(Q38885757)

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Hydroxytyrosol improves mitochondrial function and reduces oxidative stress in the brain of db/db mice: role of AMP-activated protein kinase activation.

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5 March 2020

Hydroxytyrosol improves mitochondrial function and reduces oxidative stress in the brain of db/db mice: role of AMP-activated protein kinase activation (English)

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5 March 2020

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5 March 2020

author name string

Adi Zheng

1

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5 March 2020

Hao Li

2

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5 March 2020

Jie Xu

3

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5 March 2020

Ke Cao

4

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5 March 2020

Hua Li

5

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5 March 2020

Wenjun Pu

6

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5 March 2020

Ziqi Yang

7

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5 March 2020

Yunhua Peng

8

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5 March 2020

Jiangang Long

9

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5 March 2020

Jiankang Liu

10

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5 March 2020

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17 April 2015

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5 March 2020

British Journal of Nutrition

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5 March 2020

113

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5 March 2020

11

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5 March 2020

1667-1676

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5 March 2020

Adhesion molecules, altered vasoreactivity, and brain atrophy in type 2 diabetes.

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Hyperglycemia magnifies bupivacaine-induced cell apoptosis triggered by mitochondria dysfunction and endoplasmic reticulum stress

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Hippocampal damage and memory impairments as possible early brain complications of type 2 diabetes.

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Diabetic db/db mice exhibit central nervous system and peripheral molecular alterations as seen in neurological disorders

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Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth.

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Protective role of morin, a flavonoid, against high glucose induced oxidative stress mediated apoptosis in primary rat hepatocytes

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Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model

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The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice

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Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway

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Nitric oxide and AMPK cooperatively regulate PGC-1 in skeletal muscle cells

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Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

1 reference

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Measurement of free hydroxytyrosol in microdialysates from blood and brain of anesthetized rats by liquid chromatography with fluorescence detection

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21 January 2018

Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3T3-L1 adipocytes.

1 reference

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Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways

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Major phenolic compounds in olive oil: metabolism and health effects.

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Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase II detoxifying enzyme systems in retinal pigment epithelial cells

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Hydroxytyrosol, as a component of olive mill waste water, is dose- dependently absorbed and increases the antioxidant capacity of rat plasma.

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21 January 2018

Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants

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Hydroxytyrosol reduces intracellular reactive oxygen species levels in vascular endothelial cells by upregulating catalase expression through the AMPK-FOXO3a pathway

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Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes.

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Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway

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Production of reactive oxygen species in the diabetic heart. Roles of mitochondria and NADPH oxidase

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Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

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Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

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AMPK in the brain: its roles in energy balance and neuroprotection

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SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy

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New Insights on Oxidative Stress and Diabetic Complications May Lead to a “Causal” Antioxidant Therapy

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Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation

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High glucose-induced oxidative stress and mitochondrial dysfunction in neurons.

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Effects of hydroxytyrosol-enriched sunflower oil consumption on CVD risk factors

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Nerve growth factor (NGF) and diabetic neuropathy in the rat: morphological investigations of the sural nerve, dorsal root ganglion, and spinal cord

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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Identifiers

10.1017/S0007114515000884

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25885653%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25885653%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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