(Q38923448)

7 September 2017

title

PINK1 phosphorylates transglutaminase 2 and blocks its proteasomal degradation (English)

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7 September 2017

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Boram Min

1

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7 September 2017

Young-Chang Kwon

series ordinal

2

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7 September 2017

Kwang-Min Choe

series ordinal

3

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7 September 2017

Kwang Chul Chung

series ordinal

4

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7 September 2017

publication date

29 December 2014

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Journal of Neuroscience Research

7 September 2017

published in

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7 September 2017

volume

93

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7 September 2017

issue

5

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7 September 2017

page(s)

722-735

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Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity

7 September 2017

cites work

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Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

21 January 2018

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Parkinson's disease: a genetic perspective

21 January 2018

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PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR.

21 January 2018

1 reference

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

1 reference

Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications

21 January 2018

1 reference

Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

21 January 2018

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Overexpression of transglutaminase in the Drosophila wing imaginal disc induced an extra wing crossvein phenotype.

21 January 2018

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Degradation of transglutaminase 2 by calcium-mediated ubiquitination responding to high oxidative stress

21 January 2018

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Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies

21 January 2018

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Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

21 January 2018

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Genetics of Parkinson's disease

21 January 2018

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

21 January 2018

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Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation

21 January 2018

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

21 January 2018

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Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

21 January 2018

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Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.

21 January 2018

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Etiology and pathogenesis of Parkinson's disease

21 January 2018

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 January 2018

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PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

21 January 2018

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Protein crosslinking by transglutaminase controls cuticle morphogenesis in Drosophila

21 January 2018

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Cell type-specific activation of intracellular transglutaminase 2 by oxidative stress or ultraviolet irradiation: implications of transglutaminase 2 in age-related cataractogenesis

21 January 2018

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Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.

21 January 2018

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Molecular interaction between parkin and PINK1 in mammalian neuronal cells

21 January 2018

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Formation of parkin aggregates and enhanced PINK1 accumulation during the pathogenesis of Parkinson's disease

21 January 2018

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Over-expression of transglutaminase in the Drosophila eye imaginal disc induces a rough eye phenotype

21 January 2018

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

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Tissue transglutaminase cross-links beclin 1 and regulates autophagy in MPP⁺-treated human SH-SY5Y cells

21 January 2018

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

21 January 2018

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Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila

21 January 2018

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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

21 January 2018

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Phosphorylation of transglutaminase 2 (TG2) at serine-216 has a role in TG2 mediated activation of nuclear factor-kappa B and in the downregulation of PTEN

21 January 2018

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Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

21 January 2018

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Transglutaminase 2 promotes both caspase-dependent and caspase-independent apoptotic cell death via the calpain/Bax protein signaling pathway

21 January 2018

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The kinase domain of mitochondrial PINK1 faces the cytoplasm

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.23535

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7 September 2017

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