(Q38968564)

8 September 2017

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title

Epigenetic Variability of CD4+CD25+ Tregs Contributes to the Pathogenesis of Autoimmune Diseases (English)

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8 September 2017

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Ye Shu

1

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8 September 2017

Qinghua Hu

2

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8 September 2017

Hai Long

3

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8 September 2017

Christopher Chang

4

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8 September 2017

Qianjin Lu

5

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8 September 2017

Rong Xiao

6

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8 September 2017

29 September 2016

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Clinical Reviews in Allergy & Immunology

8 September 2017

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8 September 2017

52

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8 September 2017

2

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8 September 2017

260-272

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https://scigraph.springernature.com/pub.10.1007/s12016-016-8590-3

8 September 2017

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cites work

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 January 2018

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

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Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

21 January 2018

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An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development.

21 January 2018

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Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells

21 January 2018

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A two-step process for thymic regulatory T cell development.

21 January 2018

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FoxP3 inhibits proliferation and induces apoptosis of gastric cancer cells by activating the apoptotic signaling pathway

21 January 2018

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To be or not to be a Treg cell: lineage decisions controlled by epigenetic mechanisms

21 January 2018

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Epigenetic control of the foxp3 locus in regulatory T cells

21 January 2018

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DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

21 January 2018

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CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation.

21 January 2018

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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

21 January 2018

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Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation

21 January 2018

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Aging is associated with increased regulatory T-cell function

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Peripheral whole blood FOXP3 TSDR methylation: a potential marker in severity assessment of autoimmune diseases and chronic infections.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Epigenetic biomarkers of T-cells in human glioma.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3).

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Regulatory T cell DNA methyltransferase inhibition accelerates resolution of lung inflammation

21 January 2018

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Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions

21 January 2018

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The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

21 January 2018

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Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Differential coupling of KLF10 to Sin3-HDAC and PCAF regulates the inducibility of the FOXP3 gene

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Deacetylase inhibition promotes the generation and function of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Boosting regulatory T cells limits neuroinflammation in permanent cortical stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Critical role of histone demethylase Jmjd3 in the regulation of CD4+ T-cell differentiation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Cutting edge: the Foxp3 target miR-155 contributes to the development of regulatory T cells.

21 January 2018

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Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

MicroRNA-126 regulates the induction and function of CD4(+) Foxp3(+) regulatory T cells through PI3K/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

MicroRNA 10a marks regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Class I and II histone deacetylase inhibition by ITF2357 reduces SLE pathogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

The influence of therapy on CD4+CD25(high)FOXP3+ regulatory T cells in systemic lupus erythematosus patients: a prospective study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

A77 1726, the active metabolite of leflunomide, attenuates lupus nephritis by promoting the development of regulatory T cells and inhibiting IL-17-producing double negative T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3⁺ regulatory T cells in MRL/lpr mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Activated and resting regulatory T cell exhaustion concurs with high levels of interleukin-22 expression in systemic sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Peripheral blood regulatory T cells in patients with diffuse systemic sclerosis (SSc) before and after autologous hematopoietic SCT: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

DNA hypermethylation of the forkhead box protein 3 (FOXP3) promoter in CD4+ T cells of patients with systemic sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

CD4+CD25(high)CD127(low/-) Treg cell frequency from peripheral blood correlates with disease activity in patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

A novel upstream enhancer of FOXP3, sensitive to methylation-induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Methotrexate Restores Regulatory T Cell Function Through Demethylation of the FoxP3 Upstream Enhancer in Patients With Rheumatoid Arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Kaempferol enhances the suppressive function of Treg cells by inhibiting FOXP3 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Dual-specificity phosphatase 5 attenuates autoimmune arthritis in mice via reciprocal regulation of the Th17/Treg cell balance and inhibition of osteoclastogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Rebamipide suppresses collagen-induced arthritis through reciprocal regulation of th17/treg cell differentiation and heme oxygenase 1 induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Rebamipide attenuates autoimmune arthritis severity in SKG mice via regulation of B cell and antibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Poly(ADP-ribose) polymerase-1 inhibitor modulates T regulatory and IL-17 cells in the prevention of adjuvant induced arthritis in mice model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Up-regulation of microRNA-210 induces immune dysfunction via targeting FOXP3 in CD4(+) T cells of psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Th1, Th2, Th17 and regulatory T cell pattern in psoriatic patients: modulation of cytokines and gene targets induced by etanercept treatment and correlation with clinical response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Photo(chemo)therapy reduces circulating Th17 cells and restores circulating regulatory T cells in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involving CTLA4 signaling in a psoriasis-like skin disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

