485

7 January 2021

Identifiers

DOI

10.1002/CMDC.201500485

1 reference

6 September 2017

1 reference