(Q38889539)

7 September 2017

α-2,8-Sialyltransferase Is Involved in the Development of Multidrug Resistance via PI3K/Akt Pathway in Human Chronic Myeloid Leukemia (English)

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7 September 2017

chronic myeloid leukemia

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multiple drug resistance

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Xu Zhang

1

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7 September 2017

Weijie Dong

2

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7 September 2017

Huimin Zhou

3

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7 September 2017

Hongshuai Li

4

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7 September 2017

Ning Wang

5

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7 September 2017

Xiaoyan Miao

6

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7 September 2017

Li Jia

7

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7 September 2017

1 February 2015

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7 September 2017

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7 September 2017

67

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7 September 2017

2

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7 September 2017

77-87

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Chronic myeloid leukaemia as a model of disease evolution in human cancer

7 September 2017

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Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy

21 January 2018

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Molecular cloning and expression of a human hST8Sia VI (alpha2,8-sialyltransferase) responsible for the synthesis of the diSia motif on O-glycosylproteins

21 January 2018

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Exploring the outcome of genetic modifications of glycosylation in cultured cell lines by concurrent isolation of the major classes of vertebrate glycans

21 January 2018

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Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia.

21 January 2018

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Unique alpha 2, 8-polysialylated glycoproteins in breast cancer and leukemia cells.

21 January 2018

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Transcriptional regulation of the human Sia-alpha2,3-Gal-beta1,4-GlcNAc-R:alpha2,8-sialyltransferase (hST8Sia III) by retinoic acid in human glioblastoma tumor cell line

21 January 2018

1 reference

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

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Structure, regulation and function of PKB/AKT--a major therapeutic target

21 January 2018

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Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts

21 January 2018

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The PI3K inhibitor LY294002 blocks drug export from resistant colon carcinoma cells overexpressing MRP1.

21 January 2018

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Differential effects of selective inhibitors targeting the PI3K/AKT/mTOR pathway in acute lymphoblastic leukemia.

21 January 2018

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The human sialyltransferase family

21 January 2018

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Modification of sialylation is associated with multidrug resistance in human acute myeloid leukemia

21 January 2018

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Probing the cis interactions of the inhibitory receptor Siglec-7 with alpha2,8-disialylated ligands on natural killer cells and other leukocytes using glycan-specific antibodies and by analysis of alpha2,8-sialyltransferase gene expression

21 January 2018

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Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule.

21 January 2018

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Polysialic acid facilitates tumor invasion by glioma cells

21 January 2018

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Circadian expression and specific localization of a sialyltransferase gene in the suprachiasmatic nucleus.

21 January 2018

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Inhibition of a specific N-glycosylation activity results in attenuation of breast carcinoma cell invasiveness-related phenotypes: inhibition of epidermal growth factor-induced dephosphorylation of focal adhesion kinase

21 January 2018

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Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B-precursor acute lymphoblastic leukemia

21 January 2018

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LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance

21 January 2018

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Phosphatidylinositol-3 kinase inhibitors enhance the anti-leukemia effect of STI571.

21 January 2018

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Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.1351

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7 September 2017

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