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Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
title
Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
main subject
stem-cell quiescence
1 reference
based on heuristic
inferred from title
author
Francesca Ficara
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author name string
Mark J Murphy
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
Min Lin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
Michael L Cleary
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
language of work or name
English
0 references
publication date
1 May 2008
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
published in
Cell Stem Cell
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
page(s)
484-496
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
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B-cell development fails in the absence of the Pbx1 proto-oncogene
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Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells
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The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
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Cell intrinsic alterations underlie hematopoietic stem cell aging.
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A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny
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Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells
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Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs
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Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.
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Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1
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Pbx1 is essential for adrenal development and urogenital differentiation
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Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney
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Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus
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Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation
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The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver
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Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
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14 September 2017
Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
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Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential
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Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.
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22 August 2018
Smad7 promotes self-renewal of hematopoietic stem cells
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22 August 2018
p57Kip2 is expressed in quiescent mouse bone marrow side population cells.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2416441
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22 August 2018
p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2416441
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22 August 2018
Zfx: at the crossroads of survival and self-renewal
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/18462698
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based on heuristic
inferred from PubMed ID database lookup
Hematopoietic stem cell quiescence maintained by p21cip1/waf1
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18462698
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/18462698
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.STEM.2008.03.004
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PMCID
2416441
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PubMed ID
18462698
1 reference
stated in
Europe PubMed Central
PMCID
2416441
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18462698%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
ResearchGate publication ID
5388300
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