(Q38961897)

8 September 2017

title

Molecular characterization of immortalized normal and dysplastic oral cell lines (English)

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8 September 2017

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Christopher T D Dickman

1

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8 September 2017

Rebecca Towle

2

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8 September 2017

Rajan Saini

3

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8 September 2017

Cathie Garnis

4

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8 September 2017

publication date

28 August 2014

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Journal of Oral Pathology & Medicine

8 September 2017

published in

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8 September 2017

volume

44

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8 September 2017

issue

5

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8 September 2017

page(s)

329-336

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describes a project that uses

8 September 2017

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Human beta-defensins: differential activity against candidal species and regulation by Candida albicans

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Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer

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Correlation of dyskerin expression with active proliferation independent of telomerase

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Multi-functional nanocarriers to overcome tumor drug resistance

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Integrative molecular characterization of head and neck cancer cell model genomes

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

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Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer

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High-resolution copy number and gene expression microarray analyses of head and neck squamous cell carcinoma cell lines of tongue and larynx

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Establishment of OC3 oral carcinoma cell line and identification of NF-kappa B activation responses to areca nut extract

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The serial cultivation of human diploid cell strains

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Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.

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Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination

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Extension of life-span by introduction of telomerase into normal human cells

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An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor

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Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs).

21 January 2018

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A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status

21 January 2018

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Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

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The p53 status of cultured human premalignant oral keratinocytes

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Global analysis of DNA methylation changes during progression of oral cancer

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DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers.

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Multiple aberrations of chromosome 3p detected in oral premalignant lesions

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A stepwise framework for the normalization of array CGH data

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MD-SeeGH: a platform for integrative analysis of multi-dimensional genomic data

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waviCGH: a web application for the analysis and visualization of genomic copy number alterations

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KEGG: kyoto encyclopedia of genes and genomes

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Cytoscape 2.8: new features for data integration and network visualization

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ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

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A novel and universal method for microRNA RT-qPCR data normalization

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Characterization of transformation related genes in oral cancer cells

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers

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Surveillance mechanism linking Bub1 loss to the p53 pathway

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Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

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Negative regulation of the tumor suppressor p53 gene by microRNAs.

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A survey of telomerase activity in human cancer

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Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome.

21 January 2018

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Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss.

21 January 2018

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Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

21 January 2018

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Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells

21 January 2018

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Regulation of terminal differentiation of cultured human keratinocytes by vitamin A.

21 January 2018

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Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization

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Alteration of cell-cycle regulatory proteins in human oral epithelial cells immortalized by HPV16 E6 and E7.

21 January 2018

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Global gene expression profiling of oral cavity cancers suggests molecular heterogeneity within anatomic subsites

21 January 2018

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Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins.

21 January 2018

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Global epidemiology of oral and oropharyngeal cancer

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JOP.12236

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8 September 2017

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