(Q38844568)

6 September 2017

title

PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma (English)

1 reference

6 September 2017

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Marialaura Petroni

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Francesca Belardinilli

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Anna Coppa

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

V Colicchia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

G Guarguaglini

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

F Sardina

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

M Sahún-Roncero

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

M Carbonari

6

1 reference

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5 June 2020

B Ricci

7

1 reference

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5 June 2020

C Heil

8

1 reference

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5 June 2020

C Capalbo

9

1 reference

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5 June 2020

I Screpanti

13

1 reference

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5 June 2020

P Lavia

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

A Gulino

15

1 reference

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5 June 2020

G Giannini

16

1 reference

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5 June 2020

language of work or name

English

0 references

publication date

10 April 2017

1 reference

6 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

36

1 reference

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5 June 2020

issue

33

1 reference

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5 June 2020

page(s)

4682-4691

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28394338%20AND%20SRC:MED&resulttype=core&format=json

The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report

5 June 2020

cites work

1 reference

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Significance of MYCN amplification in international neuroblastoma staging system stage 1 and 2 neuroblastoma: a report from the International Neuroblastoma Risk Group database

21 January 2018

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Poor survival for infants with MYCN-amplified metastatic neuroblastoma despite intensified treatment: the International Society of Paediatric Oncology European Neuroblastoma Experience

21 January 2018

1 reference

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Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification

21 January 2018

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Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

21 January 2018

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Targeted expression of MYCN causes neuroblastoma in transgenic mice

21 January 2018

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21 January 2018

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The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy

21 January 2018

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Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function

21 January 2018

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The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings

21 January 2018

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Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

21 January 2018

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An update on PARP inhibitors--moving to the adjuvant setting

21 January 2018

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

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Inhibition of poly(ADP-ribose) polymerase-1 enhances temozolomide and topotecan activity against childhood neuroblastoma.

21 January 2018

1 reference

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Inhibition of poly(ADP-Ribose) polymerase enhances the toxicity of 131I-metaiodobenzylguanidine/topotecan combination therapy to cells and xenografts that express the noradrenaline transporter

21 January 2018

1 reference

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The toxicity of nitrofuran compounds on melanoma and neuroblastoma cells is enhanced by Olaparib and ameliorated by melanin pigment

21 January 2018

1 reference

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Preclinical evaluation of the PARP inhibitor, olaparib, in combination with cytotoxic chemotherapy in pediatric solid tumors

21 January 2018

1 reference

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Emergence of micronuclei and their effects on the fate of cells under replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells

21 January 2018

1 reference

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Topoisomerase I poisoning results in PARP-mediated replication fork reversal

21 January 2018

1 reference

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Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition

21 January 2018

1 reference

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PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.

21 January 2018

1 reference

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Involvement of Myc targets in c-myc and N-myc induced human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

Rationale for poly(ADP-ribose) polymerase (PARP) inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

Non-transcriptional control of DNA replication by c-Myc

21 January 2018

1 reference

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Transient excess of MYC activity can elicit genomic instability and tumorigenesis

21 January 2018

1 reference

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c-MYC-induced genomic instability.

21 January 2018

1 reference

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Genomic instability during Myc-induced lymphomagenesis in the bursa of Fabricius

21 January 2018

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Myc induced replicative stress response: How to cope with it and exploit it.

21 January 2018

1 reference

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Cdc45 is a critical effector of myc-dependent DNA replication stress.

21 January 2018

1 reference

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Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.40

Galectin-3 impairment of MYCN-dependent apoptosis-sensitive phenotype is antagonized by nutlin-3 in neuroblastoma cells

21 January 2018

1 reference

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The HMGA1 protoncogene frequently deregulated in cancer is a transcriptional target of E2F1.

21 January 2018

1 reference

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Molecular mechanisms of MYCN-dependent apoptosis and the MDM2-p53 pathway: an Achille's heel to be exploited for the therapy of MYCN-amplified neuroblastoma

21 January 2018

1 reference

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Galectin-3 is a marker of favorable prognosis and a biologically relevant molecule in neuroblastic tumors.

21 January 2018

1 reference

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New use for an old reagent: Cell cycle analysis of DNA content using flow cytometry in formamide treated cells.

21 January 2018

1 reference

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Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells

21 January 2018

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(ADP-ribose)n participates in DNA excision repair

21 January 2018

1 reference

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MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species

21 January 2018

1 reference

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Over-expression of transfected N-myc oncogene in human SKNSH neuroblastoma cells down-regulates expression of beta 1 integrin subunit

31 March 2020

1 reference

12 December 2020

Poly (ADP-Ribose) polymerase inhibitor MK-4827 together with radiation as a novel therapy for metastatic neuroblastoma

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12 December 2020

Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells.

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12 December 2020

Inhibition of poly(ADP-ribosyl)ation in cancer: old and new paradigms revisited

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12 December 2020