(Q38899466)

7 September 2017

title

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice (English)

1 reference

7 September 2017

1

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6 June 2020

Catarina Leitão

2

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6 June 2020

Ioannis Gavvovidis

5

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6 June 2020

author name string

Matthias Leisegang

3

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6 June 2020

Xiaojing Chen

4

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6 June 2020

Pierre van der Bruggen

6

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6 June 2020

Wolfgang Uckert

7

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6 June 2020

Dolores J Schendel

8

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6 June 2020

Thomas Blankenstein

9

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6 June 2020

publication date

16 March 2015

1 reference

7 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25774714%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

33

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6 June 2020

issue

4

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6 June 2020

page(s)

402-407

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25774714%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nbt.3147

6 June 2020

exact match

0 references

cites work

TCRs with high affinity for foreign pMHC show self-reactivity

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12 December 2020

Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy

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Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function.

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NY-ESO-1 antigen-reactive T cell receptors exhibit diverse therapeutic capability

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Production of stable cytolytic T-cell clones directed against autologous human melanoma

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12 December 2020

Coordinated expression of clustered cancer/testis genes encoded in a large inverted repeat DNA structure

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12 December 2020

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

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12 December 2020

MAGE-1-specific precursor cytotoxic T-lymphocytes present among tumor-infiltrating lymphocytes from a patient with breast cancer: characterization and antigen-specific activation

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12 December 2020

Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette

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12 December 2020

Antigen choice in adoptive T-cell therapy of cancer

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12 December 2020

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.

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12 December 2020

Adoptive T cell therapy for cancer in the clinic

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12 December 2020

Different affinity windows for virus and cancer-specific T-cell receptors: implications for therapeutic strategies

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12 December 2020

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

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12 December 2020

Plat-E: an efficient and stable system for transient packaging of retroviruses

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12 December 2020

A MAGE-1 antigenic peptide recognized by human cytolytic T lymphocytes on HLA-A2 tumor cells

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12 December 2020

Transgenic mice with a diverse human T cell antigen receptor repertoire.

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12 December 2020

Minimal amino acid exchange in human TCR constant regions fosters improved function of TCR gene-modified T cells

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12 December 2020

Enhanced antitumor activity of T cells engineered to express T-cell receptors with a second disulfide bond.

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12 December 2020

Facilitating matched pairing and expression of TCR chains introduced into human T cells

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12 December 2020

High-throughput identification of antigen-specific TCRs by TCR gene capture

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12 December 2020

A MAGE-A1 HLA-A A*0201 epitope identified by mass spectrometry.

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12 December 2020

Redirection of antileukemic reactivity of peripheral T lymphocytes using gene transfer of minor histocompatibility antigen HA-2-specific T-cell receptor complexes expressing a conserved alpha joining region

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12 December 2020

Minimal tolerance to a tumor antigen encoded by a cancer-germline gene.

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12 December 2020

Development of human anti-murine T-cell receptor antibodies in both responding and nonresponding patients enrolled in TCR gene therapy trials

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12 December 2020

Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity

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12 December 2020

Structural and kinetic basis for heightened immunogenicity of T cell vaccines

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12 December 2020

The cancer germ-line genes MAGE-1, MAGE-3 and PRAME are commonly expressed by human myeloma cells

1 reference

12 December 2020

Peptide-specific cytotoxic T lymphocytes restricted by nonself major histocompatibility complex class I molecules: reagents for tumor immunotherapy

1 reference

12 December 2020

Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters

1 reference

12 December 2020

ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins

1 reference

12 December 2020

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity

1 reference

12 December 2020

Derivation of tumor-specific cytolytic T-cell clones from two lung cancer patients with long survival

1 reference

12 December 2020

Characterization of genetically modified T-cell receptors that recognize the CEA:691-699 peptide in the context of HLA-A2.1 on human colorectal cancer cells

1 reference

12 December 2020

Tumor eradication by wild-type p53-specific cytotoxic T lymphocytes.

1 reference

12 December 2020

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

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12 December 2020

The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100.

1 reference

12 December 2020

Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection

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12 December 2020

Tolerance to p53 by A2.1-restricted cytotoxic T lymphocytes.

1 reference

12 December 2020

A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.

1 reference

12 December 2020

Efficient gene transfer into primary human CD8+ T lymphocytes by MuLV-10A1 retrovirus pseudotype

1 reference

12 December 2020

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

1 reference

12 December 2020

Cytolytic T lymphocytes recognize an antigen encoded by MAGE-A10 on a human melanoma

1 reference

12 December 2020

A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire

1 reference

12 December 2020

It's the peptide-MHC affinity, stupid.

1 reference

12 December 2020

Retroviral vectors for high-level transgene expression in T lymphocytes

1 reference

12 December 2020

Identifiers

DOI

10.1038/NBT.3147

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25774714%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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