DNA methylation impairs TLR9 induced Foxp3 expression by attenuating IRF-7 binding activity in fulminant type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Altered microRNA Expression and Immunosuppressive Cytokine Production by Regulatory T Cells of Ulcerative Colitis Patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Altered miRNA expression in T regulatory cells in course of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

miR26a modulates Th17/T reg balance in the EAE model of multiple sclerosis by targeting IL6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

microRNA-17-92 regulates IL-10 production by regulatory T cells and control of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Beta2-adrenergic receptor signaling in CD4+ Foxp3+ regulatory T cells enhances their suppressive function in a PKA-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12016-016-8590-3

Regulatory T cells in the skin lesions and blood of patients with systemic sclerosis and morphoea

21 January 2018

1 reference

12 December 2020

CD4+CD25highFOXP3+ T regulatory cells as a biomarker of disease activity in systemic lupus erythematosus: a prospective study

1 reference

12 December 2020

CD4+ CD25+ T-regulatory cells in psoriasis. Correlation between their numbers and biologics-induced clinical improvement

1 reference

12 December 2020

The imbalance between regulatory and IL-17-secreting CD4+ T cells in lupus patients

1 reference

12 December 2020

Endogenous FOXP3 inhibits cell proliferation, migration and invasion in glioma cells

1 reference

12 December 2020

Increase of peripheral T regulatory cells during remission induction with cyclophosphamide in active systemic lupus erythematosus

1 reference

12 December 2020

Hypomethylating Agent 5-Aza-2′-deoxycytidine (DAC) Ameliorates Multiple Sclerosis in Mouse Models

1 reference

12 December 2020

A novel role for KLF14 in T regulatory cell differentiation

1 reference

12 December 2020

Rapamycin regulates iTreg function through CD39 and Runx1 pathways

1 reference

12 December 2020

Epigenetic modifications and improved regulatory T-cell function in subjects undergoing dual sublingual immunotherapy

1 reference

12 December 2020

Flow cytometric analyses of circulating regulatory T cells in patients with dermatitis herpetiformis and other immune mediated dermatoses

1 reference

12 December 2020

Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis

1 reference

12 December 2020

Decreased expression of Runx1 and lowered proportion of Foxp3⁺ CD25⁺ CD4⁺ regulatory T cells in systemic sclerosis

1 reference

12 December 2020

Total glucosides of paeony induces regulatory CD4(+)CD25(+) T cells by increasing Foxp3 demethylation in lupus CD4(+) T cells

1 reference

12 December 2020

Forkhead box protein 3 (FOXP3) hypermethylation is associated with diesel exhaust exposure and risk for childhood asthma

1 reference

12 December 2020

Reduction of regulatory T cells in skin lesions but not in peripheral blood of patients with systemic scleroderma

1 reference

12 December 2020

Study of T helper (17) and T regulatory cells in psoriatic patients receiving live attenuated varicella vaccine therapy in a randomized controlled trial

1 reference

12 December 2020

Relatively increased number of liver Foxp(3+) regulatory T cells against hepatic lesions in murine lupus

1 reference

12 December 2020

Disturbed Th17/Treg balance in patients with rheumatoid arthritis

1 reference

12 December 2020

Ambient air pollution impairs regulatory T-cell function in asthma

1 reference

12 December 2020

(99) Tc-methylene diphosphonate improves rheumatoid arthritis disease activity by increasing the frequency of peripheral γδ T cells and CD4(+) CD25(+) Foxp3(+) Tregs

1 reference

12 December 2020

[Study of fas-mediated Foxp3+CD4+CD25+ Treg cell apoptosis in patients with systemic lupus erythematosus]

1 reference

12 December 2020

[Expression and significance of Th17 and Treg cells in peripheral blood of patients with systemic lupus erythematosus]

1 reference

12 December 2020

microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients

1 reference

12 December 2020

Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin

1 reference

12 December 2020

10.1007/S12016-016-8590-3

Identifiers

DOI

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Dimensions Publication ID

8 September 2017

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1 reference