(Q38969133)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25088204%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

title

Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation (English)

1 reference

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11 March 2020

0 references

1 reference

1 reference

2

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11 March 2020

author name string

L Yan

1

1 reference

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11 March 2020

Y Gao

3

1 reference

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11 March 2020

S Ghazal

4

1 reference

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11 March 2020

L Lu

5

1 reference

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11 March 2020

S Bellone

6

1 reference

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11 March 2020

Y Yang

7

1 reference

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11 March 2020

N Liu

8

1 reference

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11 March 2020

X Zhao

9

1 reference

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11 March 2020

A D Santin

10

1 reference

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11 March 2020

H Taylor

11

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11 March 2020

Y Huang

12

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11 March 2020

language of work or name

English

0 references

publication date

4 August 2014

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11 March 2020

1 reference

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11 March 2020

volume

34

1 reference

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11 March 2020

issue

23

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11 March 2020

page(s)

3076-3084

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https://scigraph.springernature.com/pub.10.1038/onc.2014.236

11 March 2020

exact match

0 references

cites work

The H19 locus: role of an imprinted non-coding RNA in growth and development.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The increasing complexity of the oncofetal h19 gene locus: functional dissection and therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Expression of the imprinted H19 oncofetal RNA in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

H19 and IGF2 gene expression in human normal, hyperplastic, and malignant endometrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The H19 non-coding RNA is essential for human tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The H19 locus acts in vivo as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Breast cancer genome-wide association studies: there is strength in numbers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The imprinted H19 lncRNA antagonizes let-7 microRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The let-7 family of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Role of microRNA let-7 and effect to HMGA2 in esophageal squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Pivotal role of reduced let-7g expression in breast cancer invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

miR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The Lin28/let-7 axis regulates glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The let-7-Imp axis regulates ageing of the Drosophila testis stem-cell niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

HMGA2 is a driver of tumor metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

How does Lin28 let-7 control development and disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

RNA-binding protein insulin-like growth factor II mRNA-binding protein 3 expression promotes tumor invasion and predicts early recurrence and poor prognosis in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

IMP3 is a novel biomarker for triple negative invasive mammary carcinoma associated with a more aggressive phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Regulation of IMP3 by EGFR signaling and repression by ERβ: implications for triple-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

RNA-binding IMPs promote cell adhesion and invadopodia formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

let-7 regulates Dicer expression and constitutes a negative feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Biomarkers for epithelial-mesenchymal transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Potential applications for biguanides in oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin and cancer stem cells: old drug, new targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin inhibits cell proliferation, migration and invasion by attenuating CSC function mediated by deregulating miRNAs in pancreatic cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Low concentrations of metformin selectively inhibit CD133⁺ cell proliferation in pancreatic cancer and have anticancer action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Let-7a regulation of insulin-like growth factors in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Meta-analysis of transcriptome reveals let-7b as an unfavorable prognostic biomarker and predicts molecular and clinical subclasses in high-grade serous ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Transient cyclical methylation of promoter DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

The dynamics of DNA methylation in schizophrenia and related psychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin targets c-MYC oncogene to prevent prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Constitutive proteasomal degradation of TWIST-1 in epithelial-ovarian cancer stem cells impacts differentiation and metastatic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Lin28 regulates HER2 and promotes malignancy through multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Tumour-suppressor activity of H19 RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Metformin inhibits the development and metastasis of ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.236

Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues

31 March 2020

1 reference

12 December 2020

Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cells

1 reference

12 December 2020

Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes

1 reference

12 December 2020

H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19.

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.236

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25088204%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 March 2020

1053261788

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25088204%20AND%20SRC:MED&resulttype=core&format=json