(Q38972333)

8 September 2017

title

Pre-clinical analysis of changes in intra-cellular biochemistry of glioblastoma multiforme (GBM) cells due to c-Myc silencing (English)

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8 September 2017

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Vishal Rajagopalan

1

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8 September 2017

Muthukumar Vaidyanathan

series ordinal

2

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8 September 2017

Vanisree Arambakkam Janardhanam

series ordinal

3

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8 September 2017

James E Bradner

series ordinal

4

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8 September 2017

publication date

24 July 2014

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Cellular and Molecular Neurobiology

8 September 2017

published in

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8 September 2017

volume

34

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8 September 2017

issue

7

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8 September 2017

page(s)

1059-1069

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https://scigraph.springernature.com/pub.10.1007/s10571-014-0083-4

8 September 2017

exact match

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cites work

Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications.

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Inhibition of BET bromodomain targets genetically diverse glioblastoma

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The Bcl-2 family: roles in cell survival and oncogenesis.

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c-Myc target genes involved in cell growth, apoptosis, and metabolism

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Links between metabolism and cancer

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Temozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells.

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BET bromodomain inhibition as a therapeutic strategy to target c-Myc

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Effect of Naringenin on metabolic markers, lipid profile and expression of GFAP in C6 glioma cells implanted rat's brain

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Akt and c-Myc differentially activate cellular metabolic programs and prime cells to bioenergetic inhibition

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Cooperative interaction between c-myc and bcl-2 proto-oncogenes

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Glucose utilization via glycogen phosphorylase sustains proliferation and prevents premature senescence in cancer cells

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Selective inhibition of BET bromodomains

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Mitochondrial structure, function and dynamics are temporally controlled by c-Myc

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Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment.

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MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Pr

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iNOS: a potential therapeutic target for malignant glioma

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Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo

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c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry

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Myc-dependent Mitochondrial Generation of Acetyl-CoA Contributes to Fatty Acid Biosynthesis and Histone Acetylation during Cell Cycle Entry

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Genetic alterations and signaling pathways in the evolution of gliomas

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Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

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Autophagy in the cellular energetic balance

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Identification of human brain tumour initiating cells

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Metabolic modulation of epigenetics in gliomas

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Bromodomain and extraterminal (BET) protein inhibition suppresses human T cell leukemia virus 1 (HTLV-1) Tax protein-mediated tumorigenesis by inhibiting nuclear factor κB (NF-κB) signaling

21 January 2018

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Global mapping of c-Myc binding sites and target gene networks in human B cells

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Dysregulated lipid metabolism in cancer

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Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

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MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

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Transcription factors as targets for cancer therapy

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12 December 2020

Insights from Bcl-2 and Myc: malignancy involves abrogation of apoptosis as well as sustained proliferation.

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12 December 2020

Down-regulation of c-myc and bcl-2 gene expression in PU.1-induced apoptosis in murine erythroleukemia cells

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12 December 2020

A matter of life and cell death

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12 December 2020

BET bromodomain proteins mediate downstream signaling events following growth factor stimulation in human lung fibroblasts and are involved in bleomycin-induced pulmonary fibrosis

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12 December 2020

BET bromodomain inhibition of MYC-amplified medulloblastoma.

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12 December 2020

The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis.

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12 December 2020

10.1007/S10571-014-0083-4

Identifiers

DOI

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Dimensions Publication ID

8 September 2017

1026815916

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1 reference