(Q38888264)

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Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing.

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5 March 2020

Ovarian cancer immunotherapy using PD-L1 siRNA targeted delivery from folic acid-functionalized polyethylenimine: strategies to enhance T cell killing (English)

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5 March 2020

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5 March 2020

author name string

Pei Yun Teo

1

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5 March 2020

Chuan Yang

2

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5 March 2020

Lynsey M Whilding

3

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5 March 2020

Ana C Parente-Pereira

4

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5 March 2020

John Maher

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5 March 2020

James L Hedrick

7

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5 March 2020

Yi Yan Yang

8

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5 March 2020

Sadaf Ghaem-Maghami

9

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11 April 2015

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5 March 2020

Advanced Healthcare Materials

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5 March 2020

4

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5 March 2020

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5 March 2020

1180-1189

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5 March 2020

Rethinking ovarian cancer: recommendations for improving outcomes

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PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction

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Therapeutic PD-1 pathway blockade augments with other modalities of immunotherapy T-cell function to prevent immune decline in ovarian cancer

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Programmed death ligand-1 over-expression correlates with malignancy and contributes to immune regulation in ovarian cancer

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Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer

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Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

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Inhibitory B7-family molecules in the tumour microenvironment

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21 January 2018

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

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Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

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Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

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Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

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Effect of peptides and their introduction methods on target gene transfer of gene vector based on disulfide-containing polyethyleneimine

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FGFR-targeted gene delivery mediated by supramolecular assembly between β-cyclodextrin-crosslinked PEI and redox-sensitive PEG.

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A biodegradable amphiphilic and cationic triblock copolymer for the delivery of siRNA targeting the acid ceramidase gene for cancer therapy.

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Major degradable polycations as carriers for DNA and siRNA.

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Lipoic acid modified low molecular weight polyethylenimine mediates nontoxic and highly potent in vitro gene transfection

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Missing pieces in understanding the intracellular trafficking of polycation/DNA complexes

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Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes

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Hydrophobic modification of low molecular weight polyethylenimine for improved gene transfection.

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Mitigated cytotoxicity and tremendously enhanced gene transfection efficiency of PEI through facile one-step carbamate modification

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A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

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A step further in understanding the biology of the folate receptor in ovarian carcinoma.

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Targeting of nanoparticles: folate receptor.

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To PEGylate or not to PEGylate, that is not the question.

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Advanced materials for co-delivery of drugs and genes in cancer therapy

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Copolymer of poly(ethylene glycol) and poly(L-lysine) grafting polyethylenimine through a reducible disulfide linkage for siRNA delivery

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21 January 2018

PEG-detachable polyplex micelles based on disulfide-linked block catiomers as bioresponsive nonviral gene vectors.

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A novel approach for evaluating the efficiency of siRNAs on protein levels in cultured cells

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Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

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An acid sensitive ketal-based polyethylene glycol-oligoethylenimine copolymer mediates improved transfection efficiency at reduced toxicity

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Identifiers

10.1002/ADHM.201500089

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25866054%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25866054%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

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