(Q38943647)

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ATF2 contributes to cisplatin resistance in non-small cell lung cancer and celastrol induces cisplatin resensitization through inhibition of JNK/ATF2 pathway.

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22 February 2020

ATF2 contributes to cisplatin resistance in non-small cell lung cancer and celastrol induces cisplatin resensitization through inhibition of JNK/ATF2 pathway (English)

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22 February 2020

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Marco Lo Iacono

1

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22 February 2020

Valentina Monica

2

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22 February 2020

Silvia Saviozzi

5

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22 February 2020

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Tiziana Vavalà

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22 February 2020

Mara Gisabella

4

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22 February 2020

Enrico Bracco

6

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22 February 2020

Silvia Novello

7

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22 February 2020

Mauro Papotti

8

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22 February 2020

Giorgio Vittorio Scagliotti

9

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22 February 2020

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12 November 2014

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22 February 2020

International Journal of Cancer

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22 February 2020

136

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22 February 2020

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22 February 2020

2598-2609

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22 February 2020

Cancer statistics, 2009

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

A randomized phase II study of pemetrexed in combination with cisplatin or carboplatin as first-line therapy for patients with locally advanced or metastatic non-small-cell lung cancer.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Transcription factor ATF2 regulation by the JNK signal transduction pathway

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

The role of ATF-2 in oncogenesis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol suppresses allergen-induced airway inflammation in a mouse allergic asthma model

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Apoptosis Induction in HL-60 Cells and Inhibition of Topoisomerase II by Triterpene Celastrol

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Preclinical studies of celastrol and acetyl isogambogic acid in melanoma.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol causes apoptosis and cell cycle arrest in rat glioma cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol, a novel HSP90 inhibitor, depletes Bcr-Abl and induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol induces apoptosis in non-small-cell lung cancer A549 cells through activation of mitochondria- and Fas/FasL-mediated pathways

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol potentiates radiotherapy by impairment of DNA damage processing in human prostate cancer

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Celastrol inhibits production of nitric oxide and proinflammatory cytokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Effects of demethylzeylasteral and celastrol on spermatogenic cell Ca2+ channels and progesterone-induced sperm acrosome reaction

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Chronic inhibition of cardiac Kir2.1 and HERG potassium channels by celastrol with dual effects on both ion conductivity and protein trafficking.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Opposing roles for ATF2 and c-Fos in c-Jun-mediated neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

ATF2 confers radiation resistance to human melanoma cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

A role for ATF2 in regulating MITF and melanoma development

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

The c-jun kinase/stress-activated pathway: regulation, function and role in human disease

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Inhibition of melanoma growth and metastasis by ATF2-derived peptides.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Growth factor stimulation induces cell survival by c-Jun. ATF2-dependent activation of Bcl-XL.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Non-small cell lung cancer exhibits transcript overexpression of genes associated with homologous recombination and DNA replication pathways

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Polymerase eta mRNA expression predicts survival of non-small cell lung cancer patients treated with platinum-based chemotherapy.

1 reference

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21 January 2018

Aurora Kinase A expression is associated with lung cancer histological-subtypes and with tumor de-differentiation.

1 reference

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21 January 2018

Effect of cigarette smoke extract on dendritic cells and their impact on T-cell proliferation.

1 reference

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21 January 2018

DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29302

21 January 2018

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

1 reference

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21 January 2018

Identifiers

10.1002/IJC.29302

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359574%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25359574%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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