(Q38921106)

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Curcumin inhibits proliferation-migration of NSCLC by steering crosstalk between a Wnt signaling pathway and an adherens junction via EGR-1.

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Europe PubMed Central

PubMed publication ID

7 September 2017

Curcumin inhibits proliferation-migration of NSCLC by steering crosstalk between a Wnt signaling pathway and an adherens junction via EGR-1. (English)

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Europe PubMed Central

PubMed publication ID

7 September 2017

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non-small-cell lung carcinoma

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based on heuristic

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author name string

Qing-yong Chen

1

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Europe PubMed Central

PubMed publication ID

7 September 2017

De-min Jiao

2

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Europe PubMed Central

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7 September 2017

Li-feng Wang

3

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Europe PubMed Central

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7 September 2017

Lishan Wang

4

1 reference

Europe PubMed Central

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7 September 2017

Hui-zhen Hu

5

1 reference

Europe PubMed Central

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7 September 2017

Jia Song

6

1 reference

Europe PubMed Central

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7 September 2017

Jie Yan

7

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Li-jun Wu

8

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Europe PubMed Central

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7 September 2017

Jian-guo Shi

9

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7 September 2017

publication date

12 January 2015

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Europe PubMed Central

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7 September 2017

Molecular BioSystems

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Europe PubMed Central

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7 September 2017

11

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Europe PubMed Central

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7 September 2017

3

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Europe PubMed Central

PubMed publication ID

7 September 2017

859-868

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Europe PubMed Central

PubMed publication ID

7 September 2017

Cancer statistics, 2013

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The curcumin analog EF24 targets NF-κB and miRNA-21, and has potent anticancer activity in vitro and in vivo

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Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs

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Difluorinated-curcumin (CDF) restores PTEN expression in colon cancer cells by down-regulating miR-21

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Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway

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Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells

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Curcumin induces apoptosis and inhibits growth of orthotopic human non-small cell lung cancer xenografts.

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Curcumin suppresses proliferation and invasion in non-small cell lung cancer by modulation of MTA1-mediated Wnt/β-catenin pathway

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Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF).

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From molecular to modular cell biology

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Cross-talk between signaling pathways can generate robust oscillations in calcium and cAMP.

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Scalable rule-based modelling of allosteric proteins and biochemical networks

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Cross-talk between MET and EGFR in non-small cell lung cancer involves miR-27a and Sprouty2.

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Interaction between the bone morphogenetic proteins and Ras/MAP-kinase signalling pathways in lung cancer.

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Dynamic network of transcription and pathway crosstalk to reveal molecular mechanism of MGd-treated human lung cancer cells

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Collateral missing value imputation: a new robust missing value estimation algorithm for microarray data

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

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Variance stabilization applied to microarray data calibration and to the quantification of differential expression

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RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis

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The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

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Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains

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Human protein reference database--2006 update

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TRANSFAC: transcriptional regulation, from patterns to profiles

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Curcumin and cancer cells: how many ways can curry kill tumor cells selectively?

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The cadherin-catenin adhesion system in signaling and cancer

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Metastatic cancer cell

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21 January 2018

Sticky business: orchestrating cellular signals at adherens junctions

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21 January 2018

Curcumin attenuates β-catenin signaling in prostate cancer cells through activation of protein kinase D1.

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Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis.

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21 January 2018

Curcumin suppresses migration and proliferation of Hep3B hepatocarcinoma cells through inhibition of the Wnt signaling pathway

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21 January 2018

Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling.

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21 January 2018

Wnt signaling pathway in non-small cell lung cancer

1 reference

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21 January 2018

Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines

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21 January 2018

Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells

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Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma

1 reference

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Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools

1 reference

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The Wnt pathway destabilizes adherens junctions and promotes cell migration via β-catenin and its target gene cyclin D1.

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21 January 2018

Functional and pathway enrichment analysis for integrated regulatory network of high- and low-metastatic lung cancer

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Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha

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Extracellular matrix determinants and the regulation of cancer cell invasion stratagems

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T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells

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Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

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Identifiers

10.1039/C4MB00336E

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

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