(Q38816949)

6 September 2017

title

Treatment with a Global Methyltransferase Inhibitor Induces the Intranuclear Aggregation of ALS-Linked FUS Mutant In Vitro (English)

1 reference

amyotrophic lateral sclerosis

6 September 2017

main subject

1 reference

Sakiko Fujii

1

1 reference

6 September 2017

Keisuke Takanashi

series ordinal

2

1 reference

6 September 2017

Keiko Kitajo

series ordinal

3

1 reference

6 September 2017

Atsushi Yamaguchi

series ordinal

4

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6 September 2017

publication date

24 November 2015

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6 September 2017

published in

Neurochemical Research

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6 September 2017

volume

41

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6 September 2017

issue

4

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6 September 2017

page(s)

826-835

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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

6 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Rethinking ALS: the FUS about TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

TLS and PRMT1 synergistically coactivate transcription at the survivin promoter through TLS arginine methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

The effect of PRMT1-mediated arginine methylation on the subcellular localization, stress granules, and detergent-insoluble aggregates of FUS/TLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

S-Adenosylmethionine:protein-arginine methyltransferase. Purification and mechanism of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

The physiological and pathophysiological role of PRMT1-mediated protein arginine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Protein arginine methylation in mammals: who, what, and why

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Small molecule regulators of protein arginine methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Protein arginine methyltransferase 1: positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Effects of a novel arginine methyltransferase inhibitor on T-helper cell cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Over-expression of map kinase phosphatase-1 (MKP-1) suppresses neuronal death through regulating JNK signaling in hypoxia/re-oxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

P525L FUS mutation is consistently associated with a severe form of juvenile amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

TDP-43: gumming up neurons through protein-protein and protein-RNA interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-015-1758-Z

Nuclear localization sequence of FUS and induction of stress granules by ALS mutants.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26603295

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

LIM kinase and slingshot are critical for neurite extension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26603295

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11064-015-1758-Z

1 reference

Dimensions Publication ID

6 September 2017

1011954865

0 references

1 reference